Title: Book the Best South Carolina Midlands SPA Resorts - Spa Hotels in South Carolina Midlands, SC | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/184000/184006-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in South Carolina Midlands, SC ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Midlands Spa Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-30&endDate=2025-10-31&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-31&endDate=2025-11-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Carolina Midlands Spa Hotels ![Body treatments, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/30000/20100/20030/d90e1b28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20100/20030/64598b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/20100/20030/f4cdc91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/20100/20030/4c3cb9cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Willcox Aiken 9.6/10 Exceptional (141) "Wonderful stay all around." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anastasija CA $400 CA $448 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Aiken-Hotels-The-Willcox.h20030.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/f6280554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/4be28b9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/6db04cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Columbia, SC Columbia 7.8/10 Good (1032) "The staff is friendly, breakfast is great and the rooms are comfy and clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $100 CA $112 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/713c2524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/7d63bca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/5b020e41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Florence, Tapestry Collection by Hilton Florence 8.8/10 Excellent (592) "Room was very clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LeLandra CA $182 CA $204 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/800000/798500/798446/317b0952.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage, 4 Bedrooms, Balcony](https://images.trvl-media.com/lodging/1000000/800000/798500/798446/9a165410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 indoor pools, seasonal outdoor pool, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/800000/798500/798446/96f40d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798446/24906fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ballantyne, A Luxury Collection Hotel, Charlotte Ballantyne 9.4/10 Exceptional (1003) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wudeneh CA $314 CA $362 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Charlotte-Hotels-The-Ballantyne.h798446.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/8063695a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/b49fc2c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Bedrooms (The Lady Anne Room)](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/a490469b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/764f9317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Morgan and Wells B&B Shelby 9.6/10 Exceptional (89) "Melanie, the owner and Ronnie, the chef were wonderful hosts!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SUSAN CA $224 CA $252 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Shelby-Hotels-Morgan-And-Wells-BB.h11043190.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/40000000/39750000/39744300/39744243/048a40b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39750000/39744300/39744243/a9c7be2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/40000000/39750000/39744300/39744243/5733136b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/40000000/39750000/39744300/39744243/3cd9c127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Charlotte, Autograph Collection Uptown Charlotte 9.2/10 Wonderful (706) "Very clean property and the staff were all attentive and friendly! Wonderful stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darrin CA $244 CA $281 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Charlotte-Hotels-Grand-Bohemian-Hotel-Charlotte.h39744243.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/60000000/59180000/59177800/59177778/330a283a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, pool views, open daily](https://images.trvl-media.com/lodging/60000000/59180000/59177800/59177778/f7a3dd22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LED TV, iPod dock, first-run movies](https://images.trvl-media.com/lodging/60000000/59180000/59177800/59177778/2c583301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/60000000/59180000/59177800/59177778/9d2a3a84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Charlotte Uptown Charlotte 9.4/10 Exceptional (925) "Gorgeous hotel, friendly staff, great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexandria CA $331 CA $416 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Charlotte-Hotels-JW-Marriott-Charlotte.h59177778.Hotel-Information) ![Sauna, hot tub, body treatments, body wraps, body scrubs, detox wraps](https://images.trvl-media.com/lodging/3000000/2910000/2903600/2903551/w4000h2662x0y0-9e57f6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2910000/2903600/2903551/00325e37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/3000000/2910000/2903600/2903551/8364de98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, body treatments, body wraps, body scrubs, detox wraps](https://images.trvl-media.com/lodging/3000000/2910000/2903600/2903551/482e5269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, Charlotte Uptown Charlotte 9.0/10 Wonderful (284) "We had a wonderful time. Our room was absolutely beautiful.!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benita CA $835 CA $963 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Charlotte-Hotels-The-Ritz-Carlton.h2903551.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=6057938&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top South Carolina Midlands Hotel Reviews ![Graduate by Hilton Columbia SC](//images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Great staff" [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, SC](//images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9_y.jpg) ### Country Inn & Suites by Radisson, Columbia, SC 10/10 Excellent "It is an older hotel but for the price it was great and it was very convenient to what we needed to do. Thank you very much." [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Allen University](https://www.expedia.ca/Allen-University-Hotels.0-l6245638-0.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Guest-Houses.d553248634998974994-aaGuestHouses.Travel-Guide-Accommodation) - [Arcadia Lakes Hotels](https://www.expedia.ca/Arcadia-Lakes-Hotels.d553248634998974994.Travel-Guide-Hotels) - [Inns in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Inns.d553248634998974994-aaInns.Travel-Guide-Accommodation) - [Hotels near Benedict College](https://www.expedia.ca/Benedict-College-Hotels.0-l553248635056398076-0.Travel-Guide-Filter-Hotels) - [Apartments in Blythewood](https://www.expedia.ca/Blythewood-Apartments.d180657-aaApartments.Travel-Guide-Accommodation) - 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