Title: Book The Best Hotels in Mesadha for 2026 from CA $127 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Mesadha](https://expedia.ca/Mesadha-Vacation-Rentals.d3000756489.Travel-Guide-VacationRentals)[Mesadha Car Rentals](https://expedia.ca/Car-Rentals-In-Mesadha.d3000756489.Car-Rental-Guide)[Mesadha Vacation Packages](https://expedia.ca/Mesadha.d3000756489.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 6 - Apr 7](https://www.expedia.ca/Hotel-Search?regionId=3000756489&startDate=2026-04-06&endDate=2026-04-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 7 - Apr 8](https://www.expedia.ca/Hotel-Search?regionId=3000756489&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=3000756489&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=3000756489&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesadha hotels ![Front of property](https://images.trvl-media.com/lodging/30000000/29970000/29967000/29966958/eee2df24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub](https://images.trvl-media.com/lodging/30000000/29970000/29967000/29966958/6c29a0bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29970000/29967000/29966958/afa5d163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/30000000/29970000/29967000/29966958/1ca82bb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Agnatio Hotel Spa [](https://www.expedia.ca/Sintiki-Hotels-Agnatio-Hotel-Spa.h29966958.Hotel-Information) Sintiki 9.8/10 Exceptional (9 reviews) "Nous avons passé un très agréable séjour. Le personnel a été d'une très grande gentillesse avec nous et tout s'est bien passé." ![France](https://a.travel-assets.com/egds/marks/flags/fr.svg) serge CA $107 CA $138 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Sintiki-Hotels-Agnatio-Hotel-Spa.h29966958.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/74000000/73250000/73245700/73245692/f7982f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/74000000/73250000/73245700/73245692/0c3fb207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/74000000/73250000/73245700/73245692/2f2aeecb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/74000000/73250000/73245700/73245692/8aa0012b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Philippos Xenia Hotel [](https://www.expedia.ca/Serres-Hotels-PHILIPPOS-XENIA-HOTEL.h73245692.Hotel-Information) Serres 8.4/10 Very good (27 reviews) "Comfortable, good location. The corridors and the rooms could use some renovation. The breakfast was adequate but uninspiring" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ANASTASSIOS CA $132 CA $166 total includes taxes & fees Apr 11 - Apr 12 [](https://www.expedia.ca/Serres-Hotels-PHILIPPOS-XENIA-HOTEL.h73245692.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/14000000/13240000/13234900/13234890/bd524f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/14000000/13240000/13234900/13234890/1a63c571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/14000000/13240000/13234900/13234890/b19e42d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room](https://images.trvl-media.com/lodging/14000000/13240000/13234900/13234890/4c61ef1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Acropol [](https://www.expedia.ca/Serres-Hotels-Acropol.h13234890.Hotel-Information) Serres 8.4/10 Very good (15 reviews) "Comfortable spacious room. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Norman CA $98 CA $127 total includes taxes & fees Apr 17 - Apr 18 [](https://www.expedia.ca/Serres-Hotels-Acropol.h13234890.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-19&endDate=2026-04-20®ionId=3000756489&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesadha-Hotels.d3000756489.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesadha-Hotels.d3000756489.Travel-Guide-Hotels) ## Top Mesadha Hotel Reviews ## Recent Reviews in Mesadha ![Philippos Xenia Hotel](https://images.trvl-media.com/lodging/74000000/73250000/73245700/73245692/f7982f66_y.jpg) ### Philippos Xenia Hotel 8/10 Good "Comfortable, good location. The corridors and the rooms could use some renovation. The breakfast was adequate but uninspiring" [](https://expedia.ca/Serres-Hotels-PHILIPPOS-XENIA-HOTEL.h73245692.Hotel-Information) ![Acropol](https://images.trvl-media.com/lodging/14000000/13240000/13234900/13234890/bd524f26_y.jpg) ### Acropol 10/10 Excellent "Comfortable spacious room. " [](https://expedia.ca/Serres-Hotels-Acropol.h13234890.Hotel-Information) ![Metropolis](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868833/ba08849c_y.jpg) ### Metropolis 10/10 Excellent "Good location, very clean, comfy bed." [](https://expedia.ca/Serres-Hotels-Metropolis.h1868833.Hotel-Information) ## More cheap stays in Mesadha ![Metropolis](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868833/ba08849c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Metropolis Dion. Solomou Str. - Emporiou Sq., 49 Serres Central Macedonia [Get rates](https://expedia.ca/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=1868833&PinnedHotelID=1868833&HadPinnedHotel=true®ionId=3000756489) 8/10 Very Good! (8 reviews) [](https://expedia.ca/Serres-Hotels-Metropolis.h1868833.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Mesadha? > This area is the heart of Mesadha, featuring a cluster of traditional tavernas and a few local shops. The square itself is a relaxed spot where locals gather, particularly in the evenings. You'll find accommodation options here range from charming guesthouses to small, family-run hotels, often with balconies offering views of the surrounding hills. > > > Couples looking for a quiet and authentic Greek village experience will find this area particularly appealing. It's ideal for enjoying leisurely meals, sampling local wines, and experiencing the relaxed pace of life. The central location means you're just a short walk from everything the village has to offer, making it easy to explore on foot. > > > For solo travellers seeking a peaceful retreat, staying near the main square offers a welcoming base. You can easily connect with locals at the tavernas and enjoy the serenity of the village. ### When is the best time to go to Mesadha? > During these months, the weather is pleasantly warm, ideal for exploring the region's historical sites and natural beauty without the intense heat or larger crowds of the peak summer months. You'll find comfortable temperatures for outdoor activities like hiking in the nearby mountains or visiting archaeological sites. > > > Couples looking for a relaxed yet engaging holiday will particularly enjoy Mesadha during these times. The quieter atmosphere allows for a more intimate experience at local tavernas and attractions. The sea temperatures are also comfortable enough for swimming in early summer and early autumn. > > > For travellers planning to combine cultural exploration with beach relaxation, early June and September are perfect. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Mesadha hotel booking with Expedia? ### How much is the nightly rate at a Mesadha hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Thessaloniki ](https://www.expedia.ca/5Star-Thessaloniki-Hotels.s50-0-d3186.Travel-Guide-Filter-Hotels) - [Agkistro Hotels ](https://www.expedia.ca/Agkistro-Hotels.d3000426930.Travel-Guide-Hotels) - [Akritochori Hotels ](https://www.expedia.ca/Akritochori-Hotels.d3000703166.Travel-Guide-Hotels) - [Áno Poróïa Hotels ](https://www.expedia.ca/Ano-Poroia-Hotels.d3000031445.Travel-Guide-Hotels) - [Anoixia Hotels ](https://www.expedia.ca/Anoixia-Hotels.d3000756476.Travel-Guide-Hotels) - [Arethousa Hotels ](https://www.expedia.ca/Arethousa-Hotels.d3000739578.Travel-Guide-Hotels) - 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