Title: Book the Best Mesopotamia LUXURY Hotels - Upscale Hotels in Mesopotamia | Expedia.ca

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![Iguazu Falls featuring a cascade](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Mesopotamia Luxury Hotels

Tonight

[Jan 25 - Jan 26](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-01-25&endDate=2026-01-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Jan 26 - Jan 27](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-01-26&endDate=2026-01-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-01-30&endDate=2026-02-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

In two weeks

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Mesopotamia luxury hotels

![Suite, Terrace](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/3fe012c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, lunch served](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/fa3aedbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/d9f65657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's activities](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/11bcbc9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

[](https://www.expedia.ca/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information)

Foz do Iguaçu

9.8/10

Exceptional

(1,003 reviews)

"Perfect location and very attentive service, espacios and comfortable rooms "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Oslay

CA $1,059

CA $1,225 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information)

![Indoor pool, 3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/3de28959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/83cafc92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/7f654841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Iguazu Grand Resort Spa & Casino

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information)

Puerto Iguazú

9.0/10

Wonderful

(606 reviews)

"Big rooms Friendly and respectful staff Loved our stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amin

CA $423

CA $432 total

Jan 27 - Jan 28

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information)

![Private pool](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/c43a985d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/3d04f2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/1551ab16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/596c9ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gran Melia Iguazú

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information)

Puerto Iguazú

9.2/10

Wonderful

(1,011 reviews)

"From ther moment of arrival to the one leaving all staff and amenities were incredible."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alberto

CA $1,206

CA $1,214 total

Jan 28 - Jan 29

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information)

![2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/71380e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/5c71d910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Bathroom](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/d0267182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/d73ef262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Loi Suites Iguazú Hotel

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Loi-Suites-Iguazu-Hotel.h2450070.Hotel-Information)

Puerto Iguazú

9.2/10

Wonderful

(1,003 reviews)

"The room was spotless. The pools were amazing and the staff was friendly."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kathryn

CA $438

CA $446 total

Feb 9 - Feb 10

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Loi-Suites-Iguazu-Hotel.h2450070.Hotel-Information)

![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/82a469cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room (Earth) | View from room](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/7d6ce6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Bathroom](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/3ac32bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/cf5dfc79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Reserva Virgin Lodge

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-La-Cantera-Lodge-De-Selva-By-DON.h3020960.Hotel-Information)

Puerto Iguazú

8.4/10

Very good

(810 reviews)

"The hotel is in great shape in the middle of the jungle, the staff was very helpful. We booked their new years dinner, it was great food! We really enjoyed our stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ivan

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-La-Cantera-Lodge-De-Selva-By-DON.h3020960.Hotel-Information)

![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/260f31f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/71461004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/a8f544ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/7644a18e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Saint George

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Hotel-Saint-George.h3281425.Hotel-Information)

Puerto Iguazú

8.8/10

Excellent

(1,004 reviews)

"Good sized and clean room, wonderful staff, great location and beautiful swimming pool!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Maria

CA $160

CA $165 total

Jan 31 - Feb 1

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Hotel-Saint-George.h3281425.Hotel-Information)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/6394d862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/21b8d40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/3e2fe331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/f8a901a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Panoramic Grand

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Panoramic-Grand.h1829043.Hotel-Information)

Puerto Iguazú

8.8/10

Excellent

(636 reviews)

"Friendly staff great breakfast amazing views, location near town "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stefania

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Panoramic-Grand.h1829043.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/ab97ae19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/b6cde1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Triple Room](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/f17b57e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/544e495f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marcopolo Suites Iguazu

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Marcopolo-Suites-Iguazu.h4041467.Hotel-Information)

Puerto Iguazú

6.6/10

(324 reviews)

"Clean, and close to the center of the city."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rodolfo

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Marcopolo-Suites-Iguazu.h4041467.Hotel-Information)

![Outdoor pool, open 9 AM to 7 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/ca10ddeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dinner served, Argentinean cuisine, pool views ](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/5d6cd34f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor spa tub](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/714d6028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/678479c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique Hotel Delafonte

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Boutique-Hotel-De-La-Fonte.h3469387.Hotel-Information)

Puerto Iguazú

8.6/10

Excellent

(364 reviews)

"Great location, good restaurant, nice pools, very responsive staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-Boutique-Hotel-De-La-Fonte.h3469387.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/7e00f6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/90e69f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/787572d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/024260d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Aldea de la Selva Lodge

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-La-Aldea-De-La-Selva-Lodge.h3234974.Hotel-Information)

Puerto Iguazú

8.8/10

Excellent

(524 reviews)

"Authentic jungle stay with well maintained facilities and beautiful scenery. Rooms are ample and in great working condition. Best price-quality ratio in the area!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maximo

CA $166

CA $169 total

Jan 27 - Jan 28

[](https://www.expedia.ca/Puerto-Iguazu-Hotels-La-Aldea-De-La-Selva-Lodge.h3234974.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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