Title: Book the Best Lower Florida Keys LUXURY Hotels - Upscale Hotels in Lower Florida Keys, FL | Expedia.ca [Lower Florida Keys Travel Guide](https://expedia.ca/Lower-Florida-Keys.dx553248635975748710)[Hotels in Lower Florida Keys](https://expedia.ca/Lower-Florida-Keys-Hotels.d553248635975748710.Travel-Guide-Hotels)[Vacation Rentals in Lower Florida Keys](https://expedia.ca/Lower-Florida-Keys-Vacation-Rentals.d553248635975748710.Travel-Guide-VacationRentals)[Flights to Lower Florida Keys](https://expedia.ca/Cheap-Flights-To-Lower-Florida-Keys.d553248635975748710.Travel-Guide-Flights)[Things to do in Lower Florida Keys](https://expedia.ca/Things-To-Do-In-Lower-Florida-Keys.d553248635975748710.Travel-Guide-Activities)[Lower Florida Keys Car Rentals](https://expedia.ca/Car-Rentals-In-Lower-Florida-Keys.d553248635975748710.Car-Rental-Guide)[Lower Florida Keys Vacation Packages](https://expedia.ca/Lower-Florida-Keys.d553248635975748710.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63795-Florida-Keys.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Lower Florida Keys, FL ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lower Florida Keys Luxury Hotels Tonight [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975748710&startDate=2025-10-25&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=553248635975748710&startDate=2025-10-26&endDate=2025-10-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975748710&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975748710&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Lower Florida Keys Luxury Hotels ## Find out more about Lower Florida Keys ### Lower Florida Keysand its attractions for luxury travelers The Lower Florida Keys offer a unique blend of natural beauty and luxurious experiences, perfect for discerning travellers. Start your adventure at the stunning Dry Tortugas National Park, where you can explore the historic Fort Jefferson and snorkel among vibrant coral reefs in crystal-clear waters. For those who appreciate fine dining, the upscale restaurants in Key West serve fresh seafood caught daily, allowing you to savour the flavours of the region while enjoying ocean views. A visit to the iconic Seven Mile Bridge presents breathtaking vistas, perfect for a leisurely drive or a romantic sunset stroll. Thrill-seekers can indulge in a private sailing charter, where you can enjoy personalised service while gliding over the turquoise waters, perhaps spotting dolphins along the way. For a truly opulent stay, consider the luxurious resorts in Key Largo, which offer lavish amenities such as private beachfronts, infinity pools, and exclusive spa services – ensuring that your every need is met as you unwind in this tropical paradise. The combination of adventure and relaxation in the Lower Florida Keys makes for an unforgettable getaway. ## Top Lower Florida Keys Hotel Reviews ![Looe Key Reef Resort](//images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/63d12f01_y.jpg) ### Looe Key Reef Resort 8/10 Good "We enjoyed our three night stay. We dived Looe Key reef every day through their dive shop. Safe shallow diving with excellent storage, easy access and excellent staff. Left the afternoon/evening open to relax or go into town. About 50 minutes from Key West. Recommend car rental for your stay" [](https://expedia.ca/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information) ![Parmer's Resort](//images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/6492712a_y.jpg) ### Parmer's Resort 10/10 Excellent "Everything was sweet! Clean, breakfast good, property organized and boys at front desk very nice and polite! Excellent! Will definitely consider going back" [](https://expedia.ca/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information) ![Sugar Loaf Lodge](//images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/95d2903e_y.jpg) ### Sugar Loaf Lodge 10/10 Excellent "This was an excellent value for the price - the room was spacious and clean, the property was quiet. There was a beautiful view with a balcony. I could not have been happier with my experience!" 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[Winery Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Winery-Hotel.0-n553248635976481798-0-tWineryHotel.Travel-Guide-Filter-Hotels) - [Book Luxury Hotels in Lower Florida Keys on Expedia.com](https://www.expedia.com/Lower-Florida-Keys-Hotels-Luxury-Hotel.0-0-d553248635975748710-tLuxuryHotel.Travel-Guide-Filter-Hotels)