Title: Medical Center District Vacation Packages & Trips 2025 from CA $1,755 | Expedia.ca [Medical Center District Travel Guide](https://expedia.ca/San-Antonio-Medical-Center-District.dx553248635978913844)[Hotels in Medical Center District](https://expedia.ca/Medical-Center-District-San-Antonio-Hotels.0-n553248635978913844-0.Travel-Guide-Filter-Hotels)[Flights to San Antonio](https://expedia.ca/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)[Things to do in San Antonio](https://expedia.ca/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)[Medical Center District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-Center-District.d553248635978913844.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6193120/6208bc73-d0ab-4fda-b1af-d2c1bae086ed.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Medical Center District Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence ### Better together Save up to CA $1,096 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Plan, book, and manage your trip all in one place ## Top Holiday Package Deals in Medical Center District Price found within the past 48 hours. Click for updated prices. ![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW Medical Center District CA $973 per person Jan 12 - Jan 19 found 13 hours ago Roundtrip non-stop flight included Kelowna (YLW) to San Antonio (SAT) 8.6/10 Excellent! (3,018 reviews) not as expected, the room was moisty and we asked for change, ac was too noisy . Reviewed on Oct 29, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-01-12/2026-01-19/?FromAirport=YLW&Destination=SAT&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1613977&paandie=true&dealMarker=ZSIA1ErhvxTsG1XCOCx2NhcRi3KI4gzVJRD-WPIv-EG24fOlmOnd4pD2IuTP8pG1) ![Brand New Listing!cozy Historic House 5mindt](https://images.trvl-media.com/lodging/50000000/49280000/49270100/49270026/w2570h1900x156y0-96499e54_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Brand New Listing!cozy Historic House 5mindt Near East Side CA $6,498 per person Dec 22 - Dec 28 found 1 day ago Roundtrip non-stop flight included Edmonton (YEA) to San Antonio (SAT) 6/10 (4 reviews) [](https://expedia.ca/go/package/search/FlightHotel/2025-12-22/2025-12-28/?FromAirport=YEA&Destination=SAT&NumRoom=1&NumAdult=2&NumChild=0&hotelId=49270026&paandie=true&dealMarker=E26PuAQ6xXPf4DffYcXSR4dLsD7BAyyD2j1TXLK-BUI7RLB-I5LSV1NCFXmld93H) ![Hyatt Vacation Club at Wild Oak Ranch, San Antonio](https://images.trvl-media.com/lodging/2000000/1120000/1113200/1113168/5058d5ba_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Vacation Club at Wild Oak Ranch, San Antonio Far West Side CA $1,214 per person Jan 12 - Jan 19 found 13 hours ago Roundtrip non-stop flight included Kelowna (YLW) to San Antonio (SAT) 9/10 Wonderful! (1,129 reviews) Clean room, staff is very attentive, and the location is close to downtown, airport etc. Reviewed on Oct 28, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-01-12/2026-01-19/?FromAirport=YLW&Destination=SAT&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1113168&paandie=true&dealMarker=dv63z8oCuVKmBdZ-hTm6zqWsFwZ7rlMinnsC0dkdnAYBQXMIRzv1YsxzxSLZuuDM) ![Hyatt Regency Hill Country Resort and Villas](https://images.trvl-media.com/lodging/1000000/30000/21700/21664/fc712ef3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Regency Hill Country Resort and Villas Far West Side CA $1,815 per person Dec 22 - Dec 28 found 1 day ago Roundtrip non-stop flight included Edmonton (YEA) to San Antonio (SAT) 8.8/10 Excellent! (1,011 reviews) The staff should learn a little bit more about each other’s function. A basic question such as the opening and closing time of another amenities should not need to require a transfer. Reviewed on Oct 19, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-22/2025-12-28/?FromAirport=YEA&Destination=SAT&NumRoom=1&NumAdult=2&NumChild=0&hotelId=21664&paandie=true&dealMarker=RBO2iA3vbszIeX9r9VC77_JHcuw0_nHnRYRWXUP5p3o9pT-L3xSmdR5m8Sp9Nz_3) ![Tapatio Springs Hill Country Resort](https://images.trvl-media.com/lodging/1000000/20000/19900/19838/09724f60_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Tapatio Springs Hill Country Resort CA $1,755 per person Dec 22 - Dec 28 found 1 day ago Roundtrip non-stop flight included Edmonton (YEA) to San Antonio (SAT) 8.6/10 Excellent! (823 reviews) The front desk staff was amazing. We had some extra special needs and they accommodated us immediately and went above and beyond our ask. Had a small maintenance issue and it was tended to very quickly and timely. Great stay, could not have asked for a better place to celebrate our 2nd anniversary. Thank you! Reviewed on Oct 28, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-22/2025-12-28/?FromAirport=YEA&Destination=SAT&NumRoom=1&NumAdult=2&NumChild=0&hotelId=19838&paandie=true&dealMarker=RBO2iA3vbszIeX9r9VC771l49CS-z8OP14IXg5-X4V1fa2WyurOM3rXyHf0xgkXp) ## Where to stay in Medical Center District Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. [Learn more about Medical Center District](https://expedia.ca/San-Antonio-Medical-Center-District.dx553248635978913844) ![Downtown - Riverwalk showing heritage architecture, boating and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34785-San-Antonio-Rverwalk.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown San Antonio 4 out of top 10 points of interest in this area 4/5(209 area reviews) Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit. [Find hotel + flight trips in Downtown San Antonio](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20San%20Antonio&DestID=800120&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/535000/535610-marion-koogler-mcnay-art-museum.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Uptown While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market. [Find hotel + flight trips in Uptown](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Uptown&DestID=553248635974902947&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://mediaim.expedia.com/destination/1/32d4867af6fd75a081e8873eb60c7c86.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Far West Side 1 out of top 10 points of interest in this area While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club. [Find hotel + flight trips in Far West Side](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Far%20West%20Side&DestID=553248635975749416&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Stone Oak 4/5(3 area reviews) Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town. [Find hotel + flight trips in Stone Oak](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Stone%20Oak&DestID=6343068&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Northwest Side While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center. [Find hotel + flight trips in Northwest Side](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Northwest%20Side&DestID=887264728595001344&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ## Medical Center District Hotel Deals ![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW 4431 Horizon Hill Blvd, San Antonio, TX Fully refundableReserve now, pay when you stay CA $124 CA $146 total Oct 30 - Oct 31 includes taxes & fees 8.4/10 Very Good! (3,022 reviews) Clean Reviewed on Oct 27, 2025 [](https://expedia.ca/Hotel-Search?startDate=30%2F10%2F2025&endDate=31%2F10%2F2025&selected=1613977&PinnedHotelID=1613977&HadPinnedHotel=true®ionId=553248635978913844) ![San Antonio Marriott Northwest Medical Center](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/aa83e7de_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Antonio Marriott Northwest Medical Center 3233 NW Loop 410, San Antonio, TX Fully refundableReserve now, pay when you stay CA $124 CA $147 total Nov 14 - Nov 15 includes taxes & fees 8.6/10 Excellent! (1,014 reviews) Everything was good Reviewed on Oct 27, 2025 [](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=4192&PinnedHotelID=4192&HadPinnedHotel=true®ionId=553248635978913844) ![Fairfield Inn & Suites by Marriott San Antonio Medical Center](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/3a049706_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott San Antonio Medical Center 7203 Wurzbach Road, San Antonio, TX Fully refundableReserve now, pay when you stay CA $123 CA $143 total Nov 16 - Nov 17 includes taxes & fees 9/10 Wonderful! (1,022 reviews) Breakfast is always great and hotel is always clean and relaxing Reviewed on Oct 27, 2025 [](https://expedia.ca/Hotel-Search?startDate=16%2F11%2F2025&endDate=17%2F11%2F2025&selected=68847371&PinnedHotelID=68847371&HadPinnedHotel=true®ionId=553248635978913844) [See all 4,630 properties in Medical Center District](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=30%2F10%2F2025&endDate=31%2F10%2F2025®ionId=553248635978913844) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Frequently asked questions ### How much does a Medical Center District vacation package cost? > Starting from just CA $973, a vacation package is your passport to low-priced travel. Create your own Medical Center District adventure by picking from our huge range of airfares, hotels and rental cars. ### How do I get a cheap travel package to Medical Center District? > It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Center District vacation package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your vacation your own way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has a chance to travel and fulfill those vacation dreams. ### Where should I stay in Medical Center District? > Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers. ### What are the top hotels in Medical Center District? > [Amazing, Contemporary, Beautiful](https://www.expedia.ca/San-Antonio-Hotels-Amazing.h59121121.Hotel-Information) and [Fairfield Inn & Suites by Marriott San Antonio Medical Center](https://www.expedia.ca/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information) are two of the most well-known hotels in Medical Center District. Why not take a look at the amenities and rates at each and then make up your mind? ### How far in advance should I book my Medical Center District vacation? > It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure. ### What does an Expedia Medical Center District travel package include? > Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Center District vacation. ### What should I know before booking a Medical Center District travel package? > You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between! ### Can I choose my airline with a Medical Center District Expedia vacation package? > Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Center District trip according to your budget and travel needs. ### If I'm not able to travel, can I cancel my Medical Center District vacation package? > Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Center District vacation package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our [Customer Service Portal](https://www.expedia.ca/service/?langid=4105). We're here to help you every step of the way. ### Discover the most popular places to visit in Medical Center District #### USAA Corporate Office Headquarters USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area. [](https://expedia.ca/USAA-Corporate-Office-Headquarters-Medical-Center-District.d553248621593511346.Vacation-Attraction) ### Things to do ![San Antonio: San Antonio Zoo Any Day Ticket](https://mediaim.expedia.com/localexpert/45080165/27b80936-95ea-4267-8f56-004cd1e3d031.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Antonio: San Antonio Zoo Any Day Ticket CA $41 per adult **94%** of travellers recommend [](https://expedia.ca/things-to-do/san-antonio-san-antonio-zoo-any-day-ticket.a45080165.activity-details) ![SEA LIFE San Antonio](https://mediaim.expedia.com/localexpert/2625586/aff922c4-5e56-43ba-b29c-d3f4f80218e7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### SEA LIFE San Antonio CA $35 per adult **78%** of travellers recommend [](https://expedia.ca/things-to-do/sea-life-san-antonio.a2625586.activity-details) [See all activities in San Antonio](https://expedia.ca/things-to-do/search?rid=553248635978913844) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.