Title: Upstate South Carolina Vacation Home Rentals : Search Top Private Vacation Homes for Rent | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Upstate South Carolina Vacation Rentals - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-05&endDate=2025-12-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-16&endDate=2026-01-18&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-02-13&endDate=2026-02-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Upstate South Carolina Vacation Homes ![Interior](https://images.trvl-media.com/lodging/119000000/118820000/118815400/118815388/9ffe4116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/119000000/118820000/118815400/118815388/93726eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118820000/118815400/118815388/5ffceeb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118820000/118815400/118815388/ee3234b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Greer 10/10 Exceptional (3) "House was perfect for our needs. Spacious and clean. Easy to access, good parking and good communication with host. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher A. CA $190 CA $501 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Greer-Hotels-Cozy.h118815388.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103660000/103650800/103650728/cf68dd1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103660000/103650800/103650728/a74b7a7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103660000/103650800/103650728/d4bb9ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103660000/103650800/103650728/36946276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Greenville 10/10 Exceptional (2) "delightful house on a very mellow street. super easy access to downtown, a grocery store close, beautiful backyard for the dog, lovely kitchen. i was in town for my anniversary week and my partner and i enjoyed the stay very much. hosts were helpful and communicative, the house was exactly as described and we literally had zero issues. i have no problem recommending this house strongly! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jon b. CA $124 CA $316 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Greenville-Hotels-Cozy-2BR-Near-Furman-Downtown.h103650728.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/bba31fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/8a1c1825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/47e75beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/e586ef9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in cleveland 9.6/10 Exceptional (7) "The place is awesome! I don’t usually leave comments but this place is worth the visit." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $140 CA $471 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Cleveland-Hotels-Secluded-Yurt-Hideaway-10-Min-To-Table-Rock.h109860449.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121860000/121856300/121856258/0683cd7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121860000/121856300/121856258/bbc795a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121860000/121856300/121856258/4727f361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121860000/121856300/121856258/556b5234.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Woodside Cotton Mill Village Historic District 10/10 Exceptional (1) "Check-in was smooth as could, be. The place itself was spotless, clean, and perfect for our stay. Highly recommend Old Europe for coffee and a pastry nearby. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew K. CA $85 CA $257 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Greenville-Hotels-Skyline-Split-A-Retreat-Close-To-Everything-You-NeedQuiet.h121856258.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/ff8281c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/ec7d22d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/88b08b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/370e1a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Woodside Cotton Mill Village Historic District 9.8/10 Exceptional (80) "Thand comfortable e bungalow was great ,clean,updated " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $104 CA $277 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greenville-Hotels-The-Blue-Bungalow-By-Unity-Park-Newly-Renovated.h78137271.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/103000000/102560000/102556800/102556795/2a6de4fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/103000000/102560000/102556800/102556795/88a4e2c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/103000000/102560000/102556800/102556795/a5600f05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining tables](https://images.trvl-media.com/lodging/103000000/102560000/102556800/102556795/818ad6ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Greenville 9.6/10 Exceptional (4) "Great for our visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert B. CA $124 CA $414 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Greenville-Hotels-Chic-3BR-Home-Pet-Friendly.h102556795.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/69a716cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/1242abd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, toilet paper](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/9a3533de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/37f54e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Greenville 10/10 Exceptional (11) "It was clean and quiet..I will stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly S. CA $127 CA $233 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greenville-Hotels-Apt-Near-Downtown-Greenville.h77937495.Hotel-Information) ![Smart TV, video games, Netflix, streaming services](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/a93dcf1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/16b6d6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, Netflix, streaming services](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/17e600ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/7fb74463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Gaffney 9.6/10 Exceptional (29) "This property was in a perfect place for what we needed. We felt safe and the house was clean! We will definitely be back next year when we are attending camp! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tessa S. CA $140 CA $319 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Gaffney-Hotels-Cozy-2-Bedroom-Home-Near-Downtown-Gaffney.h87135240.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/b7a1f289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/7411cba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/de9f5026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball, books](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/d57b249b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Pickens 9.8/10 Exceptional (30) "We enjoyed our stay at this lovely home! Checking was easy and kitchen was roomy and met our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla B. CA $152 CA $371 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/e38cd5c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/63e64e17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/7fc0df84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, dishwasher](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/eb73e0bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Cleveland 10/10 Exceptional (1) "Accurate listing, easy to find! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth T. CA $116 CA $371 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Cleveland-Hotels-Pet-Friendly-Cabin-In-Marietta-W-Porch-Swings.h102557173.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/f3b8854d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/611292d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/a1094559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/74751811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Pendleton 10/10 Exceptional (3) "Clean and comfortable. Close to campus" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russ C. CA $176 CA $566 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Pendleton-Hotels-Charming-3-Bedroom-House-In-Pendleton-With-AC.h113518324.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697517/w768h573x0y3-cb3d4b73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697517/93bd266d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697517/e6317a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697517/a9a07c75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Clemson 10/10 Exceptional (1) "Adorable cottage house in prime location. Great location within minutes of university and restaurants. Host was easy to work with and communicated well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex M. CA $775 CA $1,251 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Charming-2-Bedroom-House-In-Clemson-4mi-From-Death-Valley-And-1mi-From-Macs.h119697517.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/ca5e0e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/38a9f184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/dc675269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/0ebefea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Marietta 10/10 Exceptional (50) "Very well appointed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara P. CA $102 CA $228 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Marietta-Hotels-Hobbit-Hideaway-Do-Something-Different.h78175602.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/b04bd3c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/4ada4bf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/a902f25a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/333b582b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Greenville 9.6/10 Exceptional (110) "Very cute and clean. The yard was great for the dogs. Kitchen wa nicely stocked. Many amenities. Was a nice home away from home for an extended stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen M. CA $211 CA $442 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Greenville-Hotels-Private.h73974359.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/134a8147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/0e18a612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/b6f2f270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/80400165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Pickens 10/10 Exceptional (1) "The owner quickly responded to all questions and gave access information the day before we arrived.All information was accurate. Never saw any bears, but did see a skunk in the yard one evening. So we got to see wildlife :-)Photo of beautiful sunset clouds from the porch." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janmic M. CA $113 CA $318 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Pickens-Hotels-Black-Bear-Hideaway.h120648317.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/ae5e5fc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/bf692c18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/f9b15e2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/810d8862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Greenville 10/10 Exceptional (5) "The place was perfect! Had everything we needed and was extremely clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew S. CA $140 CA $431 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Greenville-Hotels-Family-Friendly-32-Home-Near-Prisma.h103644605.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/27d2c52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/c3e07b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/455a379a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/bb5d7201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Easley 7.6/10 Good (5) "The house was great for our one night stay. The house was clean and stocked. We had to leave early and didn't spend the entire night. But the host was gracious and easy to communicate with. Would recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CANDY B. CA $126 CA $335 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Easley-Hotels-Downtown-Easley-Home.h102137027.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115980000/115971000/115970996/846586ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/116000000/115980000/115971000/115970996/b93559a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115980000/115971000/115970996/17cc8b23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115980000/115971000/115970996/7d25d0bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Easley 10/10 Exceptional (1) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) tracy CA $208 CA $441 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Easley-Hotels-Magical-Plant-Based-Loft-Downtown-Easley-Near-Silos-And-Doodle-Trail.h115970996.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111070000/111063700/111063678/abaf5b22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111070000/111063700/111063678/41241154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111070000/111063700/111063678/14e60b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111070000/111063700/111063678/c60a3b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Travelers Rest 10/10 Exceptional (15) "Great location, clean place, great communication would come back again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff S. CA $190 CA $499 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Travelers-Rest-Hotels-Spacious-4-Bedroom-Home-In-Charming-Travelers-Rest-With-WiFi-Firepit.h111063678.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/115000000/114850000/114847900/114847807/46f50cb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114850000/114847900/114847807/bb8c51e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/115000000/114850000/114847900/114847807/c78acbaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114850000/114847900/114847807/89f4694c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Pickens 10/10 Exceptional (16) "Beautiful home and all the little niceties made for a lovely stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason E. CA $254 CA $322 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Pickens-Hotels-Renewal-Rock-Vacation-Rental.h114847807.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-06&endDate=2025-12-07®ionId=6057939&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AA_BF_PROMO_6057939) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Private-Vacation-Homes.d6057939-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Private-Vacation-Homes.d6057939-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Upstate South Carolina Hotel Reviews ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Great team of people!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Great hotel" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Comfort Inn & Suites Clemson - University Area](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20_y.jpg) ### Comfort Inn & Suites Clemson - University Area 10/10 Excellent "Great stay and convenient location. " [](https://expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Everything was great will definitely be back!" [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Beautiful hotel with a bar/restaurant on the roof. Great view over the river. Convenient. I highly recommend." [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Ac was great. Room was clean. Bed was very comfortable. Really enjoyed our stay. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg) ### ECHO Suites Extended Stay by Wyndham Spartanburg 10/10 Excellent "everything seemed brand new at this hotel. book a room with confidence " [](https://expedia.ca/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Staff was very friendly. Had a really cool Nescafe machine in the breakfast area that makes lots of different coffees (mocha, latte, espresso, regular, ect)." [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Best Western Greenville Airport Inn](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f_y.jpg) ### Best Western Greenville Airport Inn 10/10 Excellent "Good all around the board" [](https://expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ## Find out more about Upstate South Carolina ## Upstate South Carolina Vacation Homes information | Number of reviews | | | --- | --- | | Accommodation | Vacation Homes | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels near Donaldson Center](https://www.expedia.ca/Donaldson-Center-Airport-Hotels.0-aGDC-0.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Gantt](https://www.expedia.ca/Gantt-Hotels-Hotels-With-Smoking-Rooms.0-0-d553248634999376437-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - 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Airport (EWR) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ewr/gdc/newark-liberty-intl-airport-to-greenville) - [Flights from Rome (FCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/fco/gdc/rome-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/gkt/gdc/gatlinburg-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GMU)](https://www.expedia.ca/lp/flights/gkt/gmu/gatlinburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/grd/gdc/greenwood-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.ca/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Huntsville (HSV) to Greenville (GMU)](https://www.expedia.ca/lp/flights/hsv/gmu/huntsville-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.ca/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jax/gmu/jacksonville-to-greenville) - 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[7th Inning Splash Waterpark](https://www.expedia.ca/7th-Inning-Splash-Waterpark-Piedmont.d553248621532656702.Vacation-Attraction) - [Central Vacations](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides) - [Discovery Island Water Park](https://www.expedia.ca/Discovery-Island-Water-Park-Greenville.d553248621532656705.Vacation-Attraction) - [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Mauldin Vacations](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides) - [Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction) - [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide) - 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