Title: Hotels by Independent in Upstate South Carolina from CA $83 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Independent in Upstate South Carolina from CA $83 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Independent Hotels ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Resort Studio with Kitchen and Two Queen | Private kitchen](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/70e13494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/01158bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson Seneca 9.0/10 Wonderful (1000) "Very beautiful place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $152 CA $189 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d57fd5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness Greenville 9.8/10 Exceptional (605) "Wonderful boutique hotel!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Ellen CA $212 CA $280 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![1 bedroom, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/464c71ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/002ffe20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/cc01b08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/88d2a0e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Greenville-Haywood Mall Greenville 9.2/10 Wonderful (188) "Great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daecia CA $180 CA $199 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/402009cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exercise/lap pool](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/86c1e212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/8de073a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/a8a1fed9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Inn and Suites Greenville 5.8/10 (153) "Good stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kendra CA $76 CA $83 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-1314-S-Pleasantburg-Dr.h95668169.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/1611bef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/b7ec145d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/020b11bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/13b6a44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Horizon Inn & Suites Anderson 4.8/10 (216) "Motel for crackheads" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan CA $74 CA $87 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/e43af84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/05d8cd44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn Clemson 9.6/10 Exceptional (945) "Amazing place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $208 CA $231 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/3e16f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/78008f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/1c4bc101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson Clemson 8.0/10 Very good (1009) "Very nice staff and great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberley CA $105 CA $117 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Reception hall](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/06863ceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/241a5cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/cb83efe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Patrick Square Clemson 9.8/10 Exceptional (767) "Beautiful hotel and close to restaurants and bars. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) susan CA $208 CA $231 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/cbe6a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e408dd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson Clemson 9.6/10 Exceptional (548) "Great place for visiting the university " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Guy CA $180 CA $200 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/cba17315.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/48d7212d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/eb4c59a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/546c8477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swamp Rabbit Inn Greenville Downtown 9.0/10 Wonderful (351) "Rooms were very clean and had everything I needed. Keypad access was cool and came in handy! Only stayed overnight but would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sophie CA $162 CA $193 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Greenville-Hotels-Swamp-Rabbit-Inn.h10240653.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07®ionId=553248635975748552&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Independent.0-0-d553248635975748552--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Independent.0-0-d553248635975748552--bIndependent.Travel-Guide-Filter-Hotels) ## Top Upstate South Carolina Hotel Reviews ![Comfort Suites Greenville Airport](//images.trvl-media.com/lodging/47000000/46120000/46116400/46116309/9d9a99c3_y.jpg) ### Comfort Suites Greenville Airport 10/10 Excellent "Great stay! Clean rooms, very nice and quiet. We were on the top floor and a few planes flying over were loud in the evening and late morning, but it lasted only a few seconds and there were minimal planes. Would stay here again for sure! (Love having a sofa to sit on!)" [](https://expedia.ca/Greenville-Spartanburg-Hotels-Comfort-Suites.h46116309.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "kickback - clean - convenient - safe" [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Wingate by Wyndham - Greenville-Airport](//images.trvl-media.com/lodging/1000000/50000/43500/43464/a55a98c9_y.jpg) ### Wingate by Wyndham - Greenville-Airport 10/10 Excellent "Very clean very quiet nice staff " [](https://expedia.ca/Greenville-Hotels-Wingate-By-Wyndham-Greenville-Airport.h43464.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "I feel safe. " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Everything was awesome." [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Comfort Inn Greenville - Haywood Mall](//images.trvl-media.com/lodging/1000000/30000/25000/24994/6e5638cc_y.jpg) ### Comfort Inn Greenville - Haywood Mall 10/10 Excellent "Good condition. Nice room. Good breakfast. Nice lobby. Descent gym." [](https://expedia.ca/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Clean rooms, friendly staff, no room service contact, no TV internet, comfortable bed, nice big bathroom. I wish room service would answer their phone." [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Urban Boutique Hotel, BW Signature Collection](//images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b_y.jpg) ### Urban Boutique Hotel, BW Signature Collection 10/10 Excellent "Location and affordability describe this hotel best. Located within a 5 minute drive to downtown Greenville makes this a great place to stay. Great rate makes it the hotel to choose. It was clean and had a nice breakfast. The only con for me was that the mattress was like a marshmallow. I did sleep well though. I will return here when visiting Greenville again." [](https://expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Was ok,I could come back again" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Anglewood Hotels](https://www.expedia.ca/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Motel 6 Hotels in Brookhaven](https://www.expedia.ca/Brookhaven-Hotels-Motel-6.0-0-d553248635975852330--bMotel6.Travel-Guide-Filter-Hotels) - [Starwood Capital Hotels in Central](https://www.expedia.ca/Central-Hotels-Starwood-Capital.0-0-d10503--bStarwoodCapital.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Clover](https://www.expedia.ca/Clover-Hotels-Motel-6.0-0-d3000455892--bMotel6.Travel-Guide-Filter-Hotels) - 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[Drury Inn & Suites Hotels in Upstate South Carolina](https://www.expedia.ca/Upstate-South-Carolina-Hotels-Drury-Inn-Suites.0-0-d6057939--bDruryInnSuites.Travel-Guide-Filter-Hotels) - [Extended Stay America Hotels in Upstate South Carolina](https://www.expedia.ca/Upstate-South-Carolina-Hotels-Extended-Stay-America.0-0-d6057939--bExtendedStayAmerica.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Upstate South Carolina](https://www.expedia.ca/Upstate-South-Carolina-Hotels-La-Quinta-Inn-Suites.0-0-d6057939--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Welcome](https://www.expedia.ca/Welcome-Hotels-Marriott-Hotels-Resorts.0-0-d3000353249--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [B&B in Woodruff](https://www.expedia.ca/Woodruff-Bed-And-Breakfast.d6348219-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Woodruff](https://www.expedia.ca/Woodruff-Hotels-Cheap-Hotels.0-0-d6348219-tCheapHotels.Travel-Guide-Filter-Hotels) - 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[Flights from Vancouver (YVR) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/yvr/spa/vancouver-to-spartanburg) - [Flights from Toronto (YYZ) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/yyz/spa/toronto-to-spartanburg) - [Visit Anglewood](https://www.expedia.ca/Anglewood.dx553248635975857985) - [Central Vacations](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides) - [Rental cars Spartanburg Downtown Memorial airport](https://www.expedia.ca/Car-Rentals-In-Spartanburg-Downtown-Memorial.d6032031.Car-Rental-Guide) - [Book Independent in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Independent.0-0-d553248635975748552--bIndependent.Travel-Guide-Filter-Hotels)