Title: Santa Cruz Island Vacation Home Rentals : Search Top Private Vacation Homes for Rent | Expedia.ca [Santa Cruz Island Travel Guide](https://expedia.ca/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Vacation-Rentals.d6053670.Travel-Guide-VacationRentals)[Flights to Santa Cruz Island](https://expedia.ca/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.ca/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-Island.d6053670.Car-Rental-Guide)[Santa Cruz Island Vacation Packages](https://expedia.ca/Santa-Cruz-Island.d6053670.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/04d5e478ee175ffd174b1e23d51916f4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Santa Cruz Island Vacation Rentals - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-11-21&endDate=2025-11-23&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-12-05&endDate=2025-12-07&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2026-01-02&endDate=2026-01-04&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Santa Cruz Island Vacation Homes ![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f1c0fb19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/2475343d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/e79a3386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/6f52aa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos Puerto Ayora 10/10 Exceptional (1) "Nice and beautiful house to stay very impressed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $157 CA $185 total Nov 11 - Nov 12 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information) ![Microwave, oven](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/6cb34f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/910a26ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/e5fb900f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/4e0bcac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jardin de Galápagos. Galápagos Islands CA $95 CA $169 total Nov 11 - Nov 12 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/937eb7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/3ba85021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/89f46e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/ba5f6360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island life Duplex great for groups Puerto Ayora, Santa Cruz Island CA $393 CA $506 total Dec 3 - Dec 4 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/6e3cf51a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/9f903199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/f20e4de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/84bd8893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Life Two-Bedroom Galapagos Casita Puerto Ayora 10/10 Exceptional (3) "We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Victoria K. CA $218 CA $278 total Dec 3 - Dec 4 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/46b3f49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/d7cc9d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/b574e039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Two Bedroom house - The Galapagos Pearl Hotel Puerto Ayora 10/10 Exceptional (1) "We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura E. CA $281 CA $355 total Nov 11 - Nov 12 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information) ![3 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/a02678e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/17b173cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/f77924fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/d0327e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aventura y Confort en Galápagos – Suite Familiar Puerto Ayora 8.0/10 Very good (1) "Large property - 3 bed rooms and 3-1/2 bathrooms. It was an excellent value. The home had fantastic air conditioning - which we really appreciated after a long day of excursions. There was plenty of filtered water and the washing machine was a bonus. In terms of negatives: - No WiFi (but the host was clear about this from the beginning) - No mirrors over sinks (had to use our phone’s camera to shave) - Dogs barking at night - No hot water in the morning - No address - difficult to explain... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) York R. CA $112 CA $190 total Nov 15 - Nov 16 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Galapagos-HOLIDAY-SUITE-3-Bedrooms-6-Guests-EAST-SIDE.h90226451.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/369f220c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2ad1a614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome, 1 Bedroom, Non Smoking, City View](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2847ed9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome, 1 Bedroom, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/c9a6e134.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Galapagos Puerto Ayora 6.0/10 (1) "着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。" ![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg) アオアシカツオドリ [](https://www.expedia.ca/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25®ionId=6053670&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Island-Private-Vacation-Homes.d6053670-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Island-Private-Vacation-Homes.d6053670-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Santa Cruz Island Hotel Reviews ![Posada del Mar](//images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1_y.jpg) ### Posada del Mar 10/10 Excellent "Well maintained property, front staff was very kind and helpful, and the restaurants beside it were incredible." [](https://expedia.ca/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information) ![Hotel Fiesta](//images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f_y.jpg) ### Hotel Fiesta 10/10 Excellent "Really great staff! Very welcoming and hard working. The hotel could use a little maintenance. Beautiful landscaping." [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) ![Ikala Galapagos Hotel](//images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed_y.jpg) ### Ikala Galapagos Hotel 10/10 Excellent "Nice clean hotel" [](https://expedia.ca/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Galapagos Verde Azul](//images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/6a115ff5_y.jpg) ### Galapagos Verde Azul 10/10 Excellent "Lovely hotel set back from sea and not far to town and beach. Very helpful staff. Everything functional and fit for purpose. " [](https://expedia.ca/Puerto-Ayora-Hotels-Galapagos-Verde-Azul.h9577577.Hotel-Information) ![Acacia Galapagos Boutique Hotel](//images.trvl-media.com/lodging/92000000/91760000/91753200/91753116/8c7674f6_y.jpg) ### Acacia Galapagos Boutique Hotel 10/10 Excellent "We’ve never been treated better than we were by the staff at Hotel Acacia. Everyone was so incredibly friendly, welcoming and helpful. Special shout out to Claudia for giving us such a positive experience! The hotel has everything you need and is centrally located, plus breakfast included. " [](https://expedia.ca/Puerto-Ayora-Hotels-Acacia-Galapagos-Boutique-Hotel.h91753116.Hotel-Information) ![Fernandina Hotel & Spa Galápagos](//images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/27a5429e_y.jpg) ### Fernandina Hotel & Spa Galápagos 10/10 Excellent "I enjoyed my stay very much" [](https://expedia.ca/Puerto-Ayora-Hotels-HOTEL-FERNANDINA.h90029511.Hotel-Information) ![Capitan Max B&B](//images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg) ### Capitan Max B&B 10/10 Excellent "Lourdes and Max are very good hosts, they informed everything a guest should be aware and support a lot. " [](https://expedia.ca/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Hotel Palace Galapagos](//images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/48760e17_y.jpg) ### Hotel Palace Galapagos 10/10 Excellent "Great little family run hotel. 5 blocks from the main tourist area. Couldn't fault it! " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Palace-Galapagos.h11050675.Hotel-Information) ![Maidith Galapagos Inn](//images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/1dd0538f_y.jpg) ### Maidith Galapagos Inn 10/10 Excellent "Dennis the owner was lovely and very helpful. The bed was super comfy, the shower hot and with good pressure and the breakfast was nice and healthy. Thank you! " [](https://expedia.ca/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information) ## Find out more about Santa Cruz Island ## Santa Cruz Island Vacation Homes information | Number of reviews | | | --- | --- | | Accommodation | Vacation Homes | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Santa Fe Island](https://www.expedia.ca/5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) - [Baltra Hotels](https://www.expedia.ca/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Aparthotels in Bartolome Island](https://www.expedia.ca/Bartolome-Island-Apart-Hotels.d6336382-aaApartHotels.Travel-Guide-Accommodation) - [Lgbt Friendly Hotels in Bellavista](https://www.expedia.ca/Bellavista-Hotels-LGBT-Friendly-Hotel.0-0-d6342722-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bellavista Hotels](https://www.expedia.ca/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - 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[Visit Santa Fe Island](https://www.expedia.ca/Santa-Fe-Island.dx6336630) - [Santa Rosa Vacations](https://www.expedia.ca/Santa-Rosa.d6053725.Destination-Travel-Guides) - [Visit Santa Rosa](https://www.expedia.ca/Santa-Rosa.dx6053725) - [Tortuga Bay Beach](https://www.expedia.ca/Tortuga-Bay-Beach-Bella-Vista.d6171324.Vacation-Attraction) - [All inclusive Vacation Packages Galápagos](https://www.expedia.ca/lp/theme-vacations/all-inclusive-vacations/1371/Galapagos) - [Car rental Baltra](https://www.expedia.ca/Car-Rentals-In-Baltra.d6223000.Car-Rental-Guide) - [Car rentals near North Seymour Island](https://www.expedia.ca/Car-Rentals-In-North-Seymour-Island.d6336659.Car-Rental-Guide) - [Car rental Puerto Ayora](https://www.expedia.ca/Car-Rentals-In-Puerto-Ayora.d602686.Car-Rental-Guide) - [Car rentals near Santa Fe Island](https://www.expedia.ca/Car-Rentals-In-Santa-Fe-Island.d6336630.Car-Rental-Guide) - [Click & Rent Rental Cars in Santa Fe Island](https://www.expedia.ca/Click-Rent-Car-Rentals-In-Santa-Fe-Island.d6336630-c1089.Car-Rental-Guide-Suppliers) - [Car rentals near Galápagos](https://www.expedia.ca/Destinations-In-Galapagos.d1371.Car-Rental-Destinations) - [Enterprise Rental Cars in Santa Fe Island](https://www.expedia.ca/Enterprise-Car-Rentals-In-Santa-Fe-Island.d6336630-c15.Car-Rental-Guide-Suppliers) - [Flizzr Rental Cars in North Seymour Island](https://www.expedia.ca/Flizzr-Car-Rentals-In-North-Seymour-Island.d6336659-c1098.Car-Rental-Guide-Suppliers) - [Get Your Car Rental Cars in Santa Fe Island](https://www.expedia.ca/Get-Your-Car-Car-Rentals-In-Santa-Fe-Island.d6336630-c1120.Car-Rental-Guide-Suppliers) - [Global Rent a Car Rental Cars in Santa Fe Island](https://www.expedia.ca/Global-Rent-A-Car-Car-Rentals-In-Santa-Fe-Island.d6336630-c1062.Car-Rental-Guide-Suppliers) - [Goldcar rental Rental Cars in Santa Fe Island](https://www.expedia.ca/Goldcar-Rental-Car-Rentals-In-Santa-Fe-Island.d6336630-c1022.Car-Rental-Guide-Suppliers) - [Guerin Rental Cars in Daphne Islands](https://www.expedia.ca/Guerin-Car-Rentals-In-Daphne-Islands.d6336492-c1129.Car-Rental-Guide-Suppliers) - 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