Title: Book the Best Greenville WINERY Hotels in 2025 | Expedia.ca [Greenville Travel Guide](https://expedia.ca/Greenville.dx1388)[Hotels in Greenville](https://expedia.ca/Greenville-Hotels.d1388.Travel-Guide-Hotels)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d1388.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d1388.Travel-Guide-Flights)[Things to do in Greenville](https://expedia.ca/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities)[Greenville Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide)[Greenville Vacation Packages](https://expedia.ca/Greenville.d1388.Destination-Travel-Guides) ![Greenville which includes a marina, general coastal views and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63749-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Winery Hotels in Greenville, SC ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville Winery Hotels Tonight [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-09-24&endDate=2025-09-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Greenville Winery Hotels ## Top Greenville Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels near Bon Secours Wellness Arena](https://www.expedia.ca/Bon-Secours-Wellness-Arena-Hotels.0-l6082715-0.Travel-Guide-Filter-Hotels) - [Hotels near Centre Stage](https://www.expedia.ca/Centre-Stage-Hotels.0-l553248621532656774-0.Travel-Guide-Filter-Hotels) - 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