Name: Comfort Suites Jackson-Cape Girardeau
Price range: CA $133
Rating: 8.2

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Your Jackson Vacation

Take the worry out of planning your next great adventure with a Jackson vacation package. Whether you're visiting for its cuisine, history, art or something else, this city offers limitless opportunities for discovery. Cape Girardeau Conservation Nature Center, Lazy L Safari Park and Steele Crest Winery are just a few of the many attractions worth visiting during your trip to Jackson. Expedia is here to help you escape the everyday. Tailor your vacation to Jackson to suit your travel style, whatever that may look like.

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Jackson Hotel Deals

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3003 SOUTH OLD ORCHARD ROAD Jackson MO

Fully refundableReserve now, pay when you stay

CA $132

CA $143 total

Jul 1 - Jul 2

includes taxes & fees

9/10 Wonderful! (787 reviews)

"Clean, quiet and friendly. It is why I always stay here when I am in the area."

Reviewed on Jun 23, 2026

Drury Inn & Suites Jackson MO

225 Drury Lane Jackson MO

Fully refundableReserve now, pay when you stay

CA $121

CA $128 total

Jun 28 - Jun 29

includes taxes & fees

9.6/10 Exceptional! (1,000 reviews)

"Our stay has been top-notch!!!! Super clean, food was amazing!!!! Breakfast you want for nothing with so many options and absolutely wonderful!! Kickback was a very nice surprise. Again options so great and food amazing!!! Staff was super helpful and really care about their jobs!!!! Ten stars!!!! ..."

Reviewed on Jun 22, 2026

Comfort Suites Jackson-Cape Girardeau

2904 Old Orchard Rd Jackson MO

Fully refundable

CA $133

CA $143 total

Jun 28 - Jun 29

includes taxes & fees

8.2/10 Very good! (771 reviews)

"We stayed at Comfort Suites in Jackson, Missouri, for two nights and had a very pleasant experience overall. The rooms could use a few cosmetic updates and minor touch-ups, but they were clean, comfortable, and well-maintained where it mattered most. The staff was friendly, welcoming, and helpful ..."

Reviewed on Jun 21, 2026

See all 259 properties in Jackson

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.