Title: Book the Best Northwest San Antonio LUXURY Hotels - Upscale Hotels in Northwest San Antonio, TX | Expedia.ca [Northwest San Antonio Travel Guide](https://expedia.ca/Northwest-San-Antonio.dx6059170)[Hotels in Northwest San Antonio](https://expedia.ca/Northwest-San-Antonio-Hotels.d6059170.Travel-Guide-Hotels)[Vacation Rentals in Northwest San Antonio](https://expedia.ca/Northwest-San-Antonio-Vacation-Rentals.d6059170.Travel-Guide-VacationRentals)[Flights to Northwest San Antonio](https://expedia.ca/Cheap-Flights-To-Northwest-San-Antonio.d6059170.Travel-Guide-Flights)[Things to do in Northwest San Antonio](https://expedia.ca/Things-To-Do-In-Northwest-San-Antonio.d6059170.Travel-Guide-Activities)[Northwest San Antonio Car Rentals](https://expedia.ca/Car-Rentals-In-Northwest-San-Antonio.d6059170.Car-Rental-Guide)[Northwest San Antonio Vacation Packages](https://expedia.ca/Northwest-San-Antonio.d6059170.Destination-Travel-Guides) ![Friedrich Wilderness Park featuring forest scenes, landscape views and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/24000/24287-Friedrich-Wilderness-Park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Northwest San Antonio, TX ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Northwest San Antonio Luxury Hotels Tonight [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2025-10-17&endDate=2025-10-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2025-10-18&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Northwest San Antonio Luxury Hotels ![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/08a9974f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/b2a759c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/w1852h1922x514y0-00d4306c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/fa6b231c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort La Cantera District 8.6/10 Excellent (1005) "Beautiful resort! And excellent wait staff! Loved the pool! " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Robin CA $181 CA $255 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2557x0y3-7a64bf70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2155x0y3-ce16cbd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w2684h3837x3y3-55946881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3837h2549x3y3-a19f857c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Signia by Hilton La Cantera Resort & Spa La Cantera District 9.0/10 Wonderful (1032) "Great stay new hotel huge family friendly " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane CA $450 CA $611 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Antonio-Hotels-Signia-By-Hilton-La-Cantera-Resort-Spa.h284306.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 18.95 per person)](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/f65c9ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/533974de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/4baf38da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Antonio North Vance Jackson 8.4/10 Very good (1136) "Great place to stay! " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $115 CA $138 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a92bc437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/eeb532f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast on weekdays](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/26f8671b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG Northwest Side 7.8/10 Good (1014) "Great stay" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Andres CA $128 CA $151 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/a7c3617d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/065f54d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/ec04d75a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/8e330921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites at Six Flags Northwest Side 7.8/10 Good (1007) "Nice pool and hot tub. " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Elijah CA $81 CA $94 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Antonio-Hotels-Sleep-Inn-Suites-At-Six-Flags.h2220322.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/81c3856b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jetted tub](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/1dc39474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/67193bbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/5a0d6e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham San Antonio/NW Medical Center Balcones Heights 6.8/10 (1002) [](https://www.expedia.ca/San-Antonio-Hotels-Howard-Johnson-By-Wyndham-San-AntonioNW-Medical-Center.h1465404.Hotel-Information) ![Pillowtop beds, in-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/9e3e8920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/16d41ec1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/d3db9a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/a9438006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark By Hilton San Antonio Northwest near Six Flags La Cantera District 7.8/10 Good (1664) "Nice place to stay " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) louis CA $83 CA $99 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/d27582bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/960685eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/1dc90272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/8e398b61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Inn & Suites San Antonio Northwest Side 7.2/10 Good (1000) "GREAT staff at a SAFE and CLEAN place. The beds are comfy but items are a little worn and our tub didn't drain well after each shower. Solid place to stay if you’re on a budget and need to be in and out." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $78 CA $92 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Antonio-Hotels-University-Inn-Suites-San-Antonio.h1174009.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/ded9f09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/8fcc83d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/bf8ffe69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW Medical Center District 8.6/10 Excellent (3024) "We always enjoy our stay at this hotel. The staff are always friendly, premises clean, and breakfast is great! " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Armand CA $125 CA $147 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/a0112e8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/4d5fc04e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/7260012e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/46feed1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn By Wyndham IH-10 West San Antonio TX Northwest Los Angeles Heights 6.2/10 (1007) "Love staying there" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Ana CA $76 CA $90 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-By-Wyndham-San-Antonio-Vance-Jackson.h20296.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=6059170&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Northwest San Antonio Hotel Reviews ![Spark by Hilton San Antonio Dominion](//images.trvl-media.com/lodging/3000000/2300000/2292900/2292838/f50e6891_y.jpg) ### Spark by Hilton San Antonio Dominion 10/10 Excellent "Room was clean" [](https://expedia.ca/San-Antonio-Hotels-Spark-By-Hilton-San-Antonio-Dominion.h2292838.Hotel-Information) ![Drury Inn & Suites Near La Cantera Parkway](//images.trvl-media.com/lodging/3000000/2190000/2180400/2180355/aaf7f28d_y.jpg) ### Drury Inn & Suites Near La Cantera Parkway 10/10 Excellent "We’ve stayed here a couple times and both times were great. The only issue is the construction going on (which is not the fault of the hotel). We stayed here because it is very close to Six Flags Fiesta Texas. They have an excellent breakfast as well as evening food and drinks. The hotel is clean and the staff is nice. We will definitely stay here again the next time we visit Six Flags." [](https://expedia.ca/San-Antonio-Hotels-Drury-Inn-Suites-Near-La-Cantera-Parkway.h2180355.Hotel-Information) ![Spark By Hilton San Antonio Northwest near Six Flags](//images.trvl-media.com/lodging/1000000/50000/41300/41271/9e3e8920_y.jpg) ### Spark By Hilton San Antonio Northwest near Six Flags 10/10 Excellent "It was clean and nice although the bathroom seem to have already some wear to it and the tub was very slippery. We enjoyed our stay overall" [](https://expedia.ca/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information) ![The Westin San Antonio North](//images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6_y.jpg) ### The Westin San Antonio North 10/10 Excellent "There were multiple venues going on at the same time which made for hectic and entertaining times at the hotel A Pokémon branch of comicon was surreal until I found out what was going on. Previous stays were more sedate as one would expect in primarily business oriented hotel. It is convenient to just about any place you want to see but getting onto I 10 requires a learning curve if you drive. Parking fee with no valet service was a disappointment. " [](https://expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information) ![Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG](//images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f_y.jpg) ### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG 10/10 Excellent "Great stay" [](https://expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information) ![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](//images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae_y.jpg) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW 10/10 Excellent "Exlente servicio " [](https://expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![Best Western Medical Center North Inn & Suites Near Six Flags](//images.trvl-media.com/lodging/2000000/1350000/1348700/1348602/cafc73cd_y.jpg) ### Best Western Medical Center North Inn & Suites Near Six Flags 10/10 Excellent "Beautiful " [](https://expedia.ca/San-Antonio-Hotels-Best-Western-Medical-Center-North-Inn-Suites-Near-Six-Flags.h1348602.Hotel-Information) ![Holiday Inn Express & Suites San Antonio NW - Medical Area by IHG](//images.trvl-media.com/lodging/3000000/2240000/2233300/2233206/39a575ab_y.jpg) ### Holiday Inn Express & Suites San Antonio NW - Medical Area by IHG 10/10 Excellent "Great room" [](https://expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-NW-Medical-Area.h2233206.Hotel-Information) ![Signia by Hilton La Cantera Resort & Spa](//images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2557x0y3-7a64bf70_y.jpg) ### Signia by Hilton La Cantera Resort & Spa 10/10 Excellent "It was a short trip every staff member was beyond helpful and sweet and just very, very nice. Can’t say enough about the staff from the check-in experience to the valet to the spa. Everything was exceptional." 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[Cheap Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Cheap-Hotels.0-n887264728595001344-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Family-Hotel.0-n887264728595001344-0-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Hotels-With-Free-Airport-Shuttle.0-n887264728595001344-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Hotels-With-Kitchenettes.0-n887264728595001344-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Pet-Friendly-Hotel.0-n887264728595001344-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Northwest Side](https://www.expedia.ca/Northwest-Side-San-Antonio-Hotels-Spa-Hotel.0-n887264728595001344-0-tSpaHotel.Travel-Guide-Filter-Hotels) - 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[Car rentals near Shavano Park](https://www.expedia.ca/Car-Rentals-In-Shavano-Park.d6004947.Car-Rental-Guide) - [Car rentals near The Shops of La Cantera](https://www.expedia.ca/Car-Rentals-In-The-Shops-Of-La-Cantera.d6127199.Car-Rental-Guide) - [Car rentals near USAA Corporate Office Headquarters](https://www.expedia.ca/Car-Rentals-In-USAA-Corporate-Office-Headquarters.d553248621593511346.Car-Rental-Guide) - [Book Luxury Hotels in Northwest San Antonio on Expedia.com](https://www.expedia.com/Northwest-San-Antonio-Hotels-Luxury-Hotel.0-0-d6059170-tLuxuryHotel.Travel-Guide-Filter-Hotels)