Title: Book the Best PET FRIENDLY Hotels in Upstate South Carolina, SC - Upstate South Carolina Dog-Friendly Hotels | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina # Find Pet-friendly Hotels in Upstate South Carolina, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Pet-friendly Hotels Tonight [Nov 16 - Nov 17](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-11-16&endDate=2025-11-17&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 17 - Nov 18](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-11-17&endDate=2025-11-18&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-11-21&endDate=2025-11-23&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-11-28&endDate=2025-11-30&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Pet-friendly Hotels ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Resort Studio with Kitchen and Two Queen | Private kitchen](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/70e13494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson Seneca 9.0/10 Wonderful (1001) "Overall great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $153 CA $190 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/fbbe5f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/c08a69bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/56ecee45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d45e119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Greer Greenville, SC Greer 9.6/10 Exceptional (401) "Nice hotel, convenient location with helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $195 CA $212 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/ac7a917f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/2bb8d81a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson Seneca 9.2/10 Wonderful (781) "Very friendly and clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $134 CA $147 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/afac9f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/dfd5de25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/6b7207b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/7f3f162b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Greenville Airport Greenville 8.2/10 Very good (283) "Clean room, friendly staff, I would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $107 CA $118 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/573947b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/c05bf676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/1ebed4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Gaffney Gaffney 8.6/10 Excellent (660) "Clean room, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gary CA $122 CA $133 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) ![Standard Cabin, Courtyard View](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/344b1497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/ddc562e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Cabin, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/5acfec99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 King Bed with Sofa bed, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/7f4f7187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carolina Camp Cedar Pickens CA $135 CA $266 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/347fe1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/3c50d204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 Downtown 8.0/10 Very good (659) "Ok hotel for a quick stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $106 CA $125 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/441edd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/f49d90aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7bc9a82a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson Anderson 7.8/10 Good (1004) "Wonderful for families—safe, quiet, and the staff made us feel at home." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $88 CA $98 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/83fe6802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/c63efdfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/9ba3afd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/94af1b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gnome Hill Cottage - A Rustic Pet-Friendly Cottage In The Woods Cleveland 9.8/10 Exceptional (107) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $154 CA $202 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/14e3230b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/94f8bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/706f626f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson Anderson 8.2/10 Very good (1002) "Room was clean, staff was nice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martina CA $112 CA $124 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-30&endDate=2025-12-01®ionId=553248635975748552&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ### Quality Inn Seneca Clemson Area US-123 10/10 Excellent "Clean room w fridge and microwave Comfy bed" [](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ### Hyatt Place Greenville/Haywood 10/10 Excellent "The cookie was delicious. The room is compact but comfortable." [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ### Drury Inn & Suites Greenville 10/10 Excellent "Everything was exceptional. Money well spent. " [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "." [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ### Hyatt Regency Greenville 10/10 Excellent "Convenient to Main Street area. " [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Motel 6 Greenville, SC](//images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/af5363f6_y.jpg) ### Motel 6 Greenville, SC 10/10 Excellent "I had never stayed here before but the rates were much better than all the others so I was kind of skeptical at first. But upon arriving and checking the room out, I was pleasantly pleased. It comes with a small kitchen area which most do not, especially for the price. I would definitely stay here again and would recommend it to others. The staff are very nice and helpful and that’s a rarity as well. My wife keeps a log on the good, bad and ugly of the rooms we stay in for a future reference and this will most assuredly go into the good list. " [](https://expedia.ca/Greenville-Hotels-Motel-6-Greenville.h1107497.Hotel-Information) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Q" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Anglewood Hotels](https://www.expedia.ca/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Hotels with a Pool in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - [Hotels with Free Airport Shuttle in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Airport-Shuttle.0-0-d242-tHotelswithFreeAirportShuttle.Hotel-Filter-Destinations) - 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