Title: Hotels by Best Western in Upstate South Carolina from CA $111 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Best Western in Upstate South Carolina from CA $111 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Best Western Hotels ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/4bfc6efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/2fe691fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/800/708/c6283d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Greenville Airport Inn Greenville 7.8/10 Good (1024) "Clean room, great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miguel CA $101 CA $111 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/d02ac737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking (with Sofabed)](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/6c096589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/b1fdad7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/e845fce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Spartanburg Northwest Spartanburg 8.2/10 Very good (802) "It was a good stay for the area near mall and stores " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $118 CA $131 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/fd542db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/a7c81686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/9b9d3bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/0689cad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Travelers Rest Greenville Travelers Rest 7.6/10 Good (1001) "The staff was cheerful and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judy CA $136 CA $149 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/83901eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson Seneca 8.4/10 Very good (626) "Convenient for Clemson visits." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen CA $125 CA $138 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Best-Western.0-0-d6057939--bBestWestern.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Best-Western.0-0-d6057939--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Upstate South Carolina Hotel Reviews ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Room was great" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "The room was large, clean, and the staff was friendly. The room rates are very reasonable." [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "I don’t eat breakfast " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](//images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg) ### ECHO Suites Extended Stay by Wyndham Spartanburg 10/10 Excellent "Everything went smoothly and convenient to restaurants " [](https://expedia.ca/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Clean room " [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Motel 6 Greenville, SC](//images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/af5363f6_y.jpg) ### Motel 6 Greenville, SC 10/10 Excellent "Many different restaurants to choose from. Very clean and great service." [](https://expedia.ca/Greenville-Hotels-Motel-6-Greenville.h1107497.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Very nice stay here. Very clean and friendly staff! Didn't try breakfast. Too expensive. " [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Comfort Inn Greenville - Haywood Mall](//images.trvl-media.com/lodging/1000000/30000/25000/24994/6e5638cc_y.jpg) ### Comfort Inn Greenville - Haywood Mall 10/10 Excellent "Breakfast was very good. Several selections. Only items with room to mention are, one. The TV comes on at Max volume with no way to prevent it in any settings. The volume switch on remote will lower the sound, but it takes a long time to reduce the volume. Apologies to anyone in an adjoining room. Secondly, the hair dryer was wonky. The switch on the dryer did not work (broken). The only way to use was to press the reset button on the plug to get it to come on (at high temp, no low temp available). And to turn it off, press the circuit breaker switch on the plug. Other than that, the facility, the room and overall stay was very good. " [](https://expedia.ca/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Great hotel!" 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[Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.ca/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Chicago (ORD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ord/gdc/chicago-to-greenville) - [Flights from Norfolk (ORF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/orf/gmu/norfolk-to-greenville) - [Flights from West Palm Beach (PBI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/pbi/gmu/west-palm-beach-to-greenville) - [Flights from Philadelphia (PHL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/phl/gmu/philadelphia-to-greenville) - [Flights from Portland (PWM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/pwm/gmu/portland-to-greenville) - [Flights from Raleigh (RDU) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rdu/gmu/raleigh-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from San Antonio (SAT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/sat/gdc/san-antonio-to-greenville) - [Flights from Savannah (SAV) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sav/gmu/savannah-to-greenville) - [Flights from Schenectady (SCH) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sch/gmu/schenectady-to-greenville) - [Flights from Louisville (SDF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sdf/gmu/louisville-to-greenville) - [Flights from Sanford (SFM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sfm/gmu/sanford-to-greenville) - [Flights from Newburgh (SWF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/swf/gmu/newburgh-to-greenville) - [Flights from Montreal (YUL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yul/gmu/montreal-to-greenville) - [Flights from Vancouver (YVR) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yvr/gmu/vancouver-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GDC)](https://www.expedia.ca/lp/flights/yyz/gdc/toronto-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yyz/gmu/toronto-to-greenville) - [7th Inning Splash Waterpark](https://www.expedia.ca/7th-Inning-Splash-Waterpark-Piedmont.d553248621532656702.Vacation-Attraction) - [Central Vacations](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides) - [Discovery Island Water Park](https://www.expedia.ca/Discovery-Island-Water-Park-Greenville.d553248621532656705.Vacation-Attraction) - [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Mauldin Vacations](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides) - [Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction) - [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide) - [Book Best Western in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Best-Western.0-0-d6057939--bBestWestern.Travel-Guide-Filter-Hotels)