Title: Book the Best HISTORIC Hotels in Santa Cruz Island in 2025 | Expedia.ca [Santa Cruz Island Travel Guide](https://expedia.ca/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Vacation-Rentals.d6053670.Travel-Guide-VacationRentals)[Flights to Santa Cruz Island](https://expedia.ca/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.ca/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-Island.d6053670.Car-Rental-Guide)[Santa Cruz Island Vacation Packages](https://expedia.ca/Santa-Cruz-Island.d6053670.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/04d5e478ee175ffd174b1e23d51916f4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Historic Hotels in Santa Cruz Island ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Island Historic Hotels Tonight [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-07&endDate=2025-10-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-08&endDate=2025-10-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Cruz Island Historic Hotels ![Exterior](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/e4439d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/1c80b434.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/d53c3e4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/eedc9a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lonesome George Ecolodge 2 Puerto Ayora 10/10 Exceptional (1) "Aaron and Victor were fantastic hosts! Victor even went to the store to make tea for two of our group who were ill. Staying at the Lonesome George is like living in a beautiful treehouse. Photos truly don't do it justice! We would definitely go back! " CA $139 CA $291 total Oct 9 - Oct 10 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Lonesome-George-Ecolodge-2.h66195420.Hotel-Information) ![1 bedroom, in-room safe, WiFi, bed sheets](https://images.trvl-media.com/lodging/23000000/22770000/22766200/22766145/9ea26754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player, books](https://images.trvl-media.com/lodging/23000000/22770000/22766200/22766145/e392fabb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player, books](https://images.trvl-media.com/lodging/23000000/22770000/22766200/22766145/b16c7b43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/23000000/22770000/22766200/22766145/1c1e9880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### One Bedroom With Ocean View Terrace Access. Puerto Ayora, Santa Cruz Island CA $199 CA $251 total Oct 9 - Oct 10 [](https://www.expedia.ca/Puerto-Ayora-Hotels-One-Bedroom-With-Ocean-View-Terrace-Access.h22766145.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/a362da8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/9c7526d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, in-room safe, travel crib, WiFi](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/a746834d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player, books, video library](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/e69178c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Life Two Bedroom Galapagos Casita Puerto Ayora 10/10 Exceptional (3) "We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!" CA $180 CA $229 total Oct 9 - Oct 10 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/7afe4884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bedrooms, in-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/c7f1e15e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/8c8ed24d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/d2dc07c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The lonely George Ecolodge Puerto Ayora 10/10 Exceptional (1) "We all (group of 8) LOVED this place! Super fun atmosphere and furnishings, very nice rooms, great location. Victor and Aaron were super helpful with rides for our big group and info about the area. Wish we had more time to hang out here - excellent vibe." CA $697 CA $895 total Oct 9 - Oct 10 [](https://www.expedia.ca/Puerto-Ayora-Hotels-The-Lonely-George-Ecolodge.h39884978.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23®ionId=6053670&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Cruz Island Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Santa Fe Island](https://www.expedia.ca/5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) - [Baltra Hotels](https://www.expedia.ca/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Bellavista](https://www.expedia.ca/Bellavista-Hotels-LGBT-Friendly-Hotel.0-0-d6342722-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bellavista Hotels](https://www.expedia.ca/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - [Apartments in Daphne Islands](https://www.expedia.ca/Daphne-Islands-Apartments.d6336492-aaApartments.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Galápagos](https://www.expedia.ca/Destinations-In-Galapagos-All-Inclusive-Hotel.0-0-d1371-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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