Title: Santa Fe Island Vacation Home Rentals from CA $153: Search Top Private Vacation Homes for Rent | Expedia.ca [Santa Fe Island Travel Guide](https://expedia.ca/Santa-Fe-Island.dx6336630)[Hotels in Santa Fe Island](https://expedia.ca/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels)[Vacation Rentals in Santa Fe Island](https://expedia.ca/Santa-Fe-Island-Vacation-Rentals.d6336630.Travel-Guide-VacationRentals)[Flights to Santa Fe Island](https://expedia.ca/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights)[Santa Fe Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe-Island.d6336630.Car-Rental-Guide)[Santa Fe Island Vacation Packages](https://expedia.ca/Santa-Fe-Island.d6336630.Destination-Travel-Guides) ![Seal lions 😍 #aquatrove](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Elizabeth Oates ![](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2026-02-06&endDate=2026-02-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 15 - May 17](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Fe Island vacation homes ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f0249e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/5b0760b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/2475343d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f1c0fb19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos [](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information) Puerto Ayora 10/10 Exceptional (1 review) "Nice and beautiful house to stay very impressed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $125 CA $153 total Jan 21 - Jan 22 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/910a26ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/59b60aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/cc633cda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/6cb34f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jardin de Galápagos. [](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information) Galápagos Islands CA $94 CA $167 total Feb 2 - Feb 3 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/6e3cf51a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/84bd8893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/f20e4de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/247eabf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Life Two-Bedroom Galapagos Casita [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) Puerto Ayora 10/10 Exceptional (3 reviews) "We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Victoria K. CA $215 CA $276 total Jan 23 - Jan 24 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/192b9595.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/c866cc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/c0869485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/0f20952b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Imagination Studio Home [](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h124393435.Hotel-Information) Puerto Ayora CA $244 CA $309 total Jan 27 - Jan 28 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h124393435.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/937eb7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/50fe223c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/3ba85021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/89f46e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island life Duplex great for groups [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information) Puerto Ayora, Santa Cruz Island CA $389 CA $498 total Jan 26 - Jan 27 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information) ![6 bedrooms, WiFi](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/w1277h900x0y0-38edf997.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bedrooms, WiFi](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/38c2bf2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bedrooms, WiFi](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/9cc38edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bedrooms, WiFi](https://images.trvl-media.com/lodging/125000000/124600000/124595200/124595164/w1186h900x0y0-4fc9bb3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 6-bedroom building in superb Puerto Ayora with AC [](https://www.expedia.ca/Puerto-Ayora-Hotels-Spacious-6-Bedroom-Building-In-Superb-Puerto-Ayora-With-AC.h124595164.Hotel-Information) Puerto Ayora CA $44 CA $79 total Jan 21 - Jan 22 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Spacious-6-Bedroom-Building-In-Superb-Puerto-Ayora-With-AC.h124595164.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/753f38a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/b574e039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/46b3f49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Two Bedroom house - The Galapagos Pearl Hotel [](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information) Puerto Ayora 10/10 Exceptional (1 review) "We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura E. CA $278 CA $350 total Jan 21 - Jan 22 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/1f94b12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/369f220c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome, 1 Bedroom, Non Smoking, City View](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2847ed9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome, 1 Bedroom, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/50aec426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Galapagos [](https://www.expedia.ca/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information) Puerto Ayora 6.0/10 (1 review) "着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。" ![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg) アオアシカツオドリ [](https://www.expedia.ca/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04®ionId=6336630&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=APART_HOTEL) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=APARTMENT) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=VACATION_HOME) Villas [](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=VILLA) Condos [](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=CONDO) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador®ionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=CABIN) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Island-Private-Vacation-Homes.d6336630-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Island-Private-Vacation-Homes.d6336630-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Santa Fe Island Hotel Reviews ![Ikala Galapagos Hotel](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed_y.jpg) ### Ikala Galapagos Hotel 10/10 Excellent "The rooms are spacious and the hotel is centrally located. Puerto Ayora is a very pleasant place to visit. The Ikala hotel was a great base for an exciting zgalapagos adventure!" [](https://expedia.ca/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Hotel Ninfa](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e_y.jpg) ### Hotel Ninfa 10/10 Excellent "Excellent room, clean and spacious. The addition of the welcome basket was a lovely touch. Friendly staff and an excellent breakfast." [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Hotel Palace Galapagos](https://images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/48760e17_y.jpg) ### Hotel Palace Galapagos 10/10 Excellent "Our stay was great! The rooms were spacious and very clean! There was even has a back patio with a table and chairs. The interior courtyard was cute and I liked that our room was right off of the courtyard.They provided towels for the beach which was very nice. We would recommend this hotel to anyone and would definitely stay here again! " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Palace-Galapagos.h11050675.Hotel-Information) ![Angermeyer Waterfront Inn](https://images.trvl-media.com/lodging/5000000/4890000/4884900/4884897/9d038793_y.jpg) ### Angermeyer Waterfront Inn 10/10 Excellent "Staff very friendly and helpful. Comfortable room." [](https://expedia.ca/Puerto-Ayora-Hotels-Angermeyer-Waterfront-Inn.h4884897.Hotel-Information) ![Galapagos Verde Azul](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/6a115ff5_y.jpg) ### Galapagos Verde Azul 10/10 Excellent "We had an awesome time and everyone was so nice and helpful. The one thing I wish there was, was a tall mirror I could see my whole body/outfit in." [](https://expedia.ca/Puerto-Ayora-Hotels-Galapagos-Verde-Azul.h9577577.Hotel-Information) ![Posada del Mar](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1_y.jpg) ### Posada del Mar 10/10 Excellent "I wish i can give 7 stars. The check in and check out process are seamless, The room are facilities are very clean, the owner Carlos is super nice, when i needed to go to airport, he kindly helped me find a taxi to the local bus station. Breakfast is very healthy and balanced. I enjoyed the stay here. " [](https://expedia.ca/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) ![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg) ### Capitan Max B&B 10/10 Excellent "We stayed here for 3 nights while we were in Sta Cruz. The place was really nice and spacious rooms, very clean, complete facilities with nice little touches such as line to dry your clothes, usb sockets, and a hammock. The place looks the same in the photos. Max and his family were very welcoming and helpful and responsive. He helped us find tours and gave us tips to do and see in the island. The locations is also great. Few minutes walk to the Charles Darwin street, so you are in the centre but without the noise. We definitely recommend!" [](https://expedia.ca/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Maidith Galapagos Inn](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/1dd0538f_y.jpg) ### Maidith Galapagos Inn 10/10 Excellent "Great place! Incredibly friendly and kind staff. " [](https://expedia.ca/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information) ![Finch Bay Galapagos Hotel](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762_y.jpg) ### Finch Bay Galapagos Hotel 10/10 Excellent "The staff couldn’t have done more for us the hotel was stunning. Five star throughout. It’s expensive but so worth it " [](https://expedia.ca/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) ## Find out more about Santa Fe Island ## Santa Fe Island Vacation Homes information | Number of reviews | 4 | | ----------------- | ----------------- | | Accommodation | 19 Vacation Homes | | Lowest Price | CA $153 | | Highest Price | CA $498 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Baltra Hotels ](https://www.expedia.ca/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Bellavista ](https://www.expedia.ca/Bellavista-Hotels-LGBT-Friendly-Hotel.0-0-d6342722-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bellavista Hotels ](https://www.expedia.ca/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - [Apartments in Daphne Islands ](https://www.expedia.ca/Daphne-Islands-Apartments.d6336492-aaApartments.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Galápagos ](https://www.expedia.ca/Destinations-In-Galapagos-All-Inclusive-Hotel.0-0-d1371-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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