Title: Book the Best Greenville - Spartanburg SPA Resorts - Spa Hotels in Greenville - Spartanburg, SC | Expedia.ca [Greenville - Spartanburg Travel Guide](https://expedia.ca/Greenville-Spartanburg.dx6035267)[Hotels in Greenville - Spartanburg](https://expedia.ca/Greenville-Spartanburg-Hotels.d6035267.Travel-Guide-Hotels)[Vacation Rentals in Greenville - Spartanburg](https://expedia.ca/Greenville-Spartanburg-Vacation-Rentals.d6035267.Travel-Guide-VacationRentals)[Flights to Greenville - Spartanburg](https://expedia.ca/Cheap-Flights-To-Greenville-Spartanburg.d6035267.Travel-Guide-Flights)[Things to do in Greenville - Spartanburg](https://expedia.ca/Things-To-Do-In-Greenville-Spartanburg.d6035267.Travel-Guide-Activities)[Greenville - Spartanburg Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville-Spartanburg.d6035267.Car-Rental-Guide)[Greenville - Spartanburg Vacation Packages](https://expedia.ca/Greenville-Spartanburg.d6035267.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Greenville - Spartanburg, SC ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville - Spartanburg Spa Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2025-10-15&endDate=2025-10-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2025-10-16&endDate=2025-10-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Greenville - Spartanburg Spa Hotels ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/0671c5e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/924dd6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown 9.6/10 Exceptional (392) "Very expensive but great location. " CA $406 CA $459 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/aa0a358b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/6b940d91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d57fd5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness Greenville 9.8/10 Exceptional (601) "Wonderful boutique hotel!!" CA $225 CA $295 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/24c29149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique Travelers Rest 9.6/10 Exceptional (30) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." CA $616 CA $678 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/0fc978a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/ae95b708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Room, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/2f186f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Cabin, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/ed481a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SKYLARANNA Resort & Spa Hendersonville 8.2/10 Very good (325) "Quiet, close to I-26, and nice outdoor restaurant on premises with good food. " CA $171 CA $233 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Asheville-Hotels-Skylaranna-Hotel-And-Resort.h54524318.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/1dc0c9a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![French Country Room](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/f665c6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/d5dd3f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/7ceab56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Echo Mountain Inn Hendersonville 9.0/10 Wonderful (538) "We loved our stay! A truly special place!!" CA $160 CA $180 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Asheville-Hotels-Echo-Mountain-Inn.h13209511.Hotel-Information) ![1 treatment room, massages](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/7f348ae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/5f74fd6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/f1c0642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/e166e20f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1898 Waverly Inn Hendersonville 9.4/10 Exceptional (285) "You can't go wrong staying here. The staff are exceptional and the breakfast is amazing. Great Place, easy walk to downtown." CA $239 CA $270 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Asheville-Hotels-1898-Waverly-Inn.h898978.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/8063695a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Bedrooms (The Lady Anne Room)](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/a490469b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/b49fc2c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/764f9317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Morgan and Wells B&B Shelby 9.6/10 Exceptional (88) "Always excellent to stay at M and W!!" CA $207 CA $234 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Shelby-Hotels-Morgan-And-Wells-BB.h11043190.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/70dd5eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/ca7d3507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/ceeaab49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/07befbdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greystone Inn Lake Toxaway 9.4/10 Exceptional (85) "Most beautiful quiet and peaceful old guest home. " CA $420 CA $516 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/54000000/53020000/53018100/53018097/85a607f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/54000000/53020000/53018100/53018097/4721de4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/54000000/53020000/53018100/53018097/cad0d475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/54000000/53020000/53018100/53018097/ef421c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Horse Shoe Farm Hendersonville 9.6/10 Exceptional (7) "Beautiful buildings and surrounding farm land. The dinner was exceptional and I highly recommend it. Loved the fire pit in the evenings with s’mores and wine. " CA $559 CA $631 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Asheville-Hotels-The-Horse-Shoe-Farm.h53018097.Hotel-Information) ![Couples treatment rooms, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/b51de8d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 King Bed (First Floor)](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/de3a66af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 King Bed, Non Smoking (Baby's Bungalow)](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/5584c3e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/9fc2aad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Lure Inn and Spa Lake Lure 8.2/10 Very good (61) "Love this place - beautiful furnishings and art" CA $189 CA $213 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Lake-Lure-Hotels-Lake-Lure-Inn-And-Spa.h107204500.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30®ionId=6035267&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Greenville - Spartanburg Hotel Reviews ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "The staff were very friendly. I checked out and left my phone in the room and they allowed me to go back in the room, no hassle at all to retrieve my phone!!" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Clean rooms" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Stayed for a quick stop but everything was good " [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Everything is super nice and clean" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ## Explore a world of travel with Expedia - 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