Title: Book The Best Hotels in Defiance, MO for 2025 from CA $96 - Fully Refundable Options - Expedia.ca

  

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Photo by Michael True

# Find hotels in Defiance, MO from CA $96

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## Go beyond your typical stay in Defiance

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&amenities=PETS)

Chalet

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&lodging=CHALET)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&travelerType=family_friendly)

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&lodging=APART_HOTEL)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&lodging=COTTAGE)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&lodging=CABIN)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&lodging=CONDO)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&amenities=WATER_PARK)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&lodging=APARTMENT)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&amenities=HOT_TUB)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-11-03&d1=2025-11-03&endDate=2025-11-05&d2=2025-11-05&amenities=POOL)

## Check prices for these dates

Tonight

[Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-10-20&endDate=2025-10-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 21 - Oct 22](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-10-21&endDate=2025-10-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Compare 847 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/446bd1a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/cb7cc1f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/c85b5876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

8.2/10

Very good

(1035)

"Clean room and staff was great "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beth

CA $119

CA $138 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information)

![Ballroom](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/66ab3de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/1893bab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/9fbd251c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Wildwood Hotel

Wildwood

9.2/10

Wonderful

(1601)

"Perfect stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Justin

CA $124

CA $150 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/422/a42ce99e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/500/422/b3fcce87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/500/422/d1343ecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/500/422/w2883h1805x9y0-d898bd46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sonesta ES Suites St. Louis - Chesterfield

Chesterfield

8.0/10

Very good

(1011)

"Clean room,Friendly staff, Good location and Good Breakfast options"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Micheal

CA $122

CA $141 total

includes taxes & fees

Oct 29 - Oct 30

[](https://www.expedia.ca/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/860000/856300/856255/82e85f2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/856300/856255/a1e7f680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/856300/856255/fc6ffded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/856300/856255/306e761a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Eureka/Six Flags Nearby

Eureka

7.0/10

Good

(1012)

"Clean rooms fully stocked room with towels "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $85

CA $99 total

includes taxes & fees

Nov 3 - Nov 4

[](https://www.expedia.ca/St-Louis-Hotels-Super-8-By-Wyndham-EurekaSix-Flags-Nearby.h856255.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/9fa9b759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/0abab300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/5bb121ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/f5ac4f27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Warrenton

Warrenton

7.4/10

Good

(1007)

"Very friendly staff. Nice place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bobby

CA $120

CA $138 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Warrenton-Hotels-Baymont-By-Wyndham-Warrenton.h124484.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/00255b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/7256ef67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/4e2b8726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/b2be25f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus St. Louis West-Westport

Maryland Heights

8.0/10

Very good

(1019)

"It was a very nice place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jill

CA $121

CA $140 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/d38dcff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/660bdaf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/ac681623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/54ff18c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Wentzville St Louis West by IHG

Wentzville

9.4/10

Exceptional

(810)

"Room and bathroom were very clean. Plenty of parking. And the breakfast was wonderful, plenty of options to choose from."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bryce

CA $189

CA $226 total

includes taxes & fees

Nov 1 - Nov 2

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-Suites-Wentzville-St-Louis-West.h35848753.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1220000/1216300/1216259/9e4f56d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1220000/1216300/1216259/5d4de429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1220000/1216300/1216259/5003d042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1216300/1216259/163dc30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham St Peters/St Charles

St. Peters

6.4/10

(999)

"The carpet felt a little damp but aside from that the room was clean and comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nikki

CA $92

CA $105 total

includes taxes & fees

Oct 22 - Oct 23

[](https://www.expedia.ca/St-Louis-Hotels-Days-Inn-By-Wyndham-St-PetersSt-Charles.h1216259.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/133d5cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/28e7b062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/9fba35aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/08db7b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn & Suites O'Fallon MO - Technology Drive

O'Fallon

8.8/10

Excellent

(1016)

"Great hotel! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffrey Frank

CA $122

CA $144 total

includes taxes & fees

Oct 27 - Oct 28

[](https://www.expedia.ca/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rodeo Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/b33425c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/76ca3207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/cb1b5cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hollywood Casino & Hotel St. Louis

Maryland Heights

8.4/10

Very good

(2177)

"Always our favorite place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Julie

CA $131

CA $173 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information)

![1 bedroom, Egyptian cotton sheets, premium bedding, pillowtop beds](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/23b516cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/d2118181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/f94e668c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/3a1e3bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Washington Hotel

Washington

9.0/10

Wonderful

(612)

"Would stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alisa

CA $181

CA $206 total

includes taxes & fees

Oct 22 - Oct 23

[](https://www.expedia.ca/Washington-Hotels-Best-Western-Plus-Washington-Hotel.h1077183.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/cca92dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/e138a86a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/w2901h1303x0y3-988798bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/a6dd6a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel by Marriott St. Louis Chesterfield

Chesterfield

9.2/10

Wonderful

(211)

"Friendly staff, nice shower, good coffee"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bryan

CA $213

CA $247 total

includes taxes & fees

Oct 30 - Oct 31

[](https://www.expedia.ca/St-Louis-Hotels-AC-Hotel-By-Marriott-St-Louis-Chesterfield.h73099889.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/8c366380.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/bdc9d482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/a9e25e16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/3b030eed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Charles St. Peters

St. Charles

8.0/10

Very good

(1018)

"Excellent hotel. Excellent location, friendly staff, and delicious breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jean ss

CA $126

CA $145 total

includes taxes & fees

Nov 18 - Nov 19

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25500/25401/c540792a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25500/25401/7eb5b849.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25500/25401/e7dad54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/25500/25401/5f074e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elimwood Hotel, a Ramada by Wyndham

Maryland Heights

7.4/10

Good

(1013)

"Clean nice room, staff was all very friendly & helpful, exceptionally so. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeanne

CA $122

CA $142 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-Elimwood-Hotel.h25401.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/3e0ca2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/cff3dc72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/cebe4fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/b0c1520e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express St. Louis West - O'Fallon by IHG

O'Fallon

8.6/10

Excellent

(805)

"Clean, well maintained hotel. Friendly staff, great breakfast. Close to shopping and restaurants."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Theresa

CA $133

CA $157 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/7efb516b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/fbaa6227.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/605f47a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/4b6e8a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel St. Louis St. Charles

St. Charles

9.6/10

Exceptional

(1016)

"Great staff and great amenities!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alicia

CA $154

CA $179 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information)

![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/800/704/4cb8e1cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/704/d6609115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/1000000/10000/800/704/557cf01e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/800/704/ba0404e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham St Charles

St. Charles

8.0/10

Very good

(1014)

"Clean room and comfortable bed I would stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

janeice

CA $106

CA $122 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-Super-8-By-Wyndham-St-Charles.h704.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74300/74268/1415da01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Yoga](https://images.trvl-media.com/lodging/1000000/80000/74300/74268/da46554e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/80000/74300/74268/38538fae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee service](https://images.trvl-media.com/lodging/1000000/80000/74300/74268/b995ee68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Fenton

8.8/10

Excellent

(1006)

"Staff was super friendly "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melissa

CA $154

CA $178 total

includes taxes & fees

Oct 22 - Oct 23

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-West-Fenton.h74268.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/918800/918798/8e0321ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/920000/918800/918798/77e0f632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/920000/918800/918798/7aab5b59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/920000/918800/918798/a320a146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Union

Union

8.2/10

Very good

(622)

"All around great place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chris

CA $109

CA $120 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Washington-Hotels-Super-8-By-Wyndham-Union.h918798.Hotel-Information)

![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/ceec5aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/b2add733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/8032c924.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/be73da93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Warrenton

Warrenton

7.4/10

Good

(604)

"I have stayed several times at this hotel, it is always very clean, the staff are super nice and very convenient to I-70; would recommend this hotel and I will definitely stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

CA $83

CA $96 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Warrenton-Hotels-Super-8-By-Wyndham-Warrenton.h460034.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04&regionId=6353634&adults=2&sort=RECOMMENDED&openPlayBack=true)

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Save an average of 15% on thousands of hotels when you're signed in

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## Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

[See all hotels in Defiance](https://www.expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04&adults=2&regionId=6353634)

![](https://mediaim.expedia.com/destination/9/db5eb599ca7c4918fd6575109a51c6ac.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

### Stay near popular Defiance attractions

[](https://expedia.ca/Busch-Stadium-Hotels.0-l502872-0.Travel-Guide-Filter-Hotels)

![Busch Stadium](https://mediaim.expedia.com/destination/1/fc7b602fbc184e7e7e6b56e34fb1afe4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Busch Stadium

5/5(19 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502872)

[](https://expedia.ca/St-Louis-Union-Station-Hotels.0-l502868-0.Travel-Guide-Filter-Hotels)

![St. Louis Union Station](https://mediaim.expedia.com/destination/9/55f06578213cb4d3e5a61c6fa51be851.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### St. Louis Union Station

4.5/5(7 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502868)

[](https://expedia.ca/Gateway-Arch-Hotels.0-l502855-0.Travel-Guide-Filter-Hotels)

![Gateway Arch featuring modern architecture, a city and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/28000/28954-Gateway-Arch.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Gateway Arch

4.5/5(37 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502855)

[](https://expedia.ca/St-Louis-Zoo-Hotels.0-l502878-0.Travel-Guide-Filter-Hotels)

![St. Louis Zoo](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/200000/200067-St-Louis-Zoo.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### St. Louis Zoo

4.5/5(7 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502878)

[](https://expedia.ca/City-Museum-Hotels.0-l6069375-0.Travel-Guide-Filter-Hotels)

![City Museum showing a city as well as children](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199840-City-Museum.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### City Museum

4.5/5(6 reviews)

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6069375)

[](https://expedia.ca/Forest-Park-Hotels.0-l6005687-0.Travel-Guide-Filter-Hotels)

![Forest Park featuring a pond, flowers and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199633-Saint-Louis.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Forest Park

4.5/5(9 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6005687)

## More cheap stays in Defiance

![Americas Best Value Inn & Suites St. Louis, St. Charles Inn](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/c17520b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive, St. Charles, MO

CA $98

CA $114 total

Oct 21 - Oct 22

includes taxes & fees

5.6/10 (1,014 reviews)

[](https://expedia.ca/St-Louis-Hotels-Americas-Best-Value-Inn-Suites-St-Louis.h68132.Hotel-Information)

![Hampton Inn St. Charles St. Peters](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/8c366380_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn St. Charles St. Peters

3720 W Clay St, St. Charles, MO

CA $126

CA $145 total

Nov 18 - Nov 19

includes taxes & fees

8/10 Very Good! (1,017 reviews)

[](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information)

![Relax Inn Saint Charles ](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Relax Inn Saint Charles

3800 Harry S Truman Blvd, St. Charles, MO

CA $85

CA $98 total

Nov 9 - Nov 10

includes taxes & fees

6.4/10 (1,001 reviews)

[](https://expedia.ca/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information)

![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/529fe0ff_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St, St. Charles, MO

CA $172

CA $197 total

Oct 26 - Oct 27

includes taxes & fees

9.4/10 Exceptional! (1,019 reviews)

[](https://expedia.ca/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information)

![Baymont by Wyndham St. Charles](https://images.trvl-media.com/lodging/1000000/50000/41500/41491/8dfa5f2b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Baymont by Wyndham St. Charles

801 Veterans Memorial Parkway, St. Charles, MO

[Get rates](https://expedia.ca/Hotel-Search?startDate=03%2F11%2F2025&endDate=04%2F11%2F2025&selected=41491&PinnedHotelID=41491&HadPinnedHotel=true&regionId=6353634)

7.8/10 Good! (1,000 reviews)

[](https://expedia.ca/St-Louis-Hotels-Baymont-By-Wyndham-St-Charles.h41491.Hotel-Information)

![Best Western Plus St. Louis West-Westport](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/00255b25_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus St. Louis West-Westport

12220 Dorsett Rd, Maryland Heights, MO

CA $121

CA $140 total

Nov 17 - Nov 18

includes taxes & fees

7.8/10 Good! (1,013 reviews)

[](https://expedia.ca/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information)

## Recent reviews of Defiance hotels

![The Wildwood Hotel](//images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg)

### The Wildwood Hotel

5/5 Excellent

"Our room was clean and the shower was hot! Breakfast was pretty good too. The wallpaper was showing a little wear but they were doing some renovations while we were there. We didn’t use the pool or hot tub but they seemed nice. Staff was friendly and helpful! Mostly, we felt super safe! We didn’t worry about a thing and loved the convenient location to Saint Louis."

A verified traveller stayed at The Wildwood Hotel

Posted 1 day ago

[](https://expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information)

![Sonesta ES Suites St. Louis - Chesterfield](//images.trvl-media.com/lodging/1000000/10000/500/422/a42ce99e_y.jpg)

### Sonesta ES Suites St. Louis - Chesterfield

5/5 Excellent

"Clean rooms, pool, kitchen was nice."

A verified traveller stayed at Sonesta ES Suites St. Louis - Chesterfield

Posted 2 days ago

[](https://expedia.ca/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information)

![Wingate by Wyndham St. Louis/Fenton Route 66](//images.trvl-media.com/lodging/1000000/50000/40200/40102/5c35b8a4_y.jpg)

### Wingate by Wyndham St. Louis/Fenton Route 66

5/5 Excellent

"."

A verified traveller stayed at Wingate by Wyndham St. Louis/Fenton Route 66

Posted 2 days ago

[](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Fenton.h40102.Hotel-Information)

![Ameristar Casino Resort and Spa](//images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg)

### Ameristar Casino Resort and Spa

5/5 Excellent

"Awesome stay for a girls night out!! "

A verified traveller stayed at Ameristar Casino Resort and Spa

Posted 3 days ago

[](https://expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information)

![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](//images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg)

### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

5/5 Excellent

"We made a last minute reservation and were pleased with the value. It’s not the newest hotel but we got a spacious two room suite for a great price."

A verified traveller stayed at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Posted 3 days ago

[](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information)

![Hampton Inn St. Charles St. Peters](//images.trvl-media.com/lodging/1000000/30000/20200/20181/8c366380_y.jpg)

### Hampton Inn St. Charles St. Peters

5/5 Excellent

"Clean spaces. When I needed a pack and play they brought one quickly. "

A verified traveller stayed at Hampton Inn St. Charles St. Peters

Posted 3 days ago

[](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information)

![Hollywood Casino & Hotel St. Louis](//images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg)

### Hollywood Casino & Hotel St. Louis

5/5 Excellent

"Great stay would recommend "

A verified traveller stayed at Hollywood Casino & Hotel St. Louis

Posted 4 days ago

[](https://expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information)

![Drury Plaza Hotel St. Louis Creve Coeur](//images.trvl-media.com/lodging/1000000/80000/74700/74657/3c4503ce_y.jpg)

### Drury Plaza Hotel St. Louis Creve Coeur

5/5 Excellent

"Wonderful staff!"

A verified traveller stayed at Drury Plaza Hotel St. Louis Creve Coeur

Posted 4 days ago

[](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Creve-Coeur.h74657.Hotel-Information)

![Drury Plaza Hotel St. Louis Chesterfield](//images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/c1fcfc39_y.jpg)

### Drury Plaza Hotel St. Louis Chesterfield

5/5 Excellent

"Great"

A verified traveller stayed at Drury Plaza Hotel St. Louis Chesterfield

Posted 4 days ago

[](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information)

## Frequently asked questions

### When is the best time to go to Defiance?

> The most popular time to visit Defiance is during the summer months, particularly in July, when the weather is warm and inviting. With average temperatures ranging from 22 to 28°C, it's the superb backdrop for outdoor adventures, whether you're exploring the scenic Maumee River or enjoying local events in the parks.
> 
>   
> 
> During the peak season from July to September, Defiance buzzes with activity. Festivals and community gatherings take place, providing visitors with a delightful opportunity to immerse themselves in the local culture. The vibrant atmosphere makes it ideal for families and couples alike, as there are plenty of outdoor activities, such as hiking, biking, and picnicking, in the surrounding nature.
> 
>   
> 
> If you're looking for a more budget-friendly time to visit, consider late September or early October. While the weather may start to cool slightly, with temperatures around 15 to 20°C, the autumn foliage offers a beautiful setting for sightseeing. This time of year also means fewer crowds, allowing you to enjoy the attractions at a more leisurely pace.

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Defiance hotel for you.

### How can I save on a Defiance hotel booking with Expedia?

> Members always get our best prices. Find our best Defiance hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a Defiance hotel?

> Prices for hotels in Defiance often vary, but you can find a great deal from CA $96 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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-   [Lodges in Wildwood](https://www.expedia.ca/Wildwood-Lodges.d6085106-aaLodges.Travel-Guide-Accommodation)
-   [Motels in Wildwood](https://www.expedia.ca/Wildwood-Motels.d6085106-aaMotels.Travel-Guide-Accommodation)
-   [Townhomes in Wildwood](https://www.expedia.ca/Wildwood-Townhomes.d6085106-aaTownhomes.Travel-Guide-Accommodation)

-   [Flights to Gray Summit](https://www.expedia.ca/Cheap-Flights-To-Gray-Summit.d6055922.Travel-Guide-Flights)
-   [Flights to Wildwood](https://www.expedia.ca/Cheap-Flights-To-Wildwood.d6085106.Travel-Guide-Flights)
-   [Flights from Wildwood](https://www.expedia.ca/lp/flights/6085106/flights-from-wildwood)
-   [Flights from Newton (EWK) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/ewk/sus/newton-to-st-louis)
-   [Flights from Niagara Falls (IAG) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/iag/sus/niagara-falls-to-st-louis)
-   [Flights from Little Rock (LIT) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/lit/sus/little-rock-to-st-louis)
-   [Flights from Poplar Bluff (POF) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/pof/sus/poplar-bluff-to-st-louis)
-   [Flights from Vancouver (YVR) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/yvr/sus/vancouver-to-st-louis)
-   [Flights from Toronto (YYZ) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/yyz/sus/toronto-to-st-louis)

-   [Labadie Vacations](https://www.expedia.ca/Labadie.d3000445125.Destination-Travel-Guides)
-   [Six Flags St. Louis](https://www.expedia.ca/Six-Flags-St-Louis-St-Louis.d6147083.Vacation-Attraction)
-   [Wildwood Vacations](https://www.expedia.ca/Wildwood.d6085106.Destination-Travel-Guides)

-   [Rental cars Spirit of St. Louis airport](https://www.expedia.ca/Car-Rentals-In-Spirit-Of-St-Louis.d6024951.Car-Rental-Guide)
-   [Car rentals near St. Louis Premium Outlets](https://www.expedia.ca/Car-Rentals-In-St-Louis-Premium-Outlets.d553248621561876860.Car-Rental-Guide)
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-   [National Car Rental Rental Cars in Spirit of St. Louis](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Spirit-Of-St-Louis.d6024951-c42.Car-Rental-Guide-Suppliers)
-   [Pickup Car Rentals near Show Me](https://www.expedia.ca/Pickup-Car-Rentals-In-Show-Me.d553248635996618251-tPickup.Car-Rental-Guide-Class)

-   [Book Hotels in Defiance on Expedia.com](https://www.expedia.com/Defiance-Hotels.d6353634.Travel-Guide-Hotels)

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