Title: 10 Best Hotels in Murex Lakes, Sanibel for 2026 | Expedia.ca [Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Murex Lakes Car Rentals](https://expedia.ca/Car-Rentals-In-Murex-Lakes.d553248635976468770.Car-Rental-Guide)[Murex Lakes Vacations](https://expedia.ca/Murex-Lakes.d553248635976468770.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Murex Lakes, Sanibel - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 21 - Dec 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-12-21&endDate=2025-12-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Where to stay in Murex Lakes Find the best Murex Lakes areas and neighborhoods for the activities you enjoy most. - West End - Mid Island - East End - Beachview Country Club Estates - Sanctuary ![Fort Myers showing a sandy beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31797-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography ![Fort Myers which includes signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31796-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography ![Fort Myers showing island views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31793-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography ![Fort Myers which includes a pebble beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31789-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/427000/427051-Sanibel-Captiva-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=977664051587067904) ![West End map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:egs%60DlmrtNyjAco%40Xei%40tyAkvB_%40evB%7EfCyvG%7ExAqa%40jfC%7BAyAzo%40mFpn%40o%7D%40ncDg_%40nw%40euAn%7DAyoA%7CsCagBftA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=rYtfIojIXwdhtd9RgwR7P6VGoPQ=) ### West End While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach. [See properties](https://www.expedia.ca/Hotel-Search?regionId=977664051587067904) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496800-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496794-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496797-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496795-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496033-southwest-coast-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=977663677668896768) ![Mid Island map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ivk%60Dfj%7EsNoU%7Bk%40sk%40m%5EsTlS_%5DeYmi%40%7B%5CiBiQvJ%7BUd%5B%7Be%40zP_e%40fTgRbLkPpq%40lLdi%40MnQEdb%40b%7E%40%7EWzn%40hZphArFzb%40b%40h%5DefC%60B&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=VxGJcF1rdvQCDBU5UqL_Xs8Jsy8=) ### Mid Island While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach. [See properties](https://www.expedia.ca/Hotel-Search?regionId=977663677668896768) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/495000/495910-south-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496810-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496815-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496813-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496031-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=977663465835589632) ![East End map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wkl%60DbmvsNsq%40kLxBsM%7EBFpByDtDqR%7D%40_DNoZaBqNm%40aNViE%7D%40uKyFcOVqExFeGpE%60A%7CDpDlFpN%7EYjj%40nOt_%40zc%40%60aAk%7B%40X&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hlweUqTn_teHrd_l720zC5CKvf4=) ### East End While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse. [See properties](https://www.expedia.ca/Hotel-Search?regionId=977663465835589632) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496031-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496033-southwest-coast-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496099-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496100-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496067-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976658737) ![Beachview Country Club Estates map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_xi%60DnhzsN%7DF%7BKm%40qJo%60%40WcFgQsIGkFm%5BlPuInCdJrU%3Fh%40cBhAh%40vCwAve%40%7CjAuVF&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=01bhKNjFz-Z_Q0nxmzzaWzGMm0I=) ### Beachview Country Club Estates If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976658737) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976469368) ![Sanctuary map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Dct%60DjfqtNcl%40iNz%40%7D%5Ef%5DeBxrAodAbBcLfV%7DAbCzGkT%60OqDlf%40wIpR%7BHnXyHlIcf%40fByCzK&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=poR-ON5_hQI0xWhU_gQlcmdLxUw=) ### Sanctuary While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368) ## Top Murex Lakes Hotel Reviews ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Always a good stay " [](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Matanzas Inn Bayside Resort and Marina](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/fc463bf9_y.jpg) ### Matanzas Inn Bayside Resort and Marina 10/10 Excellent "We had another great stay at Matanzas Inn! The “cottage” is across the street and up a stairwell into a great studio apartment with a king bed that had a full size fridge, cooktop with 4 burners, microwave, cookware and a dishwasher. Very comfortable accommodation! The real bonus is being able to walk around and enjoy all the restaurants & bars with live music everywhere. Penny is a great lady and we look forward to our next stay here!" [](https://expedia.ca/Fort-Myers-Hotels-Matanzas-Inn-Bayside-Resort-And-Marina.h2665085.Hotel-Information) ![Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/8158a459_y.jpg) ### Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway 10/10 Excellent "Wonderful breakfast selection. Worth the price for the close proximity to Fort Meyer beach. " [](https://expedia.ca/Fort-Myers-Beach-Hotels-Hampton-Inn-Suites-Fort-Myers-BeachSanibel-Gateway.h551886.Hotel-Information) ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "Clean perfectly located, friendly staff, updated room with an awesome view. Great food on the premises. The only thing we didnt like was the additional charge for parking. " [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Allure Suites](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55_y.jpg) ### Allure Suites 10/10 Excellent "Allure Suites Offers a Home Away From Home! Suites are stocked and very clean!!! Staff is excellent!!! Love This Place!! Glenda Fortune " [](https://expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Doubletree by Hilton Fort Myers at Bell Tower Shops](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c_y.jpg) ### Doubletree by Hilton Fort Myers at Bell Tower Shops 10/10 Excellent "Courteous, friendly staff. Clean room. Nice Hotel." [](https://expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Pink Shell was amazing. The room was awesome. The beach and pool were great. The food was wonderful. All in all this resort was perfect for our anniversary and we will definitely be back. " [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![The Westin Cape Coral Resort At Marina Village](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e_y.jpg) ### The Westin Cape Coral Resort At Marina Village 10/10 Excellent "The staff was great! My granddaughter felt like a princess there. From the outside parking attendant to all the rest we came in contact with. I would highly recommend the Westin in Cape Coral. Jonelle " [](https://expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Hyatt Vacation Club at Coconut Cove, Bonita Springs](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/fedffc57_y.jpg) ### Hyatt Vacation Club at Coconut Cove, Bonita Springs 10/10 Excellent "Staff was very welcoming & rooms were clean and comfortable. Very quiet. " [](https://expedia.ca/Bonita-Springs-Hotels-Hyatt-Vacation-Club-At-Coconut-Cove.h991114.Hotel-Information) ## Frequently asked questions ### What's it like in Murex Lakes? ### How many hotels are there in Murex Lakes? ### If I need to cancel my hotel reservation in Murex Lakes, will I receive a refund? ### What is there to do around this Sanibel neighborhood? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [3 Star Hotels in Sanibel Captiva Island ](https://www.expedia.ca/3Star-Sanibel-Captiva-Island-Hotels.s30-0-d6326115.Travel-Guide-Filter-Hotels) - [Hotels near Bailey - Matthews Shell Museum ](https://www.expedia.ca/Bailey-Matthews-Shell-Museum-Hotels.0-l6123901-0.Travel-Guide-Filter-Hotels) - [Hotels near Bowman's Beach ](https://www.expedia.ca/Bowmans-Beach-Hotels.0-l6296151-0.Travel-Guide-Filter-Hotels) - [Bright Water Hotels ](https://www.expedia.ca/Bright-Water-Sanibel-Hotels.0-n553248635976473851-0.Travel-Guide-Filter-Hotels) - [Hotels near Captiva Beach ](https://www.expedia.ca/Captiva-Beach-Hotels.0-l6296288-0.Travel-Guide-Filter-Hotels) - [Captiva Hotels ](https://www.expedia.ca/Captiva-Hotels.d86452.Travel-Guide-Hotels) - [Hotels near Causeway Islands Park A ](https://www.expedia.ca/Causeway-Islands-Park-A-Hotels.0-l6298744-0.Travel-Guide-Filter-Hotels) - [Hotels near Causeway Islands Park B ](https://www.expedia.ca/Causeway-Islands-Park-B-Hotels.0-l6298750-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Chateaux Sur Mer ](https://www.expedia.ca/Chateaux-Sur-Mer-Sanibel-Hotels-Casino-Hotel.0-n553248635976472800-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Chateaux Sur Mer Hotels ](https://www.expedia.ca/Chateaux-Sur-Mer-Sanibel-Hotels.0-n553248635976472800-0.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Gulf Pines ](https://www.expedia.ca/Gulf-Pines-Sanibel-Hotels-Oceanfront-Hotels.0-n553248635976472804-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Adults-Only-Resorts.0-n553248635976479667-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Hotels-With-A-Lazy-River.0-n553248635976479667-0-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Hotels-With-Indoor-Pool.0-n553248635976479667-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Gulf Shores ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels-Pet-Friendly-Hotel.0-n553248635976479667-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Gulf Shores Hotels ](https://www.expedia.ca/Gulf-Shores-Sanibel-Hotels.0-n553248635976479667-0.Travel-Guide-Filter-Hotels) - [Gumbo Limbo Hotels ](https://www.expedia.ca/Gumbo-Limbo-Sanibel-Hotels.0-n553248635976480905-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Island Woods ](https://www.expedia.ca/Island-Woods-Sanibel-Hotels-Cheap-Hotels.0-n553248635976477725-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels near J. 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