Title: Book the Best Isla Grande SPA Resorts from CA $748 - Spa Hotels in Isla Grande | Expedia.ca [Hotels in Isla Grande](https://expedia.ca/Isla-Grande-Hotels.d6053183.Travel-Guide-Hotels)[Vacation Rentals in Isla Grande](https://expedia.ca/Isla-Grande-Vacation-Rentals.d6053183.Travel-Guide-VacationRentals)[Flights to Isla Grande](https://expedia.ca/Cheap-Flights-To-Isla-Grande.d6053183.Travel-Guide-Flights)[Isla Grande Car Rentals](https://expedia.ca/Car-Rentals-In-Isla-Grande.d6053183.Car-Rental-Guide)[Isla Grande Vacation Packages](https://expedia.ca/Isla-Grande.d6053183.Destination-Travel-Guides) ![Palm trees forest and houses in Isla Grande shore. Colon province, Panama, Caribbean, Central America.](https://images.trvl-media.com/place/6053183/8bba6d27-3102-43e6-89e4-9ef59409f2b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6053183/8bba6d27-3102-43e6-89e4-9ef59409f2b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Isla Grande Spa Hotels Tonight [Feb 16 - Feb 17](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-02-16&endDate=2026-02-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 17 - Feb 18](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-02-17&endDate=2026-02-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-02-20&endDate=2026-02-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-02-27&endDate=2026-03-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isla Grande hotels with a spa ![Luxury Suite](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/9a39b281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/c9b59f2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Ocean View](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/81e41030.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/013d70fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ordovician Beach Resort [](https://www.expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information) Isla Grande 10/10 Exceptional (8 reviews) "The best service in Panama!!! We truly felt cared for in every detail — the team is attentive, warm, and genuinely professional. The food was outstanding: the chef is exceptional! Every dish reflected passion, quality, and pride. This hotel is located on a beautiful Caribbean island, surrounded by untouched nature, turquoise waters, and a truly magical atmosphere. What made it even more special was the silence and privacy — only the sound of the waves and the singing of birds!) A wonderful... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yevhen CA $680 CA $748 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information) ![Sauna, steam room](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/0f5b4937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | View from room](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/ada335d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, free beach shuttle, beach bar](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/dcd510f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/272cbe65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ciel y Miel [](https://www.expedia.ca/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) Cacique 10/10 Exceptional (10 reviews) "Love this place and would return back numerous times" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean [](https://www.expedia.ca/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-03&endDate=2026-03-04®ionId=6053183&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Isla Grande Pool Breakfast included Hot tub 4 stars 5 stars ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AFFINITY_SPRING_PROMO_6053183) ## Top Isla Grande Hotel Reviews ## Frequently asked questions ### Looking for a spa hotel in Isla Grande? ### What is the best spa hotel in Isla Grande? ### How many spa hotels will I find in Isla Grande? ### What's there to see and do in Isla Grande? ### What is a Isla Grande spa hotel?