Title: Book the Best South Carolina Midlands FAMILY FRIENDLY Hotels from CA $104 - Kid-Friendly Hotels in South Carolina Midlands, SC | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Family Hotels in South Carolina Midlands, SC from CA $104 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Midlands Family Hotels Tonight [Jan 8 - Jan 9](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-01-08&endDate=2026-01-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Tomorrow [Jan 9 - Jan 10](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) ## Our top choices for South Carolina Midlands family-friendly hotels ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/67341601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1002) "Clean spacious room, nice amenities and good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $167 CA $186 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/69d65d2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/70afa25a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/0baee182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/737d93ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Pointe Rock Hill Near University [](https://www.expedia.ca/Rock-Hill-Hotels-Clarion-Pointe-Rock-Hill-Near-Training-Camp.h22006.Hotel-Information) Rock Hill 8.8/10 Excellent (1046) "Stay was good area felt safe, would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean CA $93 CA $104 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Rock-Hill-Hotels-Clarion-Pointe-Rock-Hill-Near-Training-Camp.h22006.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/33d87b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/470d616b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/2db4f7f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) Columbia 7.6/10 Good (999) "Very Clean and newly renovated. Decent breakfast and helpful staff." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Elizabeth CA $93 CA $104 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/ebea43b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/b5687a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) Florence 8.6/10 Excellent (2527) "Clean rooms, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suman CA $97 CA $109 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/d2e2f4b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/6255d302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/8b9ec04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) Columbia 8.8/10 Excellent (1816) "Was a good location for us, and the staff were friendly.... " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Reginald CA $121 CA $135 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/290000/280900/280847/bf42c10b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/290000/280900/280847/fb8052a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/290000/280900/280847/1066846a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/290000/280900/280847/7b8f742f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Ft. Jackson Maingate [](https://www.expedia.ca/Columbia-Hotels-Comfort-Inn-Suites-Ft-Jackson-Maingate.h280847.Hotel-Information) Columbia 7.4/10 Good (708) "Great experience. Would stay again in the future " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trish CA $113 CA $127 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Columbia-Hotels-Comfort-Inn-Suites-Ft-Jackson-Maingate.h280847.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/94a4d77a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) Florence 9.0/10 Wonderful (835) "My go to stay while in Fairfax. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $135 CA $151 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/9f136d0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/7f29240e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/ca93dcba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/824b9567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence [](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Florence 8.0/10 Very good (1694) "Staff was great, breakfast was well stocked " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) constance CA $129 CA $145 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Children's play area - outdoor](https://images.trvl-media.com/lodging/54000000/53350000/53349300/53349276/af39b97e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/54000000/53350000/53349300/53349276/02dee216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/54000000/53350000/53349300/53349276/b92c38c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53349300/53349276/2096bb16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Fort Mill, SC [](https://www.expedia.ca/Rock-Hill-Hotels-Tru-By-Hilton-Fort-Mill.h53349276.Hotel-Information) Fort Mill 9.0/10 Wonderful (575) "Nice staff, clean room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelby CA $123 CA $137 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Rock-Hill-Hotels-Tru-By-Hilton-Fort-Mill.h53349276.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/68fe8568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/d546b726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/319d53d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/355b44a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Columbia/Harbison [](https://www.expedia.ca/Columbia-Hotels-Hyatt-Place-ColumbiaHarbison.h327027.Hotel-Information) Irmo 8.0/10 Very good (1002) " Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $111 CA $124 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/Columbia-Hotels-Hyatt-Place-ColumbiaHarbison.h327027.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-22&endDate=2026-01-23®ionId=6057938&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top South Carolina Midlands Hotel Reviews ![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "This hotel was exceptional! Very clean whirlpool tub was nice and having all the amenities needed in the room was great ! I would definitely stay here again " [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Clarion Pointe Rock Hill Near University](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/69d65d2e_y.jpg) ### Clarion Pointe Rock Hill Near University 10/10 Excellent "Lobby was clean (although smelled strongly of air freshener). Rooms were clean and spacious. Price was very reasonable, as was pet fee (only $20!). Definitely recommend!" [](https://expedia.ca/Rock-Hill-Hotels-Clarion-Pointe-Rock-Hill-Near-Training-Camp.h22006.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg) ### Hampton Inn & Suites Florence Center 10/10 Excellent "Room was spotless! Bathroom was very clean as well. " [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Courtyard by Marriott Columbia Downtown at USC](https://images.trvl-media.com/lodging/1000000/10000/2300/2289/w3996h2667x0y0-8dd1e3e0_y.jpg) ### Courtyard by Marriott Columbia Downtown at USC 10/10 Excellent "Left early didn’t take breakfast " [](https://expedia.ca/Columbia-Hotels-Courtyard-By-Marriott-Columbia-Downtown-At-USC.h2289.Hotel-Information) ![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson 10/10 Excellent "Room was clean, staff was friendly " [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "As always great place " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Hyatt Place Columbia/Downtown/The Vista](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690567/c2bace01_y.jpg) ### Hyatt Place Columbia/Downtown/The Vista 10/10 Excellent " Room was great. Breakfast was okay" [](https://expedia.ca/Columbia-Hotels-Hyatt-Place-ColumbiaDowntownThe-Vista.h8690567.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Clean rooms, good breakfast " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Loved our stay ." 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