Title: Book the Best BUSINESS Hotels in Sister Islands in 2025 | Expedia.ca

 

[Sister Islands Travel Guide](https://expedia.ca/Sister-Islands.dx553248633946460050)[Hotels in Sister Islands](https://expedia.ca/Sister-Islands-Hotels.d553248633946460050.Travel-Guide-Hotels)[Vacation Rentals in Sister Islands](https://expedia.ca/Sister-Islands-Vacation-Rentals.d553248633946460050.Travel-Guide-VacationRentals)[Flights to Sister Islands](https://expedia.ca/Cheap-Flights-To-Sister-Islands.d553248633946460050.Travel-Guide-Flights)[Sister Islands Car Rentals](https://expedia.ca/Car-Rentals-In-Sister-Islands.d553248633946460050.Car-Rental-Guide)[Sister Islands Vacation Packages](https://expedia.ca/Sister-Islands.d553248633946460050.Destination-Travel-Guides)

![#Endlesssummer Great wall diving on Little Cayman. Colorful sponges, lots of fish and beautiful tropical waters.](https://images.trvl-media.com/place/6307499/8505b9ac-5e4b-4d71-9462-2667bf474e3e.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Bob Bowdey

# Find Business Hotels in Sister Islands from CA $383

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## Check availability on Sister Islands Business Hotels

Tonight

[Nov 28 - Nov 29](https://www.expedia.ca/Hotel-Search?regionId=553248633946460050&startDate=2025-11-28&endDate=2025-11-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Nov 29 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248633946460050&startDate=2025-11-29&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248633946460050&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248633946460050&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Top Sister Islands Business Hotels

No exact matches found, but these alternatives could be just right

## Recommended hotels in Sister Islands

![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/72668cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/5c796649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/ed137e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![The Coast House | Living area](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/864ef166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Le Soleil d'Or CaymanBrac

West End

9.4/10

Exceptional

(13)

"We love this property!! The service is outstanding and the staff is lovely. 100% recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Silvana

CA $331

CA $484 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/George-Town-Hotels-Le-Soleil-DOr-CaymanBrac.h74421869.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/065d18cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/2e7351ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/178835fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45480000/45473300/45473215/201ded24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Alexander Suites - #103 Queen Suite

West End

8.8/10

Excellent

(3)

"I'd like to see more locals working at the Alexander. The cleaner lady was the friendliest person there, love her. The rooms could use an update in furniture and kitchenware / appliances"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

CA $245

CA $383 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/West-End-Hotels-The-Alexander-Suites-103-Queen-Suite.h45473215.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/f420876d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/f5464aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/b6c8f347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/50000000/49010000/49000400/49000374/ad002b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Alexander # 210 - Queen Suite

West End

9.4/10

Exceptional

(3)

"Great restaurant and bar on site. Staff are superb. The best place to stay on Cayman Brac!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew

CA $245

CA $387 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/West-End-Hotels-The-Alexander-210-Queen-Suite.h49000374.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/6a91b423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/523f8ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/0767edcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45530000/45522100/45522008/20c660a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Alexander Suites #102 - Double Queen

West End

10/10

Exceptional

(1)

"This was the perfect place for our short Cayman Brac trip. Next time we will stay longer. Absolutely no negative comments…highly recommend😃"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barbara B.

CA $316

CA $476 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/West-End-Hotels-The-Alexander-Suites-102-Double-Queen.h45522008.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/7ccf8361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/3d0e4f0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/f93dae03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/47000000/46110000/46108100/46108028/8a928cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Alexander - # 105 Queen Suite

West End

CA $245

CA $383 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/West-End-Hotels-The-Alexander-105-Queen-Suite.h46108028.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/05e5b681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/5ca749d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/43b985a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/47000000/46110000/46108700/46108602/1766a27b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Alexander - #201 2 Bedroom Suite

West End

10/10

Exceptional

(2)

"Excellent staff, restaurant was nice."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sandy

CA $369

CA $589 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/West-End-Hotels-The-Alexander-201-2-Bedroom-Suite.h46108602.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-13&regionId=553248633946460050&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

Black Friday Sale

Limited-time deals: save up to 50% on select hotels

[Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_553248633946460050)

## Top Sister Islands Hotel Reviews