Title: 10 Best South America Boutique Hotels for 2025 | Expedia.ca [South America Travel Guide](https://expedia.ca/South-America.dx6023117)[South America Hotels](https://expedia.ca/Destinations-In-South-America.d6023117.Hotel-Destinations)[Vacation Rentals in South America](https://expedia.ca/Destinations-In-South-America.d6023117.Vacation-Rental-Destinations)[South America Flights](https://expedia.ca/Destinations-In-South-America.d6023117.Flight-Destinations)[South America Car Rentals](https://expedia.ca/Destinations-In-South-America.d6023117.Car-Rental-Destinations)[South America Vacations](https://expedia.ca/South-America.d6023117.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/66000/66593-Cusco.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Boutique Hotels in South America - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South America Boutique Hotels Tonight [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=6023117&startDate=2025-11-03&endDate=2025-11-04&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6023117&startDate=2025-11-04&endDate=2025-11-05&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6023117&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6023117&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South America Boutique Hotels ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/42cccf50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/d87df7fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/1521a835.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/2c78686b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mine Hotel Boutique Palermo 9.6/10 Exceptional (1002) "Such a beautiful spot in the heart of Palermo Soho! Whether you on solo or traveling with your partner, I recommend this charming oasis. The staff kind and attentive, with many recommendations. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sophia CA $274 CA $278 total Nov 23 - Nov 24 [](https://www.expedia.ca/Buenos-Aires-Hotels-Mine-Hotel-Boutique.h1794972.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/8c9c0b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/e990435d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Room, Jetted Tub | Private spa tub](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/2d157c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/23fcac1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aubrey Hotel Boutique Bellavista 9.4/10 Exceptional (132) "Property was closed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $183 CA $183 total Dec 2 - Dec 3 [](https://www.expedia.ca/Santiago-Hotels-The-Aubrey-Santiago.h3657439.Hotel-Information) ![Suite, Terrace | Terrace/patio](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/b00c3792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/75b0bdd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Argentinean cuisine, garden views ](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/fa7014ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/08a8f165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fierro Hotel Buenos Aires Palermo 9.8/10 Exceptional (1003) "Very friendly and helpful staff, good breakfast, spacious room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sophia CA $332 CA $336 total Nov 4 - Nov 5 [](https://www.expedia.ca/Buenos-Aires-Hotels-Fierro-Hotel-Buenos-Aires.h3883785.Hotel-Information) ![Bicycling](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/9a92c93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/4786393a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 8 per person)](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/c63d0c04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/af5c001a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CasaCalma Hotel El Centro 9.6/10 Exceptional (972) "We enjoyed our time at this great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane CA $140 CA $145 total Nov 4 - Nov 5 [](https://www.expedia.ca/Buenos-Aires-Hotels-CasaCalma-Hotel.h2553557.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/43268e19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/013a36c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/981aee79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/08afcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vain Boutique Hotel Palermo 9.2/10 Wonderful (651) "Good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $191 CA $195 total Nov 25 - Nov 26 [](https://www.expedia.ca/Buenos-Aires-Hotels-Vain-Boutique-Hotel.h1808145.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/2ed2aa61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/238bca89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/91a110e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/98206176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ananda Hotel Boutique Cartagena Walled City 9.2/10 Wonderful (422) "good staff" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Yuanlong CA $361 CA $361 total Nov 5 - Nov 6 [](https://www.expedia.ca/Cartagena-Hotels-Ananda-Hotel-Boutique.h2645670.Hotel-Information) ![Junior Suite](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/ee86340b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/f232d9bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/fcc61d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/d714243c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stannum Boutique Hotel & Spa Downtown La Paz 9.4/10 Exceptional (721) "Good breakfast. The room was quiet. Cleaning was done fairly quickly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iaroslav CA $160 CA $160 total Nov 23 - Nov 24 [](https://www.expedia.ca/La-Paz-Hotels-Stannum-Boutique-Hotel-Spa.h5714062.Hotel-Information) ![Indoor spa tub](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/99e3e69b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, Turkish bath, body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/38e0d9f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Azur](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/dc285559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/7cbdffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Azur Real Hotel Boutique & Spa Centro 9.4/10 Exceptional (365) "Nice hotel, staff very friendly and nice food. Pay in cash if possible as cheaper than using a card. Good ac system and very tasty granola " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Lucas [](https://www.expedia.ca/Cordoba-Hotels-Azur-Real-Hotel-Boutique.h2803575.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/962f0e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room | Courtyard view](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/6a7389c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/9b7f02ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/b204e6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duque Hotel Boutique & Spa Palermo 9.4/10 Exceptional (846) "Excellent staff, comfortable room, great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean CA $241 CA $245 total Dec 2 - Dec 3 [](https://www.expedia.ca/Buenos-Aires-Hotels-Duque-Hotel-Boutique-Spa.h3439490.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/1c390246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Balcony](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/a5f07a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/2b045cdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/4c619204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SU Merced Boutique Hotel Downtown Santiago 9.2/10 Wonderful (224) "Staff was excellent. Breakfast buffet was great. Rooms were comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/Santiago-Hotels-SU-Merced-Boutique-Hotel.h5441563.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18®ionId=6023117&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Boutique-Hotel.0-0-d6023117-tBoutiqueHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Boutique-Hotel.0-0-d6023117-tBoutiqueHotel.Hotel-Filter-Destinations) ## Top South America Hotel Reviews ![Hilton Buenos Aires](//images.trvl-media.com/lodging/1000000/550000/547000/546934/d51890e8_y.jpg) ### Hilton Buenos Aires 10/10 Excellent "Great area to walk!" [](https://expedia.ca/Buenos-Aires-Hotels-Hilton-Buenos-Aires.h546934.Hotel-Information) ![NH Buenos Aires Tango](//images.trvl-media.com/lodging/4000000/3310000/3307900/3307803/4c66c3b9_y.jpg) ### NH Buenos Aires Tango 10/10 Excellent "I suggest providing Kleenex will be good in the bathroom and need to provide cumple trash cans in bedroom. That will be great." [](https://expedia.ca/Buenos-Aires-Hotels-NH-Buenos-Aires-Tango.h3307803.Hotel-Information) ![Mercure Santiago Centro](//images.trvl-media.com/lodging/2000000/1550000/1541200/1541172/0a5f7e42_y.jpg) ### Mercure Santiago Centro 10/10 Excellent "Very central location. Most city landmarks at walking distance. Friendly staff." [](https://expedia.ca/Santiago-Hotels-Mercure-Santiago-Centro.h1541172.Hotel-Information) ![Lennox Hotel Buenos Aires](//images.trvl-media.com/lodging/5000000/4190000/4182700/4182634/ffb5b7b3_y.jpg) ### Lennox Hotel Buenos Aires 10/10 Excellent "⭐️⭐️⭐️⭐️⭐️ Very convenient hotel, perfectly located in the downtown area! Everything was clean, the service was excellent, and the staff was friendly and helpful. I really enjoyed my stay and would definitely come back." [](https://expedia.ca/Buenos-Aires-Hotels-Lennox-Hotel-Buenos-Aires.h4182634.Hotel-Information) ![Libertador Hotel](//images.trvl-media.com/lodging/1000000/10000/9300/9291/d48bbed6_y.jpg) ### Libertador Hotel 10/10 Excellent "Stay was perfect!!" [](https://expedia.ca/Buenos-Aires-Hotels-Libertador-Hotel.h9291.Hotel-Information) ![Melia Paulista](//images.trvl-media.com/lodging/2000000/1070000/1062900/1062869/2882d35d_y.jpg) ### Melia Paulista 10/10 Excellent "Staff is amazing, especially Rebecca at the front. Very good location on Paulista. The kids play area was a huge hit with our 2yo son. Highly recommend this hotel for families with young kids, and others." [](https://expedia.ca/Sao-Paulo-Hotels-Melia-Paulista.h1062869.Hotel-Information) ![InterContinental São Paulo by IHG](//images.trvl-media.com/lodging/1000000/200000/198400/198375/242e7b38_y.jpg) ### InterContinental São Paulo by IHG 10/10 Excellent "Fantastic and helpful staff. Room service staff was fantastic. Marcello and his colleagues at the bar were great snd front desk staff are fantastic. " [](https://expedia.ca/Sao-Paulo-Hotels-InterContinental-Sao-Paulo.h198375.Hotel-Information) ![Almacruz Hotel y Centro de Convenciones](//images.trvl-media.com/lodging/1000000/10000/1500/1496/b4c00de4_y.jpg) ### Almacruz Hotel y Centro de Convenciones 10/10 Excellent "It is a beautiful place,excellent services,very pleasant workers and the location was great" [](https://expedia.ca/Santiago-Hotels-Almacruz-Hotel-Y-Centro-De-Convenciones.h1496.Hotel-Information) ![Regal Pacific Buenos Aires](//images.trvl-media.com/lodging/2000000/1250000/1246600/1246568/a11bbed3_y.jpg) ### Regal Pacific Buenos Aires 10/10 Excellent "Clean room and great service " [](https://expedia.ca/Buenos-Aires-Hotels-Regal-Pacific-Buenos-Aires.h1246568.Hotel-Information)