Title: Book The Best Hotels in O Brien, FL for 2025 from CA $82 - Competitive Prices - Expedia.ca [Vacation Rentals in O Brien](https://expedia.ca/O-Brien-Vacation-Rentals.d3000431472.Travel-Guide-VacationRentals)[O Brien Car Rentals](https://expedia.ca/Car-Rentals-In-O-Brien.d3000431472.Car-Rental-Guide)[O Brien Vacation Packages](https://expedia.ca/O-Brien.d3000431472.Destination-Travel-Guides) ![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in O Brien, FL from CA $82 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in O Brien Family friendly [](https://www.expedia.ca/Hotel-Search?destination=O+Brien%2C+Florida%2C+United+States+of+America®ionId=3000431472&latLong=30.03829%2C-82.940697&adults=2&startDate=2025-11-23&d1=2025-11-23&endDate=2025-11-25&d2=2025-11-25&travelerType=family_friendly) Cabin [](https://www.expedia.ca/Hotel-Search?destination=O+Brien%2C+Florida%2C+United+States+of+America®ionId=3000431472&latLong=30.03829%2C-82.940697&adults=2&startDate=2025-11-23&d1=2025-11-23&endDate=2025-11-25&d2=2025-11-25&lodging=CABIN) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=O+Brien%2C+Florida%2C+United+States+of+America®ionId=3000431472&latLong=30.03829%2C-82.940697&adults=2&startDate=2025-11-23&d1=2025-11-23&endDate=2025-11-25&d2=2025-11-25&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=O+Brien%2C+Florida%2C+United+States+of+America®ionId=3000431472&latLong=30.03829%2C-82.940697&adults=2&startDate=2025-11-23&d1=2025-11-23&endDate=2025-11-25&d2=2025-11-25&lodging=APARTMENT) Pool [](https://www.expedia.ca/Hotel-Search?destination=O+Brien%2C+Florida%2C+United+States+of+America®ionId=3000431472&latLong=30.03829%2C-82.940697&adults=2&startDate=2025-11-23&d1=2025-11-23&endDate=2025-11-25&d2=2025-11-25&amenities=POOL) Cottage [](https://www.expedia.ca/Hotel-Search?destination=O+Brien%2C+Florida%2C+United+States+of+America®ionId=3000431472&latLong=30.03829%2C-82.940697&adults=2&startDate=2025-11-23&d1=2025-11-23&endDate=2025-11-25&d2=2025-11-25&lodging=COTTAGE) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=O+Brien%2C+Florida%2C+United+States+of+America®ionId=3000431472&latLong=30.03829%2C-82.940697&adults=2&startDate=2025-11-23&d1=2025-11-23&endDate=2025-11-25&d2=2025-11-25&amenities=PETS) ## Check prices for these dates Tonight [Nov 9 - Nov 10](https://www.expedia.ca/Hotel-Search?regionId=3000431472&startDate=2025-11-09&endDate=2025-11-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 10 - Nov 11](https://www.expedia.ca/Hotel-Search?regionId=3000431472&startDate=2025-11-10&endDate=2025-11-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000431472&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=3000431472&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 341 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Exterior](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/e851cfaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds (Walk-In Shower)](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/41c6488c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/485a2a22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/758be2b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Alachua - Gainesville Area by IHG Alachua 9.4/10 Exceptional (1007) "Room was very clean, staff friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $171 CA $193 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/c38f0eff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/b562f911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/6a43fc6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suite by Wyndham Lake City Lake City 8.8/10 Excellent (1009) "It felt very safe and my pppet was welcomed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $131 CA $148 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/540000/537200/537189/adf8855d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/540000/537200/537189/55b69a67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/540000/537200/537189/2a6768bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/540000/537200/537189/6579eaa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Alachua Alachua 4.8/10 (594) "Staff was helpful and so courteous.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian CA $81 CA $91 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Gainesville-Hotels-Americas-Best-Value-Inn-Alachua.h537189.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/a952eda0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/35661d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/847fac5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/68371972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Alachua I-75 Alachua 9.4/10 Exceptional (465) "We would definitely stay here again if we are ever in this area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KAREN CA $139 CA $157 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/a415bbca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/dc8aa87c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/fb3e9b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/f5ec1000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Lake City Lake City 9.2/10 Wonderful (1002) "It was perfect, we got in super late an was met with a quick check in an a great breakfast the next day" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aurora CA $117 CA $132 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99930000/99922700/99922616/9c441019.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/100000000/99930000/99922700/99922616/74ab7d36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/100000000/99930000/99922700/99922616/4c7d1a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/100000000/99930000/99922700/99922616/6cb67822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Lake City Lake City 9.6/10 Exceptional (165) "Nice place for a weekend trip to the springs close by.Would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $150 CA $169 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Lake-City-Hotels-Courtyard-By-Marriott-Lake-City.h99922616.Hotel-Information) ![Double Room, Non Smoking](https://images.trvl-media.com/lodging/114000000/113900000/113898600/113898531/5ff8c576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113900000/113898600/113898531/09adf73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113900000/113898600/113898531/b5e748ad_edited_617d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/114000000/113900000/113898600/113898531/1d9d9999_edited_d095.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### High Springs Country Inn High Springs 8.6/10 Excellent (13) "It was a comfortable stay for one night" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $103 CA $116 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/High-Springs-Hotels-High-Springs-Country-Inn.h113898531.Hotel-Information) ![Pillowtop beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/4977ae81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/1d6290c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/695b0a91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/70b1f0e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Lake City Lake City 9.6/10 Exceptional (1003) "Nice clean rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bethany CA $130 CA $146 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/47bbd7f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/fd7eab0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/63478939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/e1dc2812.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn White Springs Suwanee Live Oak 7.2/10 Good (602) "The room was ok (not good, not bad, just ok). The breakfast was also ok. The room was a bit small for three people." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sichao CA $76 CA $84 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Lake-City-Hotels-Quality-Inn.h1378708.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/15800/15747/590bae4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds, Non Smoking (Oversize)](https://images.trvl-media.com/lodging/1000000/20000/15800/15747/5173400f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15800/15747/de24c9b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15800/15747/98a5e0bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Lake City I-75 Lake City 5.0/10 (1002) "Friendly staff checked me in. Clean room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $81 CA $91 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Lake-City-Hotels-Baymont-By-Wyndham-Lake-City.h15747.Hotel-Information) ![Standard Cabin, 1 Queen Bed | Exterior](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/a2ef87a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/9c577e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Cabin, 2 Queen Beds | Private kitchen](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/8ad8644d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/4879ff7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy High Springs 9.8/10 Exceptional (134) "Great place to getaway. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlyson Barros CA $153 CA $230 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/High-Springs-Hotels-Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information) ![Individually decorated, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/90000/85000/84936/9948e87a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/90000/85000/84936/a71dca11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/90000/85000/84936/d4297742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/90000/85000/84936/944a276f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Lake City I-10 Lake City 6.8/10 (1001) "Was quite and clean, a little dated but it was a good place to sleep they are pet friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $84 CA $95 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Lake-City-Hotels-Days-Inn-By-Wyndham-Lake-City-I-10.h84936.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/1f67a534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/5b344087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/bfe0c823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/fad9110f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Lake City Lake City 9.2/10 Wonderful (1004) "Good hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank CA $122 CA $138 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Lake-City-Hotels-Tru-By-Hilton-Lake-City.h34865542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/9a0ddc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/00752d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/69fc9dfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/w4000h2664x0y0-4664f427.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Lake City Lake City 9.0/10 Wonderful (145) "Stay here every time I’m in town and love it. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darcy CA $138 CA $155 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Lake-City-Hotels-Fairfield-Inn-Suites-Lake-City.h2076513.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/cbec2bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/d203aab4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/2acb054a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/494a0351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Lake City Lake City 7.8/10 Good (944) "Everything was great about this property and the staff were very friendly and accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $94 CA $106 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Lake-City-Hotels-Quality-Inn-Lake-City.h484004.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/1bfc5692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/645a482b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/8ce5f9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/ad8fe69d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Lake City Lake City 8.8/10 Excellent (1006) "Great value, super polite staff, and clean, comfortable rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chelsea CA $94 CA $106 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Lake-City-Hotels-Americas-Best-Value-Inn-Lake-City.h1039754.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/1d104673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Select Comfort beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/cf4e1088.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/0b9cfe16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/45cc4db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Lake City Lake City 9.4/10 Exceptional (1003) "It was a great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miranda CA $128 CA $144 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/120000000/119610000/119606200/119606176/86b658ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119610000/119606200/119606176/9444fa12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/120000000/119610000/119606200/119606176/w3837h2160x3y0-3ebb9ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/120000000/119610000/119606200/119606176/0840ecb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 – Lake City, Fl – Medical Center Lake City 8.4/10 Very good (35) "Great little motel with extremely nice staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Georgiy CA $73 CA $82 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Lake-City-Hotels-Motel-6-Lake-City.h119606176.Hotel-Information) ![Pillowtop beds, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/eb9ba6b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/90e37569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/529b1288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/8fa5709a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Lake City I-75 Lake City 7.4/10 Good (1007) "Very clean! Very friendly staff! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marleis CA $97 CA $109 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Lake-City-Hotels-Days-Inn-By-Wyndham-Lake-City-I-75.h17650.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/88000000/87680000/87671900/87671816/4f50db02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/88000000/87680000/87671900/87671816/dffd0064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Room](https://images.trvl-media.com/lodging/88000000/87680000/87671900/87671816/fe90356d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87680000/87671900/87671816/5794d577.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### BlueGem Motel High Springs 9.2/10 Wonderful (381) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wesley CA $141 CA $159 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/High-Springs-Hotels-BlueGem-Motel.h87671816.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25®ionId=3000431472&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FO-Brien-Hotels.d3000431472.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FO-Brien-Hotels.d3000431472.Travel-Guide-Hotels) ## Learn more about O Brien Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities. [See all hotels in O Brien](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&adults=2®ionId=3000431472) ![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## More cheap stays in O Brien ![Best Western Plus Lake City](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/a415bbca_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Lake City 350 SW Florida Gateway Dr, Lake City, FL CA $117 CA $132 total Nov 16 - Nov 17 includes taxes & fees 9/10 Wonderful! (1,001 reviews) [](https://expedia.ca/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information) ![La Quinta Inn & Suite by Wyndham Lake City](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### La Quinta Inn & Suite by Wyndham Lake City 165NW CALI DRIVE, Lake City, FL CA $131 CA $148 total Dec 1 - Dec 2 includes taxes & fees 8.6/10 Excellent! (1,009 reviews) [](https://expedia.ca/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) ![Tru by Hilton Lake City](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/1f67a534_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru by Hilton Lake City 284 NW Centurion Court, Lake City, FL CA $122 CA $138 total Nov 16 - Nov 17 includes taxes & fees 9/10 Wonderful! (1,004 reviews) [](https://expedia.ca/Lake-City-Hotels-Tru-By-Hilton-Lake-City.h34865542.Hotel-Information) ![Comfort Suites Lake City](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/4977ae81_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Lake City 3690 W Us Highway 90, Lake City, FL CA $130 CA $146 total Nov 17 - Nov 18 includes taxes & fees 9.4/10 Exceptional! (1,002 reviews) [](https://expedia.ca/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) ![Holiday Inn Express & Suites Live Oak by IHG](https://images.trvl-media.com/lodging/1000000/800000/798800/798756/ddd17ce3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Live Oak by IHG 6694 Us Highway 129, Live Oak, FL CA $182 CA $200 total Nov 18 - Nov 19 includes taxes & fees 8.2/10 Very Good! (760 reviews) [](https://expedia.ca/Lake-City-Hotels-Holiday-Inn-Express-Hotel-Suites-LIVE-OAK.h798756.Hotel-Information) ![Hampton Inn & Suites Lake City](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/1d104673_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn & Suites Lake City 450 SW Florida Gateway Drive, Lake City, FL CA $128 CA $144 total Nov 16 - Nov 17 includes taxes & fees 9.4/10 Exceptional! (1,003 reviews) [](https://expedia.ca/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) ## Recent reviews of O Brien hotels ![Hampton Inn & Suites Lake City](//images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/1d104673_y.jpg) ### Hampton Inn & Suites Lake City 5/5 Excellent "Really friendly staff, good breakfast. They are doing renovations but it didn’t affect our overnight. Handy off of the hiway. " A verified traveller from Punta Gorda stayed at Hampton Inn & Suites Lake City Posted 14 hours ago [](https://expedia.ca/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) ![La Quinta Inn & Suite by Wyndham Lake City](//images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571_y.jpg) ### La Quinta Inn & Suite by Wyndham Lake City 5/5 Excellent "Fast easy check-in. Wonderfully maintained room. Bathroom was immaculate. Shower had immediate hot water. Bed was very comfortable!" A verified traveller stayed at La Quinta Inn & Suite by Wyndham Lake City Posted 14 hours ago [](https://expedia.ca/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) ![Tru by Hilton Lake City](//images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/1f67a534_y.jpg) ### Tru by Hilton Lake City 5/5 Excellent "Only thing I did t like is the dog around breakfast " A verified traveller stayed at Tru by Hilton Lake City Posted 1 day ago [](https://expedia.ca/Lake-City-Hotels-Tru-By-Hilton-Lake-City.h34865542.Hotel-Information) ![Holiday Inn & Suites Lake City by IHG](//images.trvl-media.com/lodging/2000000/1120000/1115400/1115327/5d9b579a_y.jpg) ### Holiday Inn & Suites Lake City by IHG 5/5 Excellent "Clean room and wonderful check in " A verified traveller stayed at Holiday Inn & Suites Lake City by IHG Posted 2 days ago [](https://expedia.ca/Lake-City-Hotels-Holiday-Inn-Suites-Lake-City.h1115327.Hotel-Information) ![Best Western Plus Lake City](//images.trvl-media.com/lodging/1000000/910000/901400/901396/a415bbca_y.jpg) ### Best Western Plus Lake City 5/5 Excellent "It was perfect, we got in super late an was met with a quick check in an a great breakfast the next day" A verified traveller stayed at Best Western Plus Lake City Posted 3 days ago [](https://expedia.ca/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information) ![Comfort Suites Lake City](//images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/4977ae81_y.jpg) ### Comfort Suites Lake City 5/5 Excellent "The staff was friendly and the room was spotless. " A verified traveller stayed at Comfort Suites Lake City Posted 4 days ago [](https://expedia.ca/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) ![Holiday Inn Express & Suites Alachua - Gainesville Area by IHG](//images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/e851cfaf_y.jpg) ### Holiday Inn Express & Suites Alachua - Gainesville Area by IHG 5/5 Excellent "Convenient location off 95" A verified traveller stayed at Holiday Inn Express & Suites Alachua - Gainesville Area by IHG Posted 4 days ago [](https://expedia.ca/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information) ![Americas Best Value Inn Lake City](//images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/1bfc5692_y.jpg) ### Americas Best Value Inn Lake City 5/5 Excellent "Great value, super polite staff, and clean, comfortable rooms" A verified traveller stayed at Americas Best Value Inn Lake City Posted 5 days ago [](https://expedia.ca/Lake-City-Hotels-Americas-Best-Value-Inn-Lake-City.h1039754.Hotel-Information) ![Motel 6 – Lake City, Fl – Medical Center](//images.trvl-media.com/lodging/120000000/119610000/119606200/119606176/86b658ba_y.jpg) ### Motel 6 – Lake City, Fl – Medical Center 5/5 Excellent "Property met all expectations. Would stay again." A verified traveller stayed at Motel 6 – Lake City, Fl – Medical Center Posted 6 days ago [](https://expedia.ca/Lake-City-Hotels-Motel-6-Lake-City.h119606176.Hotel-Information) ## Frequently asked questions ### When is the best time to go to O Brien? > The most popular time to visit O'Brien is July, when the town comes alive with vibrant summer activities and events. During this peak season, which spans from June to August, temperatures typically reach a pleasant average of around 22°C, making it superb for enjoying outdoor adventures and exploring the natural beauty of the area. > > > > This lively period invites travellers to immerse themselves in the local culture, with various festivals and outdoor markets that showcase the best of O'Brien's offerings. The warm weather encourages visitors to take advantage of the scenic hiking trails, refreshing lakes, and expansive parks, all of which provide a stunning backdrop for sightseeing and relaxation. > > > > If you're a couple seeking a romantic escape, July is particularly enchanting. The long days allow for leisurely strolls under the stars, and many local restaurants feature outdoor seating to enjoy a meal al fresco while soaking in the charming atmosphere. The community often hosts events that encourage socializing, superb for those wanting to connect with locals and other travellers alike. > > > > For those who want to enjoy O'Brien without the peak season hustle, consider visiting in November. While this may be a quieter time, it offers unique opportunities to experience the town's cosy charm, with fewer crowds and a chance to engage more intimately with the local culture. Plus, the cooler temperatures create a superb setting for enjoying seasonal delights, such as warm beverages and hearty local cuisine. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in O Brien. ### How can I save on a O Brien hotel booking with Expedia? > Before booking your O Brien hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a O Brien hotel? > Prices for hotels in O Brien often vary, but you can find a great deal from CA $82 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - More ways to book - [Alton Hotels](https://www.expedia.ca/Alton-Hotels.d553248635975876473.Travel-Guide-Hotels) - [Resorts in Alton](https://www.expedia.ca/Alton-Resort-Hotels.d553248635975876473-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in Bell](https://www.expedia.ca/Bell-Apart-Hotels.d3000430838-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Bell](https://www.expedia.ca/Bell-Bed-And-Breakfast.d3000430838-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Bell](https://www.expedia.ca/Bell-Hotels-Cheap-Hotels.0-0-d3000430838-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Bell](https://www.expedia.ca/Bell-Hotels-Luxury-Hotel.0-0-d3000430838-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Bell Hotels](https://www.expedia.ca/Bell-Hotels.d3000430838.Travel-Guide-Hotels) - 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