Title: Book the Best Upstate South Carolina FAMILY FRIENDLY Hotels - Kid-Friendly Hotels in Upstate South Carolina, SC | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Family Hotels in Upstate South Carolina, SC ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Family Hotels Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-16&endDate=2025-10-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=FAMILY) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-17&endDate=2025-10-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=FAMILY) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=FAMILY) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=FAMILY) ## Top Upstate South Carolina Family Hotels ![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/3ccb6df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/d8b2892f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/f5139881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Gaffney by IHG Gaffney 8.6/10 Excellent (386) "Friendly helpful staff, room was clean. " CA $103 CA $113 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area Seneca 9.4/10 Exceptional (196) "Nice hotel by the lake" CA $181 CA $199 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/b54ae3f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ac0c08fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ca99d7c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville I-385 Inn & Suites Greenville 9.2/10 Wonderful (1376) "Clean room, super friendly staff, good breakfast. " CA $119 CA $131 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/1ebed4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/c05bf676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/573947b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Gaffney Gaffney 8.6/10 Excellent (642) "The staff (except on check in) were so very friendly. The room was very nice and clean. The bed was very comfortable. I would recommend this hotel. " CA $130 CA $142 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/389cca02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/64115ebf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/4c01aca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0c8d8851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG Anderson 9.0/10 Wonderful (570) "Good breakfast, clean " CA $145 CA $161 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/f59bfe6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/498d5401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/36a85341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/0007de95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Greenville Woodruff Road Greenville 9.2/10 Wonderful (1010) "Staff was very friendly, room was super clean and the location is perfect — convenient to EVERYTHING! Will definitely stay here again. " CA $156 CA $172 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/1999d91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/9b41a13e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking (1 King Bed)](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/5fb93bc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Haywood Greenville 7.4/10 Good (1090) "Good accomadation for the price." CA $97 CA $107 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/7f8f2b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/76bc86a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/f179f4b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area Clemson 8.2/10 Very good (1006) "Awesome place to stay" CA $131 CA $146 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/015cc42b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/3ff858d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/2bc62b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/5af30e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Greenville Mauldin Greenville 9.0/10 Wonderful (279) "Excellent stay " CA $159 CA $175 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-Courtyard-By-Marriott-Greenville-Mauldin.h58945857.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/b9f7d424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/0c07d0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/87260578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/c1f887b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Greenville Downtown Greenville Downtown 9.6/10 Exceptional (1012) "Great location, restaurants and shopping nearby. Hotel itself was also excellent. " CA $179 CA $197 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=6057939&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Excellent" [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "The staff were very friendly. I checked out and left my phone in the room and they allowed me to go back in the room, no hassle at all to retrieve my phone!!" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Room was very clean, hotel staff was very nice, overall great experience!! We will be back!!" [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Clean room, beautiful view!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Clean room" [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Clean rooms" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Stayed for a quick stop but everything was good " [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Hampton Inn & Suites Greenville Airport, SC](//images.trvl-media.com/lodging/12000000/11920000/11919200/11919192/de1bb5e2_y.jpg) ### Hampton Inn & Suites Greenville Airport, SC 10/10 Excellent "Clean room " [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Airport.h11919192.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](//images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Excellent service from the staff. They sent several text asking how are stay was going and if we needed anything. Had one small issue with the room’s thermostat but that was fixed in less than an hour of requesting the service." [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels with a Pool in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - [Hotels with Free Airport Shuttle in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Airport-Shuttle.0-0-d242-tHotelswithFreeAirportShuttle.Hotel-Filter-Destinations) - [Hotels with Free Breakfast in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Breakfast.0-0-d242-tHotelswithFreeBreakfast.Hotel-Filter-Destinations) - [Hotels with Free Parking in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Parking.0-0-d242-tHotelswithFreeParking.Hotel-Filter-Destinations) - [Hotels with Tennis Courts in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Tennis-Courts.0-0-d242-tHotelswithTennisCourts.Hotel-Filter-Destinations) - [Lgbt Friendly Hotels in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-LGBT-Friendly-Hotel.0-0-d242-tLGBTFriendlyHotel.Hotel-Filter-Destinations) - [Scuba Diving Hotels in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Scuba-Diving-Vacations.0-0-d242-tscubadivingvacations.Hotel-Filter-Destinations) - [Hotels near Donaldson Center](https://www.expedia.ca/Donaldson-Center-Airport-Hotels.0-aGDC-0.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Gantt](https://www.expedia.ca/Gantt-Hotels-Hotels-With-Smoking-Rooms.0-0-d553248634999376437-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Green Avenue](https://www.expedia.ca/Green-Avenue-Greenville-Hotels-LGBT-Friendly-Hotel.0-n553248635976476062-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels near Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Airport-Hotels.0-aGMU-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Boutique-Hotel.0-n6348006-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Cheap-Hotels.0-n6348006-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Historic-Hotel.0-n6348006-0-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Hotel-With-Pool.0-n6348006-0-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Hotels-With-Bar.0-n6348006-0-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Hotels-With-Free-Airport-Shuttle.0-n6348006-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Hotels-With-Free-Breakfast.0-n6348006-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Hotels-With-Hot-Tubs.0-n6348006-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Hotels-With-Indoor-Pool.0-n6348006-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Hotels-With-Kitchenettes.0-n6348006-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Luxury-Hotel.0-n6348006-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Oceanfront-Hotels.0-n6348006-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Pet-Friendly-Hotel.0-n6348006-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Romantic-Hotel.0-n6348006-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Shopping Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Shopping-Hotel.0-n6348006-0-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Spa-Hotel.0-n6348006-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Waterpark-Hotels.0-n6348006-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Hotels near Haywood Mall](https://www.expedia.ca/Haywood-Mall-Hotels.0-l6130785-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Cheap-Hotels.0-0-d183944-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Luxury-Hotel.0-0-d183944-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Pet-Friendly-Hotel.0-0-d183944-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Spa-Hotel.0-0-d183944-tSpaHotel.Travel-Guide-Filter-Hotels) - [Mauldin Hotels](https://www.expedia.ca/Mauldin-Hotels.d183944.Travel-Guide-Hotels) - [Hotels near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Hotels.0-l553248635941390934-0.Travel-Guide-Filter-Hotels) - [Hotels near Shriners Hospitals for Children Greenville](https://www.expedia.ca/Shriners-Hospitals-For-Children-Greenville-Hotels.0-l704436698448793600-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Boutique-Hotel.0-0-d6239-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Cheap-Hotels.0-0-d6239-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Golf-Hotel.0-0-d6239-tGolfHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Luxury-Hotel.0-0-d6239-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Pet-Friendly-Hotel.0-0-d6239-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Spa-Hotel.0-0-d6239-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Wedding-Hotels.0-0-d6239-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Flights from Donaldson Center](https://www.expedia.ca/lp/airports/gdc/flights-from-donaldson-center-airport) - [Flights from Greenville Downtown](https://www.expedia.ca/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Mauldin](https://www.expedia.ca/lp/flights/183944/flights-from-mauldin) - [Flights from Anderson (AND) to Greenville (GDC)](https://www.expedia.ca/lp/flights/and/gdc/anderson-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.ca/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Asheville (AVL) to Greenville (GDC)](https://www.expedia.ca/lp/flights/avl/gdc/asheville-to-greenville) - [Flights from Birmingham (BHM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/bhm/gmu/birmingham-to-greenville) - [Flights from Burlington (BTV) to Greenville (GDC)](https://www.expedia.ca/lp/flights/btv/gdc/burlington-to-greenville) - [Flights from Clemson (CEU) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ceu/gdc/clemson-to-greenville) - [Flights from Danville (DAN) to Greenville (GDC)](https://www.expedia.ca/lp/flights/dan/gdc/danville-to-greenville) - [Flights from Washington (DCA) to Greenville (GDC)](https://www.expedia.ca/lp/flights/dca/gdc/washington-to-greenville) - [Flights from Denver (DEN) to Greenville (GDC)](https://www.expedia.ca/lp/flights/den/gdc/denver-to-greenville) - [Flights from Des Moines (DSM) to Greenville (GDC)](https://www.expedia.ca/lp/flights/dsm/gdc/des-moines-to-greenville) - [Flights from Detroit (DTW) to Greenville (GDC)](https://www.expedia.ca/lp/flights/dtw/gdc/detroit-to-greenville) - [Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ewr/gdc/newark-liberty-intl-airport-to-greenville) - [Flights from Rome (FCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/fco/gdc/rome-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/gkt/gdc/gatlinburg-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GMU)](https://www.expedia.ca/lp/flights/gkt/gmu/gatlinburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/grd/gdc/greenwood-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.ca/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.ca/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from New York (JFK) to Greenville (GDC)](https://www.expedia.ca/lp/flights/jfk/gdc/new-york-to-greenville) - [Flights from New York (JFK) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jfk/gmu/new-york-to-greenville) - [Flights from Las Vegas (LAS) to Greenville (GDC)](https://www.expedia.ca/lp/flights/las/gdc/las-vegas-to-greenville) - [Flights from Pickens (LQK) to Greenville (GDC)](https://www.expedia.ca/lp/flights/lqk/gdc/pickens-to-greenville) - [Flights from Orlando (MCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/mco/gdc/orlando-to-greenville) - [Flights from Manteo (MEO) to Greenville (GMU)](https://www.expedia.ca/lp/flights/meo/gmu/manteo-to-greenville) - [Flights from Miami (MIA) to Greenville (GDC)](https://www.expedia.ca/lp/flights/mia/gdc/miami-to-greenville) - [Flights from Miami (MIA) to Greenville (GMU)](https://www.expedia.ca/lp/flights/mia/gmu/miami-to-greenville) - [Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.ca/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Chicago (ORD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ord/gdc/chicago-to-greenville) - [Flights from Norfolk (ORF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/orf/gmu/norfolk-to-greenville) - [Flights from West Palm Beach (PBI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/pbi/gmu/west-palm-beach-to-greenville) - [Flights from Philadelphia (PHL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/phl/gmu/philadelphia-to-greenville) - [Flights from Raleigh (RDU) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rdu/gmu/raleigh-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from San Antonio (SAT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/sat/gdc/san-antonio-to-greenville) - [Flights from Savannah (SAV) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sav/gmu/savannah-to-greenville) - [Flights from Schenectady (SCH) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sch/gmu/schenectady-to-greenville) - [Flights from Louisville (SDF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sdf/gmu/louisville-to-greenville) - [Flights from Sanford (SFM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sfm/gmu/sanford-to-greenville) - [Flights from Newburgh (SWF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/swf/gmu/newburgh-to-greenville) - [Flights from Montreal (YUL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yul/gmu/montreal-to-greenville) - [Flights from Vancouver (YVR) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yvr/gmu/vancouver-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GDC)](https://www.expedia.ca/lp/flights/yyz/gdc/toronto-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yyz/gmu/toronto-to-greenville) - [7th Inning Splash Waterpark](https://www.expedia.ca/7th-Inning-Splash-Waterpark-Piedmont.d553248621532656702.Vacation-Attraction) - [Central Vacations](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides) - [Discovery Island Water Park](https://www.expedia.ca/Discovery-Island-Water-Park-Greenville.d553248621532656705.Vacation-Attraction) - [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Mauldin Vacations](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides) - [Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction) - [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide) - [Book Family Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Family-Hotel.0-0-d6057939-tFamilyHotel.Travel-Guide-Filter-Hotels)