Title: Book the Best BUSINESS Hotels in Central Missouri in 2026 | Expedia.ca [Central Missouri Travel Guide](https://expedia.ca/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.ca/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Vacation Rentals in Central Missouri](https://expedia.ca/Central-Missouri-Vacation-Rentals.d6058776.Travel-Guide-VacationRentals)[Flights to Central Missouri](https://expedia.ca/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.ca/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Central-Missouri.d6058776.Car-Rental-Guide)[Central Missouri Vacation Packages](https://expedia.ca/Central-Missouri.d6058776.Destination-Travel-Guides) ![Missouri State Capitol which includes an administrative building, heritage architecture and a fountain](https://images.trvl-media.com/place/6092643/f7036169-7e6d-403b-b3a3-fac711433497.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Central Missouri, MO from CA $82 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Business Hotels Tonight [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 29 - Dec 30](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2025-12-29&endDate=2025-12-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6058776&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Central Missouri business-friendly hotels ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/12000000/11800000/11795200/11795146/8028d7d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11800000/11795200/11795146/afd23e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/12000000/11800000/11795200/11795146/47528afd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11800000/11795200/11795146/86b81b96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Harrisonville [](https://www.expedia.ca/Clinton-Hotels-Knights-Inn-Harrisonville.h11795146.Hotel-Information) Harrisonville 7.8/10 Good (248) "Nice little place, just not big enough for a family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Greg CA $86 CA $98 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Clinton-Hotels-Knights-Inn-Harrisonville.h11795146.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/11000000/10270000/10269500/10269458/w557h421x37y0-fe178932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10270000/10269500/10269458/3ee2ee65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/11000000/10270000/10269500/10269458/2ab8291a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/11000000/10270000/10269500/10269458/9959bb10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn Motel [](https://www.expedia.ca/Rolla-Hotels-Country-Inn-Motel.h10269458.Hotel-Information) Licking 7.2/10 Good (332) "Friendly staff and clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peggy CA $75 CA $82 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Rolla-Hotels-Country-Inn-Motel.h10269458.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/850000/848900/848802/3d8da06d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/850000/848900/848802/10b09bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848900/848802/0b485be7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/850000/848900/848802/773e9f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Cuba [](https://www.expedia.ca/Rolla-Hotels-Days-Inn-Suites-By-Wyndham-Cuba.h848802.Hotel-Information) Cuba 7.4/10 Good (762) "Perfect for travelers... ez on/off the highway. Comfortable bed. Big parking lot. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $103 CA $117 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Rolla-Hotels-Days-Inn-Suites-By-Wyndham-Cuba.h848802.Hotel-Information) ![In-room safe, desk, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/e99f99fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/943aa2e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![ATM/banking on site](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/fd5803b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/b608d22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Cuba [](https://www.expedia.ca/Rolla-Hotels-Super-8-By-Wyndham-Cuba.h861493.Hotel-Information) Cuba 8.8/10 Excellent (990) "Clean room, nice staff and relaxing atmosphere " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $113 CA $128 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Rolla-Hotels-Super-8-By-Wyndham-Cuba.h861493.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/4000000/3020000/3016300/3016208/0609c73e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, deep soaking tub, free toiletries, hair dryer](https://images.trvl-media.com/lodging/4000000/3020000/3016300/3016208/4df50c9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/4000000/3020000/3016300/3016208/975c0d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/4000000/3020000/3016300/3016208/f3adbe6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn St. Robert [](https://www.expedia.ca/Rolla-Hotels-Americas-Best-Value-Inn-St-Robert.h3016208.Hotel-Information) St. Robert 8.4/10 Very good (726) "Nice spot for the price. Rooms were clean, and the staff was super friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Phillip CA $104 CA $117 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Rolla-Hotels-Americas-Best-Value-Inn-St-Robert.h3016208.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/2000000/1060000/1054200/1054131/ddf62a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1060000/1054200/1054131/1aa6993d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Multiple Beds, Hot Tub, Pool View](https://images.trvl-media.com/lodging/2000000/1060000/1054200/1054131/e0c0a0db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1060000/1054200/1054131/c2b81b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Rolla [](https://www.expedia.ca/Rolla-Hotels-Baymont-By-Wyndham-Rolla.h1054131.Hotel-Information) Rolla 8.0/10 Very good (1002) "Love the lake in the back! Rooms are clean, parking is easy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keith CA $110 CA $123 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Rolla-Hotels-Baymont-By-Wyndham-Rolla.h1054131.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/892800/892739/a8d56f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/1000000/900000/892800/892739/71693432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/900000/892800/892739/fc148036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/900000/892800/892739/53465cf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn St. Robert-Fort Leonard Wood [](https://www.expedia.ca/Rolla-Hotels-Sleep-Inn-St-Robert-Fort-Leonard-Wood.h892739.Hotel-Information) St. Robert 8.8/10 Excellent (775) "Staff was great and hotel very nuce" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) judd CA $89 CA $103 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Rolla-Hotels-Sleep-Inn-St-Robert-Fort-Leonard-Wood.h892739.Hotel-Information) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/28000000/27600000/27597500/27597474/9054d766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/28000000/27600000/27597500/27597474/2a40c055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/28000000/27600000/27597500/27597474/22d3a49c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/28000000/27600000/27597500/27597474/a12a75d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakes Inn [](https://www.expedia.ca/Clinton-Hotels-Lakes-Inn.h27597474.Hotel-Information) Warsaw 8.0/10 Very good (354) "It was a great stay. Better than I could have imagined. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $109 CA $123 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Clinton-Hotels-Lakes-Inn.h27597474.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12300/12289/01a9b1bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12300/12289/c59a5d1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom sink](https://images.trvl-media.com/lodging/1000000/20000/12300/12289/e60bcf90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12300/12289/a31b7784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harrisonville Inn & Suites [](https://www.expedia.ca/Clinton-Hotels-Harrisonville-Inn-Suites.h12289.Hotel-Information) Harrisonville 8.2/10 Very good (498) "Room clean, nice bed and couch, friendly staff and quiet!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelly CA $85 CA $93 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Clinton-Hotels-Harrisonville-Inn-Suites.h12289.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/4000000/4000000/3992100/3992017/27255c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/4000000/4000000/3992100/3992017/9248be46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/4000000/4000000/3992100/3992017/50cc19d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/4000000/4000000/3992100/3992017/6d64a5da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hawthorn Extended Stay by Wyndham Saint Robert [](https://www.expedia.ca/Rolla-Hotels-Hawthorn-Suites-By-Wyndham-St-Robert.h3992017.Hotel-Information) St. Robert 7.8/10 Good (1000) "Easy parking" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon CA $92 CA $104 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Rolla-Hotels-Hawthorn-Suites-By-Wyndham-St-Robert.h3992017.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-11&endDate=2026-01-12®ionId=6058776&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ![Country Inn & Suites by Radisson, Columbia, MO](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Great and friendly check in" [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Wyndham Executive Center Columbia](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/86998653_y.jpg) ### Wyndham Executive Center Columbia 10/10 Excellent "Everything was clean and the staff was very on top of it! " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Executive-Center-Columbia-Mall.h22359.Hotel-Information) ![Baymont by Wyndham Columbia, MO](https://images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "We had a great stay at this place. We tend to drive between Denver and St. Louis area often, and it’s nice to have this place on our list of approved places. You can tell they really care about providing a nice place to stay." [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Stoney Creek Hotel Columbia](https://images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "Everything was as expected. " [](https://expedia.ca/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Quality Inn St. Robert - Ft. Leonard Wood](https://images.trvl-media.com/lodging/1000000/220000/218400/218324/63ed2b69_y.jpg) ### Quality Inn St. Robert - Ft. Leonard Wood 10/10 Excellent "Very nice room." [](https://expedia.ca/Rolla-Hotels-Quality-Inn-St-Robert-Ft-Leonard-Wood.h218324.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Loved the warm pool! The Santa workshop treat was amazing! " [](https://expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Camden on the Lake Resort & Spa](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b_y.jpg) ### Camden on the Lake Resort & Spa 10/10 Excellent "It was fancy. " [](https://expedia.ca/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Wingate by Wyndham - Columbia](https://images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6_y.jpg) ### Wingate by Wyndham - Columbia 10/10 Excellent "Friendly staff. Large room and clean " [](https://expedia.ca/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Drury Inn & Suites Columbia Stadium Boulevard](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/3e728377_y.jpg) ### Drury Inn & Suites Columbia Stadium Boulevard 10/10 Excellent "Such a great orient" [](https://expedia.ca/Columbia-Hotels-Drury-Inn-Suites-Columbia-Stadium-Boulevard.h42129.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Central Missouri cost? ### What are the best business-friendly hotels in Central Missouri? ### How many business-friendly hotels are there in Central Missouri? ### What are the best cheap business-friendly hotels in Central Missouri? ### Are there any family-friendly hotels in Central Missouri that are also business friendly? ### Are there any 5-star business-friendly hotels in Central Missouri? ### Why book your business-friendly hotel in Central Missouri with Expedia? ### How can I find cheap business-friendly hotels in Central Missouri? ### What is there to do in Central Missouri near my business-friendly hotel? ## Explore a world of travel with Expedia - 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