Title: Book the Best BOUTIQUE Hotels in Mission District in 2026 | Expedia.ca [Mission District Travel Guide](https://expedia.ca/San-Francisco-Mission-District.dx134035)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Mission District Car Rentals](https://expedia.ca/Car-Rentals-In-Mission-District.d134035.Car-Rental-Guide)[Mission District Vacations](https://expedia.ca/Mission-District.d134035.Destination-Travel-Guides) ![Mission District which includes outdoor art](https://images.trvl-media.com/place/134035/1fb7195b-23e3-4a0f-a5ef-22b484069f64.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/134035/1fb7195b-23e3-4a0f-a5ef-22b484069f64.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mission District Boutique Hotels Tonight [Jan 26 - Jan 27](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2026-01-26&endDate=2026-01-27&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 27 - Jan 28](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2026-01-27&endDate=2026-01-28&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2026-01-30&endDate=2026-02-01&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=134035&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mission District boutique hotels ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/5bd0b8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/7814d514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/78023bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/cb9fb20d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Berkeley City Club [](https://www.expedia.ca/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) Telegraph District 8.8/10 Excellent (699 reviews) "Wonderful, beautiful, old world hotel, right in the heart of bustling Berkeley. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter CA $327 CA $376 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/173b8dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/a3393d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/4817709a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/19abbe84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zephyr San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) Fisherman's Wharf 8.6/10 Excellent (2,400 reviews) "The balcony view was amazing and parking was perfect. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ena M CA $172 CA $259 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/0fdb0ab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/a452632b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/95039663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/2c399818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Triton [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Triton.h1110.Hotel-Information) Union Square 8.8/10 Excellent (1,004 reviews) "We had a great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy CA $114 CA $194 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Triton.h1110.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/79b46bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/a6855f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/b513dbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/3d698b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Palihotel-San-Francisco.h49777.Hotel-Information) Union Square 8.4/10 Very good (645 reviews) "Great staff, fun and warm atmosphere" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $123 CA $179 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/San-Francisco-Hotels-Palihotel-San-Francisco.h49777.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/e1f91bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/2d47f36f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/7158d83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/f0a07fbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Argonaut Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) Fisherman's Wharf 9.4/10 Exceptional (1,234 reviews) "Ok hotel in a good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catia CA $276 CA $383 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) ![Suite (Skyline Waterfront Penthouse) | View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/1b7910ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/400/384/df9b3b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/631bdce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/1000000/10000/400/384/a04417ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor Court Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1,004 reviews) "Beautifully remodeled, convenient, great staff. Room was nicely furnished and comfortable bed. Would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Analea CA $199 CA $297 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/100ffc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/e282d47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/da0bd574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clancy, Autograph Collection by Marriott [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1,007 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey CA $246 CA $346 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/a6ba3784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/2711ab7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/105e4279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/b8c723b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marker Union Square San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) Union Square 9.0/10 Wonderful (1,182 reviews) "Great staff, great vibe, beautiful hotel, lovely room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nanette CA $202 CA $238 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/700/660/27f19182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/700/660/87dba6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/700/660/7ebf7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/700/660/f20db6f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Emblem San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Emblem-San-Francisco.h660.Hotel-Information) Union Square 9.4/10 Exceptional (1,010 reviews) "We enjoyed our stay, close to cable cars shopping dining bars " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) HALEY CA $198 CA $288 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Emblem-San-Francisco.h660.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/876/bf356ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/900/876/eb66d5c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, hypo-allergenic bedding, down comforters](https://images.trvl-media.com/lodging/1000000/10000/900/876/ec2f51ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/876/e25769c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Warwick San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Warwick-San-Francisco.h876.Hotel-Information) Union Square 8.2/10 Very good (1,004 reviews) "Room was great and clean, amazing ambiance. Staff was always able to answer any questions. Both the restaurant and the bar were alright. A little noisy from outside noises, but otherwise a great place for a good price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cody CA $140 CA $214 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/San-Francisco-Hotels-Warwick-San-Francisco.h876.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-10&endDate=2026-02-11®ionId=134035&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Mission District Hotel Reviews ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Everything was fantastic from check-in the beauty of the hotel the cleanliness the ease of parking friendlyness of the staff the room was made up perfectly truly enjoyed the great breakfast five stars. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "The customer service and room were spectacular! This might be my go-to when traveling to SF. " [](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Taj Campton Place](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d044cc49_y.jpg) ### Taj Campton Place 10/10 Excellent "Yes. Almost as soon as we called to replace a burnt out lightbulb, someone was there to change it. " [](https://expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) ![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "Great stay" [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "The staff was wonderful. The room was very clean and spacious. Loved the charm!" [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Bay Landing San Francisco Airport Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1110800/1110785/0c231d9b_y.jpg) ### Bay Landing San Francisco Airport Hotel 10/10 Excellent "Very convenient, comfortable, and a good price." [](https://expedia.ca/San-Francisco-Hotels-Bay-Landing-San-Francisco-Airport-Hotel.h1110785.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "The best location in San Francisco and very clean hotel. Love it!!!" [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![Hilton San Francisco Union Square](https://images.trvl-media.com/lodging/1000000/30000/25700/25622/e6c58ddf_y.jpg) ### Hilton San Francisco Union Square 10/10 Excellent "good" [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Union-Square.h25622.Hotel-Information) ![Hotel Zephyr San Francisco](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fd976170_y.jpg) ### Hotel Zephyr San Francisco 10/10 Excellent "Great location! Friendly Staff and fun hotel😎" [](https://expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ## Frequently asked questions ### What's there to see and do in Mission District? ### What's the best way to get to my boutique hotel in Mission District? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Cheap Hotels in Bernal Heights ](https://www.expedia.ca/Bernal-Heights-San-Francisco-Hotels-Cheap-Hotels.0-n553248621561136356-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Bernal Heights ](https://www.expedia.ca/Bernal-Heights-San-Francisco-Hotels-Couples-Resorts-Hotels.0-n553248621561136356-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Bernal Heights ](https://www.expedia.ca/Bernal-Heights-San-Francisco-Hotels-Family-Hotel.0-n553248621561136356-0-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Bernal Heights ](https://www.expedia.ca/Bernal-Heights-San-Francisco-Hotels-Historic-Hotel.0-n553248621561136356-0-tHistoricHotel.Travel-Guide-Filter-Hotels) - 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[Hotels with Waterslides in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Hotels-With-Waterslides.0-n800128-0-tHotelswithWaterslides.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-LGBT-Friendly-Hotel.0-n800128-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Lake Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Lake-Hotels.0-n800128-0-tLakeHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Luxury-Hotel.0-n800128-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Mountain-Hotels.0-n800128-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Romantic-Hotel.0-n800128-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - 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