Title: Hotels by Motel 6 in Upstate South Carolina from CA $76 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![I was surprised to see this waterfall in the middle of the city! #parks #nature #southcarolina #waterfall](https://images.trvl-media.com/place/1388/fb367afc-81f4-43d0-8f61-0b0f8e73a9aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by HTN ![](https://images.trvl-media.com/place/1388/fb367afc-81f4-43d0-8f61-0b0f8e73a9aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 25 - Jan 26](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-25&endDate=2026-01-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 26 - Jan 27](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-26&endDate=2026-01-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina Motel 6 ![Fridge, microwave, freezer](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/af5363f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/c8858fa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/a86493e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/b40fcbc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Greenville, SC [](https://www.expedia.ca/Greenville-Hotels-Motel-6-Greenville.h1107497.Hotel-Information) Greenville 5.2/10 (755 reviews) " staff was amazingly friendly and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $66 CA $76 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Greenville-Hotels-Motel-6-Greenville.h1107497.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/6f7f191d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/ca766313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/60a1e95b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/1a7618f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Greenville, SC - I-85 Near Downtown [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Motel-6-Greenville.h36824597.Hotel-Information) Greenville 7.0/10 Good (388 reviews) "I always get what i need from the front desk nice people" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kyerrah CA $79 CA $87 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Motel-6-Greenville.h36824597.Hotel-Information) ![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/38900136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/dca35443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/8642cc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels, soap, toilet paper](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/c27c9604.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Spartanburg, Sc – Northwest / Business 85 [](https://www.expedia.ca/Spartanburg-Hotels-Motel-6-Spartanburg.h103059155.Hotel-Information) Spartanburg 7.2/10 Good (73 reviews) "Old building. Not well kept. Piles of dog poop everywhere. Holes in the sheets. It was basic shelter. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger CA $105 CA $117 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Spartanburg-Hotels-Motel-6-Spartanburg.h103059155.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/085635e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/72df220e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/837914fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/c5eede06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Simpsonville, SC - Greenville [](https://www.expedia.ca/Simpsonville-Hotels-Motel-6-Simpsonville.h328810.Hotel-Information) Simpsonville 7.4/10 Good (360 reviews) "Helpful and nice staff, convenient location off the interstate. Decent room for the price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin CA $110 CA $121 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Simpsonville-Hotels-Motel-6-Simpsonville.h328810.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-08&endDate=2026-02-09®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Motel-6.0-0-d6057939--bMotel6.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Motel-6.0-0-d6057939--bMotel6.Travel-Guide-Filter-Hotels) ## Top Upstate South Carolina Hotel Reviews ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Everything was up to par " [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent ":Perfect " [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Friendly staff and comfortable room " [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Would definitely stay here again. Was an amazing hotel." [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Place is very" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Breakfast was fresh. Place was clean and had a nice stay. " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "The room was amazing, the amenities were top notch, I've just gotta find a reason to come back!" [](https://expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Hampton Inn & Suites Greenville-Downtown-RiverPlace](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989_y.jpg) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace 10/10 Excellent "On site covered parking, especially if it is valet" [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![Fairfield Inn by Marriott Greenville-Spartanburg Airport](https://images.trvl-media.com/lodging/1000000/70000/67800/67753/97563107_y.jpg) ### Fairfield Inn by Marriott Greenville-Spartanburg Airport 10/10 Excellent "Yes" [](https://expedia.ca/Greenville-Hotels-Fairfield-Inn-By-Marriott-Greenville-Spartanburg-Airport.h67753.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Best Western Hotels in Aiken ](https://www.expedia.ca/Aiken-Hotels-Best-Western.0-0-d6058112--bBestWestern.Travel-Guide-Filter-Hotels) - 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