Title: The 10 Best Hotels Near North Mississippi Medical Center, Tupelo from CA $71 | Expedia.ca [Tupelo Travel Guide](https://expedia.ca/Tupelo.dx6058686)[Vacation Rentals in Tupelo](https://expedia.ca/Tupelo-Vacation-Rentals.d6058686.Travel-Guide-VacationRentals)[Flights to Tupelo](https://expedia.ca/Cheap-Flights-To-Tupelo.d6058686.Travel-Guide-Flights)[North Mississippi Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-North-Mississippi-Medical-Center.d6140198.Car-Rental-Guide)[North Mississippi Medical Center Vacations](https://expedia.ca/North-Mississippi-Medical-Center-Tupelo.d6140198.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 14 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2026-03-14&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 15 - Mar 16](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2026-03-15&endDate=2026-03-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for North Mississippi Medical Center hotels ![Restaurant](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/2dd2ec4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/5e403676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/b4b35f75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/564eab06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Tupelo, a Wyndham Hotel [](https://www.expedia.ca/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) 2.2 km from North Mississippi Medical Center 9.6/10 Exceptional (612 reviews) "Everything was great, staff, room, restaurant. Highly recommend if you are in Tupelo." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan CA $217 CA $237 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/28d227fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/8d0dca5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/a0b90111.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/c2002907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hotel & Suites Tupelo North by IHG [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) 3 km from North Mississippi Medical Center 9.2/10 Wonderful (1,000 reviews) "Room was great very nice hotel, restaurant fantastic!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hailie CA $169 CA $184 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/99907b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/5607cbfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/2ecf5fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/38bad4d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Hilton-Garden-Inn-Tupelo.h1513705.Hotel-Information) 2.3 km from North Mississippi Medical Center 8.2/10 Very good (1,001 reviews) "Excellent location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mohammad CA $134 CA $146 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Tupelo-Hotels-Hilton-Garden-Inn-Tupelo.h1513705.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/7e36aedb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/caaaf941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/87db50ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/3b120605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Tupelo North by IHG [](https://www.expedia.ca/Tupelo-Hotels-Candlewood-Suites-Tupelo-North.h5966360.Hotel-Information) 3 km from North Mississippi Medical Center 8.6/10 Excellent (445 reviews) "Once we were given a cleaned room, stay was lovely. Very clean & accommodating accaccommodating acc" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura CA $151 CA $165 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Tupelo-Hotels-Candlewood-Suites-Tupelo-North.h5966360.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/71a98cb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/41098c57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/a0411a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/aaf1c148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Tupelo North [](https://www.expedia.ca/Tupelo-Hotels-SureStay-Hotel-By-Best-Western-Tupelo-North.h3874642.Hotel-Information) 2.8 km from North Mississippi Medical Center 7.4/10 Good (245 reviews) "Tub to work. Hold water. Stopper was messed up. Have free gifts baggies for the customers " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Belinda CA $80 CA $87 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Tupelo-Hotels-SureStay-Hotel-By-Best-Western-Tupelo-North.h3874642.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/c1bb111f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/05962f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/766133a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/a4d90b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites Tupelo, MS - North [](https://www.expedia.ca/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) 3.1 km from North Mississippi Medical Center 7.4/10 Good (549 reviews) "Great owners good people " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Antonis CA $65 CA $71 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) ![Individually furnished, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/db5ef9d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/7d82dd7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/5d7c5b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/6f08dfa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Tupelo, MS - Downtown [](https://www.expedia.ca/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) 3 km from North Mississippi Medical Center 6.8/10 (284 reviews) "it is conveniently close to the interstate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet CA $79 CA $86 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/4cab39f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/284d5d0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/9a140bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/0a336343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scottish Inns [](https://www.expedia.ca/Tupelo-Hotels-Scottish-Inns.h903414.Hotel-Information) 2 km from North Mississippi Medical Center 5.6/10 (94 reviews) "Awesome beds and quite " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $82 CA $89 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Tupelo-Hotels-Scottish-Inns.h903414.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/15eb656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/6902bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/5ba41635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/9a4c9a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Tupelo by IHG [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) 4.1 km from North Mississippi Medical Center 9.4/10 Exceptional (1,000 reviews) "We have stayed here several times over the last few years, and have been very pleased with the accommodations. Clean room - helpful and friendly staff - good breakfast options. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $156 CA $171 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/263e981b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/33b16390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/272130c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/3bb6afaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) 3.6 km from North Mississippi Medical Center 8.6/10 Excellent (1,001 reviews) "The room was very clean, the staff was exceptional and the hotel is very conveniently located to restaurant." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol CA $119 CA $130 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/214586c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/06eb4d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/80f7a806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/c42a976c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) 3.6 km from North Mississippi Medical Center 8.2/10 Very good (1,005 reviews) "Room was nice and roomy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vincent CA $89 CA $97 total includes taxes & fees Apr 1 - Apr 2 [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/c0a90d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/ee19c8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/7f7b6e74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/4b9db4c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Tupelo, Ms [](https://www.expedia.ca/Tupelo-Hotels-Home2-Suites-By-Hilton-Tupelo.h70048190.Hotel-Information) 4.3 km from North Mississippi Medical Center 9.4/10 Exceptional (393 reviews) "My entire stay was wonderful.. I will most definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LaJaysha CA $153 CA $167 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Tupelo-Hotels-Home2-Suites-By-Hilton-Tupelo.h70048190.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/50d63d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/ceef32e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/46ee23a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/eda0cd99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) 4.3 km from North Mississippi Medical Center 9.2/10 Wonderful (686 reviews) "Clean, easy check-in, good area with dining options close." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suzette CA $126 CA $137 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/974b178f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/1216ed7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/a4d5cce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/e6ce0f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Tupelo Central [](https://www.expedia.ca/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) 3.6 km from North Mississippi Medical Center 8.2/10 Very good (1,000 reviews) "Good value for price compared to area. Friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regan CA $98 CA $107 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/93da9926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/5ffbc4f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/14fa7bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/dcc3bdc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Courtyard-By-Marriott-Tupelo.h42285.Hotel-Information) 3.9 km from North Mississippi Medical Center 8.4/10 Very good (314 reviews) "Good experience, will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lamont CA $165 CA $181 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Tupelo-Hotels-Courtyard-By-Marriott-Tupelo.h42285.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/a4930614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/2660a6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/888d81ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/786994c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Tupelo Central [](https://www.expedia.ca/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) 4 km from North Mississippi Medical Center 7.8/10 Good (541 reviews) "Great hot breakfasts with homemade eggs and potatoes " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $86 CA $94 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) ![Presidential Studio Suite, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/db91ffba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/w2999h2000x0y0-850de2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 11:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/97b5a707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/f84f5240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) 4.2 km from North Mississippi Medical Center 7.6/10 Good (1,001 reviews) "The rooms where clean and the staff was nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandi CA $89 CA $97 total includes taxes & fees Apr 13 - Apr 14 [](https://www.expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/b694ac45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/329e3e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/2d49d2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/f6b80560.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Days-Inn-By-Wyndham-Tupelo.h23221.Hotel-Information) 3.6 km from North Mississippi Medical Center 6.8/10 (367 reviews) "Great place to say everyone was friendly and very close to all the sites" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Piper CA $78 CA $85 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Tupelo-Hotels-Days-Inn-By-Wyndham-Tupelo.h23221.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/f27f3041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/53543e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/3f1f0515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Tupelo Inn & Suites [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) 6.3 km from North Mississippi Medical Center 8.8/10 Excellent (1,003 reviews) "The Room was very clean and the staff was friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chloe CA $127 CA $139 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/6524fbce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/cc405a28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/0cf1b94f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/27ebce81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Tupelo Barnes Crossing [](https://www.expedia.ca/Tupelo-Hotels-Econolodge-Tupelo.h539490.Hotel-Information) 7 km from North Mississippi Medical Center 6.6/10 (393 reviews) "Clean room. Good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $77 CA $84 total includes taxes & fees Mar 23 - Mar 24 [](https://www.expedia.ca/Tupelo-Hotels-Econolodge-Tupelo.h539490.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-28&endDate=2026-03-29®ionId=6140198&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top North Mississippi Medical Center Hotel Reviews ![Studio 6 Suites Tupelo, MS - North](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/c1bb111f_y.jpg) ### Studio 6 Suites Tupelo, MS - North 2/10 Terrible "Starting out the woman caught an attitude with me like I was bothering her with the questions that I had. For a single woman, parking was very very shady very dark on the side I was told to park on. The building smelled horrible walking in. The mini fridge in my room didn’t work & it had a terrible odor coming from the inside when you opened the fridge door. Just feel like they could care more. " [](https://expedia.ca/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) ![Tru By Hilton Tupelo](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/50d63d1c_y.jpg) ### Tru By Hilton Tupelo 10/10 Excellent "Hotel was very nice and clean. The breakfast was also better than most hotels. Enjoyed our stay." [](https://expedia.ca/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) ![Red Roof Inn Tupelo](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/214586c5_y.jpg) ### Red Roof Inn Tupelo 8/10 Good "Clean, good facilities, convenient location, limited breakfast." [](https://expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) ![Best Western Plus Tupelo Inn & Suites](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9_y.jpg) ### Best Western Plus Tupelo Inn & Suites 6/10 Okay "We had a king suite on the ground floor. It was a little windy and when the heat was not running the unit would whistle waking us up multiple times in the night. At 4:15 am, we went to the front desk. The night clerk came down but could not do anything about the whistle and had no spare rooms to offer. The solution was to turn up the heat so the register would run and avoid the noise." [](https://expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ![Quality Inn Tupelo Central](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/a4930614_y.jpg) ### Quality Inn Tupelo Central 10/10 Excellent "Very comfortable bed. Met our needs for the night." [](https://expedia.ca/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) ![Holiday Inn Hotel & Suites Tupelo North by IHG](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/28d227fa_y.jpg) ### Holiday Inn Hotel & Suites Tupelo North by IHG 10/10 Excellent "Clean, nice hotel, staff very friendly " [](https://expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ![Baymont by Wyndham Tupelo](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/db91ffba_y.jpg) ### Baymont by Wyndham Tupelo 6/10 Okay "Pool was extremely cloudy, I wouldn't have consideted using it. The bathroom tub was not clean and bloid like substance on bathroom door and wall. Aircoditioner looked filthy and smelled musty. Breakfast was lack luster." [](https://expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tupelo](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/263e981b_y.jpg) ### La Quinta Inn & Suites by Wyndham Tupelo 6/10 Okay "There was an odd stain in the bathtub but otherwise the room was clean. The pool is outdoors and was closed. Breakfast was limited but ok enough to start the day. " [](https://expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Motel 6 Tupelo, MS - Downtown](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/db5ef9d5_y.jpg) ### Motel 6 Tupelo, MS - Downtown 6/10 Okay "Clean & staff was great" [](https://expedia.ca/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) ## Hotels near other North Mississippi Medical Center attractions ### Tupelo Buffalo Park 4.0/5 (71 reviews) Why not see the exotic and native animals who live at Tupelo Buffalo Park during your travels in Tupelo? Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655102) ### Tupelo National Battlefield 3.8/5 (66 reviews) Explore the great outdoors at Tupelo National Battlefield, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092633) ### BancorpSouth Arena 4.3/5 (151 reviews) Catch an event at BancorpSouth Arena during your trip to Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092629) ### Rob Leake City Park Tennis Center Catch an event at Rob Leake City Park Tennis Center during your trip to Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624716639272960) ### Ballard Park 4.2/5 (110 reviews) Explore the great outdoors at Ballard Park, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655097) ### Elvis Presley Center 4.2/5 (168 reviews) You can spend time studying the exhibits at Elvis Presley Center during your travels in Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655101) ### Oren Dunn City Museum 3.7/5 (19 reviews) You can spend time studying the exhibits at Oren Dunn City Museum during your trip to Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655096) ### Elvis Presley Lake and Campground 4.1/5 (51 reviews) Explore the great outdoors at Elvis Presley Lake and Campground, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655103) ## Frequently asked questions ### What's the area like around North Mississippi Medical Center? ### What's the best hotel to stay close to North Mississippi Medical Center? ### How many hotels are there near North Mississippi Medical Center? ### If I need to cancel the hotel reservation for my stay near North Mississippi Medical Center, will I receive a refund? ### What can I see and do near North Mississippi Medical Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Aberdeen Hotels ](https://www.expedia.ca/Aberdeen-Hotels.d10650.Travel-Guide-Hotels) - [Amory Hotels ](https://www.expedia.ca/Amory-Hotels.d183443.Travel-Guide-Hotels) - [Anchor Hotels ](https://www.expedia.ca/Anchor-Hotels.d553248635975848560.Travel-Guide-Hotels) - [Hotels near BancorpSouth Arena ](https://www.expedia.ca/BancorpSouth-Arena-Hotels.0-l6092629-0.Travel-Guide-Filter-Hotels) - 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