Title: Top Hotels in Antofagasta de la Sierra Department | Expedia.ca [Vacation Rentals in Antofagasta de la Sierra Department](https://expedia.ca/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Vacation-Rental-Destinations)[Antofagasta de la Sierra Department Car Rentals](https://expedia.ca/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Car-Rental-Destinations)[Antofagasta de la Sierra Department Vacations](https://expedia.ca/Antofagasta-De-La-Sierra-Department.d553248635975749483.Destination-Travel-Guides) ![This area is of an incredible diversity, it is part of the Argentine Puna. #roadtrip](https://images.trvl-media.com/place/6348231/b8d035fc-a159-4a83-8987-4fe3b3c3e54e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Graciela Arena # Search Antofagasta de la Sierra Department Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Antofagasta de la Sierra Department ![](https://mediaim.expedia.com/destination/2/bdaecc5a35289f7a555ef5e216022814.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Antofagasta de la Sierra [](https://expedia.ca/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Nov 7 - Nov 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2025-11-07&endDate=2025-11-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 8 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2025-11-08&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels in Antofagasta de la Sierra Department ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations) ## Top Antofagasta de la Sierra Department Hotel Reviews ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Antofagasta de la Sierra Department - [Antofagasta de la Sierra Hotels](https://expedia.ca/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) ### Explore more hotels - [Hosteria Pucara](https://expedia.ca/Antofagasta-De-La-Sierra-Hotels-Hosteria-Pucara.h42527742.Hotel-Information) [See a list of all hotels in Antofagasta de la Sierra Department](https://expedia.ca/All-Antofagasta-De-La-Sierra-Department-Hotels.d553248635975749483.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Antofagasta de la Sierra Department on Expedia.com.ar](https://www.expedia.com.ar/Destinos-En-Departamento-Antofagasta-De-La-Sierra.d553248635975749483.Destinos-con-Hoteles) ### Expedia's Latest Trends Hotels - [Hilton Mississauga/Meadowvale](https://expedia.ca/Toronto-Hotels-Hilton-MississaugaMeadowvale.h27992.Hotel-Information) - [Tokatoka Resort Hotel](https://expedia.ca/Nadi-Hotels-Tokatoka-Resort-Hotel.h5194650.Hotel-Information) - 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[Beach Hotel in Slovenia](https://expedia.ca/Destinations-In-Slovenia-Beach-Hotel.0-0-d11413-tBeachHotel.Hotel-Filter-Destinations) - [Holiday Inn Express Hotel & Suites Jasper by IHG](https://expedia.ca/Jasper-Hotels-Holiday-Inn-Express-Hotel-Suites-Jasper.h1802413.Hotel-Information) Flights - [Flights from Kingston (KIN) to Vancouver (YVR)](https://expedia.ca/lp/flights/kin/yvr/kingston-to-vancouver) - [Flights from Velika Gorica (ZAG) to Sarajevo (SJJ)](https://expedia.ca/lp/flights/zag/sjj/zagreb-to-sarajevo) - [Flights from Paris (CDG) to Edinburgh (EDI)](https://expedia.ca/lp/flights/cdg/edi/paris-to-edinburgh) - [Flights from Toronto](https://expedia.ca/lp/flights/178314/flights-from-toronto) - [WestJet Edmonton (YEG) to Toronto (YYZ) flights](https://expedia.ca/lp/flight-routes/westjet-from-edmonton-intl-to-pearson-intl/ws/yeg/yyz) - [Flights from Vancouver (YVR) to Sidney (YYJ)](https://expedia.ca/lp/flights/yvr/yyj/vancouver-to-victoria) - [Flights from Edmonton (YEG) to Cancun (CUN)](https://expedia.ca/lp/flights/yeg/cun/edmonton-to-cancun) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)