Title: Book the Best HISTORIC Hotels in Mesopotamia in 2025 | Expedia.ca

  

[Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides)

![Mesopotamia which includes forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196542-Mesopotamia.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Historic Hotels in Mesopotamia

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## Check availability on Mesopotamia Historic Hotels

Tonight

[Oct 4 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-04&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Mesopotamia Historic Hotels

![Casino](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/a75881f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/da57c485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/d7ac2335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/21b37ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Amérian Hotel Casino Gala

Resistencia

9.0/10

Wonderful

(163)

"Great service and attention!. I highly recommend this hotel . "

CA $90

CA $90 total

Oct 5 - Oct 6

[](https://www.expedia.ca/Resistencia-Hotels-Amerian-Hotel-Casino-Gala.h1197026.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-18&endDate=2025-10-19&regionId=6208836&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true)

## Top Mesopotamia Hotel Reviews

![Holiday Inn Express Rosario by IHG](//images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg)

### Holiday Inn Express Rosario by IHG

10/10 Excellent

"Very clean and spacious. Hearty breakfast. Very courteous staff"

[](https://expedia.ca/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information)

![Esplendor by Wyndham Savoy Rosario](//images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51_y.jpg)

### Esplendor by Wyndham Savoy Rosario

10/10 Excellent

"Excellent hotel Everything very comfortable, and convenient"

[](https://expedia.ca/Rosario-Hotels-Esplendor-By-Wyndham-Savoy-Rosario.h2803473.Hotel-Information)

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