Title: Book the Best Central Missouri LUXURY Hotels - Upscale Hotels in Central Missouri, MO | Expedia.ca [Central Missouri Travel Guide](https://expedia.ca/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.ca/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Vacation Rentals in Central Missouri](https://expedia.ca/Central-Missouri-Vacation-Rentals.d6058776.Travel-Guide-VacationRentals)[Flights to Central Missouri](https://expedia.ca/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.ca/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Missouri.d6058776.Car-Rental-Guide)[Central Missouri Vacation Packages](https://expedia.ca/Central-Missouri.d6058776.Destination-Travel-Guides) ![Missouri State Capitol which includes an administrative building, heritage architecture and a fountain](https://images.trvl-media.com/place/6092643/f7036169-7e6d-403b-b3a3-fac711433497.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Central Missouri, MO - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Luxury Hotels Tonight [Nov 30 - Dec 1](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-11-30&endDate=2025-12-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 1 - Dec 2](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-12-01&endDate=2025-12-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-12-12&endDate=2025-12-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Central Missouri Luxury Hotels ![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/77d8da33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/0abef2e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/e7ee761d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/8a965f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Columbia Columbia 7.4/10 Good (1014) "Clean, good breakfast, good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jetse CA $82 CA $93 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/4cb82576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/d57fed98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/d2b3af17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/ae9109fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### voco The Tiger Hotel Columbia, MO by IHG Columbia 8.8/10 Excellent (1005) "Clean room! Easy parking! Love the Tiger!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah CA $172 CA $216 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.4/10 Good (1075) "Wonderful place with lots to do" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina CA $97 CA $138 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite (Two Double Beds) | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/1773a780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/b09c0391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1003) "Awesome staff, great food and service!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $125 CA $186 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/1e51ead0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/8ad6955b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/5302832b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/8bf18cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel Sedalia Downtown Historic District 9.2/10 Wonderful (572) "Our room was beautiful and spotless, the front desk personnel were friendly and knowledgeable about the history of the hotel, the wait staff at the restaurant were efficient and friendly. Our experience here was wonderful and we look forward to our next visit." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Toleah CA $144 CA $163 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/350205ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/abe0b627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/c053648f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/a72704ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Laci's Country Inn Knob Noster 7.0/10 Good (159) "Nice stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rodney CA $85 CA $101 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Clinton-Hotels-Lacis-Country-Inn.h7768577.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/805c2520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/fd258818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/c428cb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn Columbia 8.8/10 Excellent (1209) "Stayed here several times and was very happy with our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reynaldo CA $101 CA $114 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/52bc64ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/0665f04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/a99e46d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/3db07fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Columbia Clark Lane Columbia 6.6/10 (1012) "Great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dwight CA $68 CA $77 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Columbia-Clark-Lane.h459668.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/312544dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/c159a6d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/fc5d9ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/cd10e4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Boonville Boonville 6.4/10 (651) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley CA $87 CA $98 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-Boonville.h40165.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/5f892660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/57b8a773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/c69d8b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks Osage Beach 7.2/10 Good (1007) "the rooms are clean but the hotel is old . the breakfast is just ok nothing special ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $86 CA $93 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-14&endDate=2025-12-15®ionId=6058776&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_6058776) ## Top Central Missouri Hotel Reviews ![Greenlight Inn & Suites](https://images.trvl-media.com/lodging/1000000/20000/18300/18239/ad4ef74b_y.jpg) ### Greenlight Inn & Suites 10/10 Excellent "Close to free way. " [](https://expedia.ca/Rolla-Hotels-Greenstay-Hotel-Suites.h18239.Hotel-Information) ![Baymont by Wyndham Columbia, MO](https://images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "Good" [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Best Western Plus Columbia Inn](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "Room was clean and the staff were helpful and everyone courteous. The gentleman taking care of breakfast was especially nice!" [](https://expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Stoney Creek Hotel Columbia](https://images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "It was decent " [](https://expedia.ca/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Ramada by Wyndham Columbia](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/77d8da33_y.jpg) ### Ramada by Wyndham Columbia 10/10 Excellent "Me and my wife had a wonderful time" [](https://expedia.ca/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Great Stay" [](https://expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Days Inn by Wyndham Rolla](https://images.trvl-media.com/lodging/1000000/50000/40300/40279/1759c9c5_y.jpg) ### Days Inn by Wyndham Rolla 10/10 Excellent "Yes great " [](https://expedia.ca/Rolla-Hotels-Days-Inn-By-Wyndham-Rolla.h40279.Hotel-Information) ![Baymont by Wyndham Rolla](https://images.trvl-media.com/lodging/2000000/1060000/1054200/1054131/ddf62a40_y.jpg) ### Baymont by Wyndham Rolla 10/10 Excellent "Great people " [](https://expedia.ca/Rolla-Hotels-Baymont-By-Wyndham-Rolla.h1054131.Hotel-Information) ![Capitol Plaza Hotel Jefferson City](https://images.trvl-media.com/lodging/1000000/10000/400/369/ad47cfa0_y.jpg) ### Capitol Plaza Hotel Jefferson City 10/10 Excellent "Breakfast was terrible. Room was very clean. Staff was impeccable. Parking was safe and free. Old hotel, but very clean. Beds were comfortable. 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