Upstate South Carolina Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

Photo by Victoria S

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

Top Upstate South Carolina Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Hartness

Hotel Hartness

4 out of 5
Price was CA $1,386, price is now CA $1,022 per person
CA $1,022
per person
Oct 2 - Oct 6
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Greenville (GSP)
9.8/10 Exceptional! (577 reviews)
Hotel grounds are beautiful with good trails nearby. Beds are very comfortable, room is nice. Breakfast was OK, but for an upscale hotel, the breakfast should also be more upscale. Staff is very friendly and accommodating.

Reviewed on Aug. 18, 2025

Zelda Dearest

Zelda Dearest

3.5 out of 5
Downtown Asheville
Price was CA $2,042, price is now CA $1,402 per person
CA $1,402
per person
Sep 25 - Sep 29
found 17 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Asheville (AVL)
10/10 Exceptional! (196 reviews)
Zelda Dearest is a stylish art deco retreat with excellent service, attention to every detail and central location. Will stay there again and definitely recommend to friends!

Reviewed on Aug. 18, 2025

The Restoration Asheville

The Restoration Asheville

4 out of 5
Downtown Asheville
Price was CA $2,282, price is now CA $1,620 per person
CA $1,620
per person
Sep 25 - Sep 29
found 17 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Asheville (AVL)
9.8/10 Exceptional! (895 reviews)
The property is beautiful and clean. Service is excellent. I would stay here again.

Reviewed on Aug. 21, 2025

Bluegreen Vacations Blue Ridge Village an Ascend Resort

Bluegreen Vacations Blue Ridge Village an Ascend Resort

3 out of 5
Price was CA $1,737, price is now CA $1,291 per person
CA $1,291
per person
Oct 11 - Oct 18
found 1 hour ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asheville (AVL)
9.2/10 Wonderful! (865 reviews)
Great places to stay with good amenities and close to grandfather Mountain

Reviewed on Aug. 22, 2025

Hilton Garden Inn Asheville Downtown

Hilton Garden Inn Asheville Downtown

3 out of 5
Downtown Asheville
Price was CA $1,539, price is now CA $1,163 per person
CA $1,163
per person
Sep 25 - Sep 29
found 17 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Asheville (AVL)
9.2/10 Wonderful! (856 reviews)
Walking distance to downtown was very convenient.

Reviewed on Aug. 21, 2025

Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville which includes autumn leaves, a garden and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area
5/5(3 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Ready to book your vacation to Upstate South Carolina?

 

Choose your dates

Upstate South Carolina Hotel Deals

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
The price is CA $131 per night from Aug 31 to Sep 1
CA $131
CA $144 total
Aug 31 - Sep 1
includes taxes & fees
8.4/10 Very Good! (1,000 reviews)
"Great hotel , would stay again ."

Reviewed on Aug. 16, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $187 per night from Sep 1 to Sep 2
CA $187
CA $211 total
Sep 1 - Sep 2
includes taxes & fees
8.6/10 Excellent! (1,002 reviews)
"great"

Reviewed on Aug. 21, 2025

Hyatt Regency Greenville
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Sep 4 to Sep 5
CA $121
CA $137 total
Sep 4 - Sep 5
includes taxes & fees
8/10 Very Good! (1,000 reviews)
"Todo perfecto"

Reviewed on Aug. 19, 2025

Hilton Greenville
See all 2,790 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Upstate South Carolina

Fred W. Symmes Chapel

Fred W. Symmes Chapel

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

Fred W. Symmes Chapel

Greenville Convention Center

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

Greenville Convention Center

Wofford College

Take a campus tour or just explore the area of Wofford College, during your trip to Spartanburg. Experience the area's theater scene or attend a sporting event.

Wofford College

What to do in Upstate South Carolina

Just Desserts Tour In Greenville

Just Desserts Tour In Greenville

CA $110
per adult
Just Desserts Tour In Greenville
Paranormal Walking Tour by Greenville Ghost Tours

Paranormal Walking Tour by Greenville Ghost Tours

CA $48
per adult
Paranormal Walking Tour by Greenville Ghost Tours
Delicious breakfast on a sunny Saturday morning on the terrace

Small-Group Walking Tour in Greenville with Breakfast

CA $110
per adult
100% of travellers recommend
Small-Group Walking Tour in Greenville with Breakfast
See all activities in Upstate South Carolina

Frequently asked questions

How much does a Upstate South Carolina vacation package cost?
From as low as CA $1,022. Yes, you read that right. Our Upstate South Carolina vacation packages are the best way to stretch your budget. Bundle your preferred hotels, flights and rental car and get to know this top destination.
How do I get a cheap travel package to Upstate South Carolina?
Our Upstate South Carolina vacation packages mean plenty of savings for the savvy explorer. For the best deal, simply combine your hotel, flights and extras (such as activities) into one neat package. But great bargains are only the start of your next awesome adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotels around the world to choose from. No matter your style, there's a package with your name on it.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the key things that draws people to Upstate South Carolina, so it makes perfect sense that many opt to stay in Greenville.
What are the top hotels in Upstate South Carolina?
When it comes to hotels in Greenville, Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall are two terrific options. If you're heading to Seneca, Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson will make you feel at home.
How far in advance should I book my Upstate South Carolina vacation?
While prices fluctuate, we generally suggest booking your seats as soon as possible. Most international airfares are available on Expedia up to 12 months in advance. If circumstances have left you booking late, you might still be in luck. Cheap journeys to Upstate South Carolina occasionally appear just weeks before departure.
What does an Expedia Upstate South Carolina travel package include?
With Expedia, you can choose any combination of flights, hotels and car rentals to build your ideal Upstate South Carolina travel package. Once you've made your booking, you can add on the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the more dollars you'll save!
What should I know before booking a Upstate South Carolina travel package?
Design deals that suit your budget with an Expedia package. Hotels, flights, rental cars — we're a one-stop shop for all of them. You'll save big bucks just by bundling your bookings. Whether you're embarking on an adventure in the snow or getting some sun on a warm beach, your dream getaway is just a few clicks away.
Can I choose my airline with a Upstate South Carolina Expedia vacation package?
Yes — that's one of the best things about an Expedia vacation package. You can mix and match your flights, hotels and more. We have more than 550 airline partners throughout the world, so you have lots of choice when putting together your Upstate South Carolina getaway.
If I'm not able to travel, can I cancel my Upstate South Carolina vacation package?
Yes, you can cancel your Upstate South Carolina booking if your plans have changed. Whether you'll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.