Title: Upstate South Carolina Guest Houses from CA $276 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in Upstate South Carolina from CA $276 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-10&endDate=2025-10-12&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Upstate South Carolina Guest Houses ![Exterior](https://images.trvl-media.com/lodging/72000000/71520000/71510200/71510120/w904h683x60y0-22569256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71520000/71510200/71510120/3a7b914c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/72000000/71520000/71510200/71510120/w907h683x58y0-5f3a14ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/72000000/71520000/71510200/71510120/72255b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more. Travelers Rest 10/10 Exceptional (73) "Very nice and great location" [](https://www.expedia.ca/Travelers-Rest-Hotels-Steps-From-The-Swamp-Rabbit-Trail.h71510120.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/30000000/29490000/29483500/29483484/1672b9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels](https://images.trvl-media.com/lodging/30000000/29490000/29483500/29483484/9f758c3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/30000000/29490000/29483500/29483484/abc7b4b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/30000000/29490000/29483500/29483484/d903a2fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Suite in Downtown Simpsonville Simpsonville 10/10 Exceptional (61) "We stayed here two nights for a concert at CCNB. We were conveniently located to the venue and were able to easily walk to downtown shops and restaurants. The apartment itself was cute, comfortable, and had everything we needed to enjoy our stay. " CA $118 CA $276 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Simpsonville-Hotels-Private-Suite-In-Downtown-Simpsonville.h29483484.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34940000/34930400/34930317/d06fb361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34940000/34930400/34930317/a162ba57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34940000/34930400/34930317/83768189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/35000000/34940000/34930400/34930317/69c8b751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chauga River - The Guest House - Private - Secluded Mountain Rest 10/10 Exceptional (91) "The house was very clean and had everything we " [](https://www.expedia.ca/Mountain-Rest-Hotels-Chauga-River-The-Guest-House-Private-Secluded.h34930317.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37620000/37615100/37615096/90-c905c55e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37620000/37615100/37615096/e5728e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/38000000/37620000/37615100/37615096/7211ac0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/38000000/37620000/37615100/37615096/f4f71fd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Light and airy contemporary guest house with private deck and parking. Travelers Rest 10/10 Exceptional (34) "This is an excellent place to stay. Accommodation were great, area was very quiet and the hosts were very inviting. Thank you Bob and Barbara for a truly lovely experience. " [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Light-And-Airy-Contemporary-Guest-House-With-Private-Deck-And-Parking.h37615096.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/59000000/58800000/58791300/58791251/fd4a83f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/59000000/58800000/58791300/58791251/52e7aeea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, table tennis](https://images.trvl-media.com/lodging/59000000/58800000/58791300/58791251/985750bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/59000000/58800000/58791300/58791251/bde1c4e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful Lakefront Getaway Close to Clemson Townville 10/10 Exceptional (41) "Great place to stay when visiting Clemson! Nice house and lake property. " [](https://www.expedia.ca/Townville-Hotels-Peaceful-Lakefront-Getaway-Close-To-Clemson.h58791251.Hotel-Information) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/24000000/23280000/23280000/23279966/4595f7a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/24000000/23280000/23280000/23279966/63c9589c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/24000000/23280000/23280000/23279966/fb84bb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table tennis, books](https://images.trvl-media.com/lodging/24000000/23280000/23280000/23279966/f234bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville. Chesnee 9.2/10 Wonderful (20) "The host of this property were overly accommodating! Property was as described and very comfortable!" [](https://www.expedia.ca/Chesnee-Hotels-Bright-And-Beautiful-Cottage-Near-Spartanburg.h23279966.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-14&endDate=2025-10-15®ionId=553248635975748552&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Guest-Houses.d553248635975748552-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Guest-Houses.d553248635975748552-aaGuestHouses.Travel-Guide-Accommodation) ## Top Upstate South Carolina Hotel Reviews ![Hampton Inn & Suites Greenville Airport, SC](//images.trvl-media.com/lodging/12000000/11920000/11919200/11919192/de1bb5e2_y.jpg) ### Hampton Inn & Suites Greenville Airport, SC 10/10 Excellent "Check in was quick and easy, and the entire place was clean and tidy. The bed was very comfortable." [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Airport.h11919192.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Very Clean and staff was very polite." [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Comfort Suites Greenville Airport](//images.trvl-media.com/lodging/47000000/46120000/46116400/46116309/9d9a99c3_y.jpg) ### Comfort Suites Greenville Airport 10/10 Excellent "Clean comfortable room" [](https://expedia.ca/Greenville-Spartanburg-Hotels-Comfort-Suites.h46116309.Hotel-Information) ![Woodspring Suites Greenville Airport](//images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/69b6f44b_y.jpg) ### Woodspring Suites Greenville Airport 10/10 Excellent "Great location and very secure property" [](https://expedia.ca/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](//images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Everything! Beautiful, convenient and wonderful staff!" [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Nice easy walk to bon seCour center" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Great VALUE and great room. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Highly recommended Really good value for money " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Golf Clean rooms Staff was awesome Beautiful property " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ## Find out more about Upstate South Carolina ## Upstate South Carolina Guest Houses information | Number of reviews | 318 | | --- | --- | | Accommodation | 6 Guest Houses | | Lowest Price | CA $276 | | Highest Price | CA $276 | ## Explore a world of travel with Expedia - 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[Flights from Elmira (ELM) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/elm/spa/elmira-to-spartanburg) - [Flights from Fayetteville (FAY) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/fay/spa/fayetteville-to-spartanburg) - [Flights from Frederick (FDK) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/fdk/spa/frederick-to-spartanburg) - [Flights from Greenville (GSP) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/gsp/spa/greenville-to-spartanburg) - [Flights from New Haven (HVN) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/hvn/spa/new-haven-to-spartanburg) - [Flights from Niagara Falls (IAG) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/iag/spa/niagara-falls-to-spartanburg) - [Flights from Kinston (ISO) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/iso/spa/kinston-to-spartanburg) - [Flights from Manville (JVI) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/jvi/spa/manville-to-spartanburg) - [Flights from Macon (MCN) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/mcn/spa/macon-to-spartanburg) - 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