Medical District Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

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    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Medical District

Price found within the past 48 hours. Click for updated prices.
The Moose
Hotel Napoleon Memphis
Hotel Indigo Memphis Downtown by IHG
The Rambler
The Stallion

Where to stay in Medical District

Find the best Medical District areas and neighborhoods for the activities you enjoy most. Learn more about Medical District

Medical District Hotel Deals

Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown

2 out of 5
210 S Pauline St, Memphis, TN
Fully refundableReserve now, pay when you stay
The price is CA $67 per night from Aug 31 to Sep 1
CA $67
CA $83 total
Aug 31 - Sep 1
includes taxes & fees
Motel 6 Memphis, TN - Downtown
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue, Memphis, TN
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Sep 5 to Sep 6
CA $121
CA $150 total
Sep 5 - Sep 6
includes taxes & fees
8.4/10 Very Good! (1,375 reviews)
"This hotel is beautiful. The roof top is a great veiw of Memphis. It is a walkable distance between parking, stores, and restaurants. The satff were very welcoming as well. Check in and check out eeng smooth!!"

Reviewed on Aug. 23, 2025

Hu. Hotel
Sheraton Memphis Downtown Hotel

Sheraton Memphis Downtown Hotel

4 out of 5
250 N Main St, Memphis, TN
Fully refundableReserve now, pay when you stay
The price is CA $165 per night from Sep 13 to Sep 14
CA $165
CA $199 total
Sep 13 - Sep 14
includes taxes & fees
Sheraton Memphis Downtown Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Medical District vacation package cost?
Our Medical District packages, which start from just CA $1,148, are an easy way to save big bucks. All you have to do is choose your preferred hotels, flights and more to create your ideal trip.
How do I get a cheap travel package to Medical District?
Combine your bookings with Expedia to save big on your next adventure. With over 550 partner airlines and 1,000,000 hotel options worldwide, your Medical District vacation package can be customized exactly to suit your travel style. With all those extra dollars, why not include a few awesome experiences and tours? It's an easy way to unlock even more savings. That dream vacation to Medical District is much closer than you thought!
Where should I stay in Medical District?
Visitors come from near and far to experience Graceland and Memphis Zoo in Medical District. Book a hotel within walking distance of these popular attractions and visit them whenever you want.
What are the top hotels in Medical District?
Secure a room at Motel 6 Memphis, TN - Downtown. It's one of the area's most sought-after hotels. Another great option in Medical District is Downtown Memphis Shellcrest Apartments.
How far in advance should I book my Medical District vacation?
It's hard to pick the perfect time for airfares, but we generally suggest the earlier, the better. Most international journeys on Expedia become available to compare up to a year in advance. If you're unable to do so, don't fret. Cheap prices occasionally appear just weeks before departure dates.
What does an Expedia Medical District travel package include?
Hotels, flights and rental cars — you'll discover them all here. With Expedia, you can create your Medical District travel package just how you like it. All you have to do is figure out just what you need. Once you've made your booking, you can add extras like activities and experiences. The more you bundle, the bigger the savings!
What should I know before booking a Medical District travel package?
You'll score amazing savings when you combine your hotels, flights and rental cars into a package. Plus, booking everything in one spot makes trip planning much easier. So why waste your money or time? Whether you're organizing a luxury romantic escape or a low-cost family road trip, explore our package deals today.
Can I choose my airline with a Medical District Expedia vacation package?
Yes, the choice is all yours. We offer more than 550 airlines all over the world, so you can tailor your Medical District adventure according to your budget and needs.
If I'm not able to travel, can I cancel my Medical District vacation package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Medical District vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Check our Customer Service Portal to learn more.

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.