Title: Hotels by Independent in Upstate South Carolina from CA $79 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![I was surprised to see this waterfall in the middle of the city! #parks #nature #southcarolina #waterfall](https://images.trvl-media.com/place/1388/fb367afc-81f4-43d0-8f61-0b0f8e73a9aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by HTN ![](https://images.trvl-media.com/place/1388/fb367afc-81f4-43d0-8f61-0b0f8e73a9aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina Independent ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/91e6d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/6abd26aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/589bd84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1,005 reviews) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene CA $150 CA $187 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/01f08951.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/462068d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/34438b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) Clemson 8.2/10 Very good (1,005 reviews) "Love this hotel. It’s a little home away from home for me ❤️❤️❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacey [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/4bf90c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/cc74e7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (640 reviews) "The hotel was clean staff was amazing room was outstanding." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford CA $222 CA $291 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/a8a1fed9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/402009cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/834e3d3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exercise/lap pool](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/86c1e212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Inn and Suites [](https://www.expedia.ca/Greenville-Hotels-1314-S-Pleasantburg-Dr.h95668169.Hotel-Information) Greenville 6.2/10 (180 reviews) "Enjoyed my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyler [](https://www.expedia.ca/Greenville-Hotels-1314-S-Pleasantburg-Dr.h95668169.Hotel-Information) ![Golf](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/63d829f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/199642a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn [](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Clemson 9.6/10 Exceptional (965 reviews) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mindi CA $205 CA $228 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/020b11bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/ae3f38f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/71449a4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/4ea5cb8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Horizon Inn & Suites [](https://www.expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) Anderson 4.8/10 (250 reviews) "Think it's an nice place at an affordable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany CA $66 CA $79 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/8963c3c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (561 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan CA $195 CA $217 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/d217b18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/cb83efe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Patrick Square [](https://www.expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) Clemson 9.8/10 Exceptional (792 reviews) "Clean room, great location, wonderful staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joyce CA $205 CA $228 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/120000/116600/116562/48c989d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/120000/116600/116562/80c051e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/120000/116600/116562/a0150f81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/120000/116600/116562/8deac1ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Pelham Inn by IHG [](https://www.expedia.ca/Greenville-Hotels-Econo-Lodge-Suites-Greenville.h116562.Hotel-Information) Greenville 7.2/10 Good (893 reviews) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $76 CA $83 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Greenville-Hotels-Econo-Lodge-Suites-Greenville.h116562.Hotel-Information) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/61217476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/2d11b158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/cc01b08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/002ffe20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Greenville-Haywood Mall [](https://www.expedia.ca/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) Greenville 9.2/10 Wonderful (200 reviews) "Great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daecia CA $150 CA $165 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-07®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Independent.0-0-d6057939--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Independent.0-0-d6057939--bIndependent.Travel-Guide-Filter-Hotels) ## Top Upstate South Carolina Hotel Reviews ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Breakfast was fresh. Place was clean and had a nice stay. " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "The room was amazing, the amenities were top notch, I've just gotta find a reason to come back!" [](https://expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Hampton Inn & Suites Greenville-Downtown-RiverPlace](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989_y.jpg) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace 10/10 Excellent "On site covered parking, especially if it is valet" [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![AC Hotel By Marriott Greenville](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/575c54cb_y.jpg) ### AC Hotel By Marriott Greenville 10/10 Excellent "Super clean and very elegant room with balcony" [](https://expedia.ca/Greenville-Spartanburg-Hotels-AC-Hotel-By-Marriott-Greenville.h58282504.Hotel-Information) ![Hyatt Place Greenville Downtown](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "Extremely clean. We’re very accommodating to our pets. Friendly staff" [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88_y.jpg) ### The Westin Poinsett Greenville 10/10 Excellent "👍" [](https://expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Room was clean for the most part. The couch had some things on it, other than that, great check in, great bar and bartenders and amazing looking lobby." [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. 10/10 Excellent "Easy parking. Friendly and helpful staff. For me I found the value good for the cost that was paid. Breakfast was hot and fresh every morning. Bed was clean and comfort. I would stay here again. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Awesome hotel and very convenient for visiting Clemson." 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