Title: Book the Best BUSINESS Hotels in Upstate South Carolina in 2025 | Expedia.ca

 

[Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides)

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# Find Business Hotels in Upstate South Carolina, SC

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## Check availability on Upstate South Carolina Business Hotels

Tonight

[Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Top Upstate South Carolina Business Hotels

![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/3ccb6df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/d8b2892f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/f5139881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Gaffney by IHG

Gaffney

8.6/10

Excellent

(400)

"Great place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timothy

CA $110

CA $120 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/cbe6a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e408dd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Abernathy of Clemson

Clemson

9.6/10

Exceptional

(550)

"Very friendly staff, great location, great room and very clean! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jenny

CA $175

CA $195 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/347fe1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/270-2efd6ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/3c50d204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Seneca Clemson Area US-123

Downtown

8.0/10

Very good

(654)

"Ok hotel for a quick stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lori

CA $112

CA $132 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/8238721d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/96a62179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Greenville Golf Resort & Conference Center

Greenville

8.8/10

Excellent

(1020)

"The hotel and staff were very nice. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

CA $129

CA $142 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

![Two queen beds nonsmoking](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/65554714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/361c6cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free breakfast](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/c7944b9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/c13da5b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Easley

Easley

9.4/10

Exceptional

(665)

"Always a pleasure to stay here at the Hampton Inn in Easley. Clean rooms, a quiet location and friendly staff too. Added bonus of a decent breakfast too."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

John

CA $177

CA $197 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Easley-Hotels-Hampton-Inn-Easley.h1453465.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/f179f4b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/ca80b104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/76bc86a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Clemson - University Area

Clemson

8.2/10

Very good

(1004)

"Great stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Linda

CA $131

CA $145 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ac0c08fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ca99d7c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/b54ae3f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Greenville I-385 Inn & Suites

Greenville

9.2/10

Wonderful

(1382)

"Loved my stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Himani

CA $118

CA $129 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

![BBQ/picnic area](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/704d2b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/8e2d308e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/b8a8a3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites by Hilton Greenville Downtown

Greenville Downtown

9.6/10

Exceptional

(1005)

"Great property overall. Very convenient location to restaurants and shopping"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $171

CA $193 total

includes taxes & fees

Nov 25 - Nov 26

[](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information)

![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/a9307e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

9.4/10

Exceptional

(200)

"Beautiful clean hotel. Staff was very welcoming. Breakfast area was very clean with many options. The river view is so beautiful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Linda

CA $168

CA $185 total

includes taxes & fees

Nov 26 - Nov 27

[](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/01b325b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/5e9a8e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/7c5ccfc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft Greenville Downtown

Greenville Downtown

9.0/10

Wonderful

(1004)

"Perfect place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie

CA $176

CA $194 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&regionId=6057939&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Upstate South Carolina Hotel Reviews

![Hyatt Place Greenville/Haywood](//images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg)

### Hyatt Place Greenville/Haywood

10/10 Excellent

"Room was beautiful! Food was great ! "

[](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information)

![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg)

### Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent

"For very spacious and nice"

[](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg)

### Hilton Greenville

10/10 Excellent

"Comfy room as always "

[](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information)

![Quality Inn Seneca Clemson Area US-123](//images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg)

### Quality Inn Seneca Clemson Area US-123

10/10 Excellent

"Everything has been very good with staff, the room and the property. Would ask that on the days there is no housekeeping service that the trash and fresh towels would be addressed. "

[](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg)

### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

10/10 Excellent

"EVERYTHING was great. The staff, the amenities, the room. Even the location was very favorable"

[](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg)

### La Quinta Inn & Suites by Wyndham Greenville Haywood

10/10 Excellent

"Room was great"

[](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information)

![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg)

### Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent

"The room was large, clean, and the staff was friendly. The room rates are very reasonable."

[](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

![Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd](//images.trvl-media.com/lodging/1000000/210000/202200/202137/b07dd898_y.jpg)

### Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent

"Knowledgeable and friendly staff. Walking distance to nearby eateries. Clean room."

[](https://expedia.ca/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h202137.Hotel-Information)

![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg)

### Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent

"Clean room "

[](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

## Frequently asked questions

### How much do business-friendly hotels in Upstate South Carolina cost?

> You can expect to pay between and per night for business-friendly hotels in Upstate South Carolina. Terrific deals on stays that are suitable for work-related travellers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

### What are the best business-friendly hotels in Upstate South Carolina?

> That depends on your destination in Upstate South Carolina. Lots of business travellers to Greenville choose [Homewood Suites by Hilton Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information). This 3-stars property has a barbecue grill and a swimming pool. [SpringHill Suites by Marriott Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) is another excellent option if you're arranging a meeting or working remotely in Greenville. A swimming pool and a barbecue grill are some of the useful amenities at this 2.5-stars retreat. You can choose from multiple business-friendly hotels in Upstate South Carolina that have a total average guest review rating of .

### How many business-friendly hotels are there in Upstate South Carolina?

> When your next meeting or conference takes you someplace in Upstate South Carolina, you'll have business-friendly hotels to choose from.

### What are the best cheap business-friendly hotels in Upstate South Carolina?

> That depends on which corner of Upstate South Carolina work is taking you. If you're headed to Greenville, [SpringHill Suites by Marriott Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) combines affordability with business-friendly amenities. A terrace and a barbecue grill are a couple of its many conveniences. On your way to Spartanburg? Look up [Tru by Hilton Spartanburg](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information). WiFi and a playground help make this cheaper property a favourite with corporate visitors. Business-friendly hotels start at just per night, so your next work trip doesn't have to stretch your finances. There are loads of fun and free things to do wherever you're headed in Upstate South Carolina. If business is taking you to Greenville, try to find time to swing by [Greenville County Museum of Art](https://www.expedia.ca/Greenville-County-Museum-Of-Art-Greenville-Downtown.d6082717.Vacation-Attraction). You can also go sightseeing without spending a dime in Spartanburg. [Spartanburg Regional Hospital](https://www.expedia.ca/Spartanburg-Regional-Hospital-Spartanburg.d6245689.Vacation-Attraction) is one of the most popular free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

### What are the top business-friendly motels in Upstate South Carolina?

> Expedia's business-friendly motels in Upstate South Carolina come with amenities that are the ideal mix of work and play. One of our best options is [Urban Boutique Hotel, BW Signature Collection](https://www.expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) in Greenville. Located around 3 kilometres northeast of the downtown area, WiFi and front desk services are the start of its many conveniences. Another stay that appeals to corporate travellers is [Days Inn by Wyndham Greenville](https://www.expedia.ca/Greenville-Hotels-Days-Inn-By-Wyndham-Greenville.h22276.Hotel-Information). It's approximately 8 kilometres east of the centre of Greenville and features a swimming pool, front desk services and more.There are a ton of things to keep you entertained when you're not hard at work in Greenville. [The Peace Centre](https://www.expedia.ca/The-Peace-Center-Greenville-Downtown.d6082705.Vacation-Attraction) and [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) should be on your sightseeing checklist.

### Are there any family-friendly hotels in Upstate South Carolina that are also business friendly?

> You'll discover some terrific family-friendly hotels that are also business friendly in Upstate South Carolina. If you're on your way to Greenville, take a look at [SpringHill Suites by Marriott Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information). It comes with useful amenities like complimentary breakfast and WiFi and has a 2.5-stars rating. Another option to consider is [Hampton Inn & Suites Greenville-Downtown-RiverPlace](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information). This 2.5-stars stay in Greenville is perfect for both leisure and business travellers and offers complimentary breakfast, room service and more. Greenville offers loads of family-friendly attractions when you're ready to discover the sights. [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) and [Greenville Zoo](https://www.expedia.ca/Greenville-Zoo-Greenville-Downtown.d6082709.Vacation-Attraction) will keep your crew entertained.

### Are there any 5-star business-friendly hotels in Upstate South Carolina?

> In Upstate South Carolina, 5-star business-friendly hotels are difficult to come by. However, there are some 4-star properties that cater to corporate travellers. If you're making tracks to Greenville for work, base yourself at [The Westin Poinsett Greenville](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information). It comes with handy amenities including pillow top mattresses and room service. Or, put your laptop down and feet up at [Greenville Marriott](https://www.expedia.ca/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information), also in Greenville. Take advantage of its conveniences including a swimming pool and pillow top mattresses.

### Why book your business-friendly hotel in Upstate South Carolina with Expedia?

> We're here to help you find a suitable business-friendly hotel when work takes you on the road. From free parking and WiFi to gyms and on-site restaurants, our properties have the things you'll need to get the job done.

### How can I find cheap business-friendly hotels in Upstate South Carolina?

> When work takes you to Upstate South Carolina, our "business friendly" filter will help you find the right hotel. From WiFi to workspaces and meeting rooms, they come with the amenities you need for a productive and comfortable stay. You can also narrow your search by your preferred star rating and budget to see the most affordable properties.

### What is there to do in Upstate South Carolina near my business-friendly hotel?

> The most important travel accessory for your Upstate South Carolina business journey is a good itinerary for your free time! [The Peace Centre](https://www.expedia.ca/The-Peace-Center-Greenville-Downtown.d6082705.Vacation-Attraction), [Greenville Zoo](https://www.expedia.ca/Greenville-Zoo-Greenville-Downtown.d6082709.Vacation-Attraction) and [The Children's Museum of the Upstate](https://www.expedia.ca/The-Childrens-Museum-Of-The-Upstate-Greenville-Downtown.d553248621532656777.Vacation-Attraction) are some of the well-known sights if you're staying in Greenville. Spartanburg also has plenty of superb attractions, such as [Spartanburg Memorial Auditorium](https://www.expedia.ca/Spartanburg-Memorial-Auditorium-Spartanburg.d6245714.Vacation-Attraction), [Spartanburg Regional History Museum](https://www.expedia.ca/Spartanburg-Regional-History-Museum-Spartanburg.d553248621532656805.Vacation-Attraction) and [Chapman Cultural Centre](https://www.expedia.ca/Chapman-Cultural-Center-Spartanburg.d6278987.Vacation-Attraction).

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-   [7th Inning Splash Waterpark](https://www.expedia.ca/7th-Inning-Splash-Waterpark-Piedmont.d553248621532656702.Vacation-Attraction)
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-   [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction)

-   [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide)

-   [Book Business Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Business-Hotel.0-0-d6057939-tBusinessHotel.Travel-Guide-Filter-Hotels)