Photo by Bill Eaker

Muscatine Vacation Rentals

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Vacation Rentals in Muscatine

Captain's Cove is a county getaway with private ponds for all of life's moments!

9.6 out of 10, Exceptional, (26)
"Neat little cabin with plenty of space. We were all able to sleep in our own beds while we were in the are for Christmas. The fish tank was a hit with my kiddos."
Captain's Cove is a county getaway with private ponds for all of life's moments!

La Casita Guest House

10.0 out of 10, Exceptional, (13)
"We were in town for a family reunion and our stay was so enjoyable. "
La Casita Guest House

Beautiful 3 bedroom uniquely designed home for small to large families! Pets ok!

8.0 out of 10, Very good, (5)
"Definitely an older home, but such a fun decorating scheme and updated insides. Great stay :)"
The price is CA $218
CA $543 total
includes taxes & fees
Aug 4 - Aug 5
Beautiful 3 bedroom uniquely designed home for small to large families! Pets ok!

Lucy’s House Single Family Bungalow

9.6 out of 10, Exceptional, (63)
"Clean and comfortable. "
The price is CA $151
CA $178 total
includes taxes & fees
Jul 27 - Jul 28
Lucy’s House Single Family Bungalow

Minutes from anywhere

10.0 out of 10, Exceptional, (113)
"I’ve stayed here a few times now, it’s very comfortable and I’ll be booking more stays."
The price is CA $67
CA $116 total
includes taxes & fees
Aug 11 - Aug 12
Minutes from anywhere

The Historic Castle Cicali

The price is CA $329
CA $896 total
includes taxes & fees
Aug 18 - Aug 19
The Historic Castle Cicali

The Barn Loft

9.6 out of 10, Exceptional, (5)
"Great property and would most definitely stay again!!!"
The price is CA $321
CA $581 total
includes taxes & fees
Jul 29 - Jul 30
The Barn Loft

Charming 1920s, pet friendly home, centrally located!

9.2 out of 10, Wonderful, (23)
"Charming older home great when traveling with a pet. Host was very accommodating and responsive. "
The price is CA $122
CA $260 total
includes taxes & fees
Jul 27 - Jul 28
Charming 1920s, pet friendly home, centrally located!

Quiet neighborhood surrounded by parks near multipurpose trail through QC

10.0 out of 10, Exceptional, (30)
"Great place to stay with a dog while visiting family in the quad cities. Convenient location, nice yard, very clean place! "
Quiet neighborhood surrounded by parks near multipurpose trail through QC

The Nelson Lofts - Unit 6 (1 BR)

10.0 out of 10, Exceptional, (6)
"I was in town for My daughter’s dance competition so it was just her and I and this place was PERFECT!! We will be back!!"
The price is CA $119
CA $303 total
includes taxes & fees
Aug 3 - Aug 4
The Nelson Lofts - Unit 6 (1 BR)

3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!

10.0 out of 10, Exceptional, (26)
"Our stay was very nice! Everything we needed and easy to find!! Would definitely recommend this home!"
The price is CA $136
CA $344 total
includes taxes & fees
Jul 27 - Jul 28
3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!

Lewis M. Fisher House

The price is CA $287
CA $737 total
includes taxes & fees
Jul 29 - Jul 30
Lewis M. Fisher House

Renwick Mansion Guest House

9.6 out of 10, Exceptional, (81)
"Our stay was great! The owners were very friendly and helpful. The house is beautiful and inviting. It is in a great location for things to do. We would definitely stay here again!"
Renwick Mansion Guest House

Experience a 3 bedroom historic apartment Rock Island, IL

10.0 out of 10, Exceptional, (1)
"The apartment was wonderful, a step back in time! The beds were comfortable and the apartment was so charming. The gardens were so pretty, we enjoyed the peace and quiet of the area. Definitely would stay again! "
The price is CA $273
CA $538 total
includes taxes & fees
Jul 29 - Jul 30
Experience a 3 bedroom historic apartment Rock Island, IL

Bettendorf Gem: 2BR Condo w/ King Bed & Garage

2.0 star property
9.8 out of 10, Exceptional, (10)
"Great condo in a very nice neighborhood. We enjoyed our time here close to everything we wanted to do. Condo was very clean and had everything we needed. Would 100% book again when we come back to the area! "
Bettendorf Gem: 2BR Condo w/ King Bed & Garage

Luxurious Condo family-friendly Closer to attractions! Eatery,Walmart&lot more!

The price is CA $246
CA $453 total
includes taxes & fees
Jul 29 - Jul 30
Luxurious Condo family-friendly Closer to attractions! Eatery,Walmart&lot more!

Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex

10.0 out of 10, Exceptional, (28)
"We really enjoyed the house. Good for relaxing."
The price is CA $136
CA $344 total
includes taxes & fees
Jul 27 - Jul 28
Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex

East Village Victorian Gem with River Views; walk to dining & shopping

10.0 out of 10, Exceptional, (3)
"Such a beautiful home in a great location! We had everything we needed there and had a fantastic time."
The price is CA $381
CA $598 total
includes taxes & fees
Jul 28 - Jul 29
East Village Victorian Gem with River Views; walk to dining & shopping

Near TBK Bank Sports Complex: Quad Cities Townhome

3.0 star property
Near TBK Bank Sports Complex: Quad Cities Townhome

Scenic 1 Bedroom

9.6 out of 10, Exceptional, (57)
"Great place to stay"
Scenic 1 Bedroom
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Muscatine Hotel Reviews

Frequently asked questions

Can I find a vacation rental in Muscatine?

Yes, we offer vacation rentals in Muscatine close to Muscatine Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Muscatine is known for its riverfront and baseball games. Make sure you have time to check out the theaters and entertainment choices during your trip.

What are some of the best vacation home rentals that Muscatine has to offer?

Beautiful 3 bedroom uniquely designed home for small to large families! Pets ok!: Visitors like this Muscatine vacation home rental. It is equipped with an arcade game room, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a stovetop, and a microwave.

How many vacation rentals are there in Muscatine?

With 4 Expedia vacation rentals, you're sure to find just the right place for your Muscatine stay.

What’s there to see and do in Muscatine?

Mississippi River and Riverside Park are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Muscatine Aquatic Center. While here, Cedar River and Muscatine Art Center are other places worth a visit.

What’s a vacation rental in Muscatine like?

A vacation rental is a private property where you can stay for short or long periods in Muscatine. Vacation rentals offer extras like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for families.