A coastal promenade with palm trees, a sandy path, a bench, a playground, and a hotel in the background.

La Serena Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for La Serena vacation rentals

1. Apart Hotel y Cabañas Vegasur

Apart Hotel y Cabañas Vegasur
3.0 star property
La Serena
8.6 out of 10, Excellent, (96 reviews)
"Clean place, friendly staff, beach near, kitchen, and walking distance to nice restaurants and to enjoy the sunset and sunrise. Great location"
United States
Sandra
The price is CA $68
CA $68 total
Sep 3 - Sep 4
Apart Hotel y Cabañas Vegasur

2. Cabañas MarSerena

Cabañas MarSerena
3.5 star property
La Serena
9.0 out of 10, Wonderful, (53 reviews)
"very nice place to stay close to the beach, reasonably price and everybody there was very very pleasant"
United States
JOHN
The price is CA $69
CA $69 total
Aug 27 - Aug 28
Cabañas MarSerena

3. Domos Dream hotel cabañas

Domos Dream hotel cabañas
2.0 star property
La Serena
8.6 out of 10, Excellent, (4 reviews)
"It was far away."
Mexico
Sergio
The price is CA $110
CA $110 total
Sep 1 - Sep 2
Domos Dream hotel cabañas

4. Apart Hotel Gran Pacifico

Apart Hotel Gran Pacifico
3.0 star property
La Serena
8.6 out of 10, Excellent, (40 reviews)
"En gral buena eleccion"
Argentina
Javier
The price is CA $125
CA $125 total
Aug 27 - Aug 28
Apart Hotel Gran Pacifico

5. Beautiful apartment on the beach

Beautiful apartment on the beach
Coquimbo
10.0 out of 10, Exceptional, (1 review)
"The property is right on the beach with a huge pool. The parking is gated and secure. There is a walking bridge right beside the building to let you cross the busy highway so you can access restaurants. The host was very accommodating and helpful. The carpets in the hallway were really stained, but that was our only complaint. We had a good stay in a lovely location."
Canada
Layla
The price is CA $94
CA $141 total
Sep 7 - Sep 8
Beautiful apartment on the beach

6. La Choza VIP Turquesa en La Serena

La Choza VIP Turquesa en La Serena
3.0 star property
Coquimbo
7.8 out of 10, Good, (12 reviews)
"The apartment was very good for my needs and close to the conference centre. Safe, clean, well appointed. Yanitza was a big help and responsive to WhatsApp messages."
Canada
Andrew
The price is CA $115
CA $115 total
Sep 24 - Sep 25
La Choza VIP Turquesa en La Serena

7. ELDEPTO LA SERENA

ELDEPTO LA SERENA
3.0 star property
Coquimbo
8.0 out of 10, Very good, (2 reviews)
"Boa localização de fácil acesso, tranquilidade e bom atendimento"
Brazil
Ricardo Horacio
The price is CA $63
CA $63 total
Aug 28 - Aug 29
ELDEPTO LA SERENA

8. 2nd Floor WiFi La Serena Beach & Casino!

2nd Floor WiFi La Serena Beach & Casino!
Coquimbo
10.0 out of 10, Exceptional, (1 review)
"Excelente departamento, ubicación y comodidad, muchas gracias Yanitza por todo!!! Esperamos volver pronto!"
United States
Daniela
The price is CA $115
CA $198 total
Aug 27 - Aug 28
2nd Floor WiFi La Serena Beach & Casino!

9. "Nicoland" Playa, piscina, La Serena

"Nicoland" Playa, piscina, La Serena
La Serena
10.0 out of 10, Exceptional, (1 review)
"Hermoso departamento,muy bien amoblado, no le falta nada. Excelente ubicación. Queremos destacar la atención de la anfitriona Yanitza, quien siempre estuvo atenta a todas nuestras necesidades y consultas. De seguro volveremos!"
United States
Daniela
The price is CA $111
CA $194 total
Aug 27 - Aug 28
"Nicoland" Playa, piscina, La Serena

10. Trabajo y Relax VIP en La Serena

Trabajo y Relax VIP en La Serena
La Serena
The price is CA $75
CA $116 total
Sep 24 - Sep 25
Trabajo y Relax VIP en La Serena

11. Elegant apartment in a privileged location in the heart of Avenida del Mar.

Elegant apartment in a privileged location in the heart of Avenida del Mar.
La Serena
8.0 out of 10, Very good, (1 review)
"The building is nice because it is conveniently located near the beach and lots of shops and restaurants. It was easy to locate the tower and room we rented. The rooms were clean, but the apartment and all bedding smelled of smoke. I am not a smoker so this was unexpected and disappointing. Also, the noise level is quit high because the walls are very thin."
United States
Elena
The price is CA $131
CA $213 total
Sep 7 - Sep 8
Elegant apartment in a privileged location in the heart of Avenida del Mar.

12. Beach, breezes and sea Beautiful and comfortable apartment with exceptional location.

Beach, breezes and sea Beautiful and comfortable apartment with exceptional location.
Coquimbo
The price is CA $65
CA $140 total
Aug 27 - Aug 28
Beach, breezes and sea Beautiful and comfortable apartment with exceptional location.

13. Depto Serena Golf

Depto Serena Golf
2.0 star property
La Serena
The price is CA $286
CA $377 total
Aug 28 - Aug 29
Depto Serena Golf

14. Coquimbo from the heights, sea view+panoramic swimming pool, autonomous arrival24/7

Coquimbo from the heights, sea view+panoramic swimming pool, autonomous arrival24/7
Coquimbo
The price is CA $75
CA $138 total
Aug 27 - Aug 28
Coquimbo from the heights, sea view+panoramic swimming pool, autonomous arrival24/7

15. Apt 107D Jardines del Pacifico IV

Apt 107D Jardines del Pacifico IV
La Serena
The price is CA $80
CA $109 total
Aug 27 - Aug 28
Apt 107D Jardines del Pacifico IV

16. Comfortable apartment In coquimbo with parking space

Comfortable apartment In coquimbo with parking space
Coquimbo
The price is CA $65
CA $94 total
Sep 3 - Sep 4
Comfortable apartment In coquimbo with parking space

17. Cabañas en la naturaleza del Río Elqui

Cabañas en la naturaleza del Río Elqui
2.5 star property
Vicuña
The price is CA $137
CA $137 total
Aug 27 - Aug 28
Cabañas en la naturaleza del Río Elqui

18. Cabañas Yunkai

Cabañas Yunkai
3.0 star property
Vicuña
The price is CA $106
CA $106 total
Sep 21 - Sep 22
Cabañas Yunkai

19. Yunkai Home

Yunkai Home
2.0 star property
Vicuña
2.0 out of 10, (1 review)
The price is CA $98
CA $98 total
Aug 27 - Aug 28
Yunkai Home

20. Playa Blanca Resort

Playa Blanca Resort
2.5 star property
Coquimbo
6.0 out of 10, (2 reviews)
"The view was amazing. Property was well kept."
United States
claudia
The price is CA $97
CA $97 total
Sep 6 - Sep 7
Playa Blanca Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top La Serena Hotel Reviews

Find out more about La Serena

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with La Serena. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in La Serena?

Yes, we give you a choice of vacation rentals in La Serena near Jardin del Corazon, or you can go with a more remote option if you're looking for a relaxing stay. La Serena is known for its sightseeing tours and spas. Make sure you have time to check out the casinos while you're in the area.

What are some of the best vacation rentals in La Serena?

Parcela 20 Sector San Ramón: This La Serena vacation home rental offers a terrace, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and kitchenware, so you can cook with friends or family. Other favorite homes for rent in La Serena are lagoon beach marina 312 and lagoon beach white 803.

How many vacation rentals will I find in La Serena?

With 47 Expedia vacation rentals, you're sure to find just the right place for your La Serena stay.

What can I see and do in La Serena?

Cultural attractions include President Gabriel González Videla Regional History Museum and Casa Gabriel Gonzalez Videla Historical Museum, whereas Kokoro No Niwa Japanese Garden and La Serena Beach are a couple of picturesque spots to enjoy the outdoors. While here, Mall Plaza La Serena and La Serena Lighthouse are other places worth a visit.

What are vacation rentals like in La Serena?

Vacation rentals are private accommodations you can reserve for a short or long stay in La Serena. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family trip.