Title: Book the Best BUSINESS Hotels in Mississippi Gulf Coast in 2026 | Expedia.ca [Mississippi Gulf Coast Travel Guide](https://expedia.ca/Mississippi-Gulf-Coast.dx6058666)[Hotels in Mississippi Gulf Coast](https://expedia.ca/Mississippi-Gulf-Coast-Hotels.d6058666.Travel-Guide-Hotels)[Vacation Rentals in Mississippi Gulf Coast](https://expedia.ca/Mississippi-Gulf-Coast-Vacation-Rentals.d6058666.Travel-Guide-VacationRentals)[Flights to Mississippi Gulf Coast](https://expedia.ca/Cheap-Flights-To-Mississippi-Gulf-Coast.d6058666.Travel-Guide-Flights)[Things to do in Mississippi Gulf Coast](https://expedia.ca/Things-To-Do-In-Mississippi-Gulf-Coast.d6058666.Travel-Guide-Activities)[Mississippi Gulf Coast Car Rentals](https://expedia.ca/Car-Rentals-In-Mississippi-Gulf-Coast.d6058666.Car-Rental-Guide)[Mississippi Gulf Coast Vacation Packages](https://expedia.ca/Mississippi-Gulf-Coast.d6058666.Destination-Travel-Guides) ![Biloxi showing night scenes and a lighthouse](https://images.trvl-media.com/place/603259/b5fbd0cd-abad-4665-9fe3-f5a5344cf939.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Mississippi Gulf Coast Convention & Visitors Bureau ![](https://images.trvl-media.com/place/603259/b5fbd0cd-abad-4665-9fe3-f5a5344cf939.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mississippi Gulf Coast Business Hotels Tonight [Jan 27 - Jan 28](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2026-01-27&endDate=2026-01-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 28 - Jan 29](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2026-01-28&endDate=2026-01-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Mississippi Gulf Coast business-friendly hotels ![2 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/5f7dc204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/0cbf294f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/e4c76492.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room, 1 King Bed, Non Smoking, Terrace](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/12bc909d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Golden Nugget Biloxi [](https://www.expedia.ca/Biloxi-Hotels-Golden-Nugget-Biloxi.h22267.Hotel-Information) Downtown Biloxi 8.0/10 Very good (2,814 reviews) "Great trip! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $86 CA $120 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Biloxi-Hotels-Golden-Nugget-Biloxi.h22267.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/4393bc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/a15494c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/bed9eb06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/8ef31628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hotel Legends [](https://www.expedia.ca/Biloxi-Hotels-The-Hotel-Legends.h44550296.Hotel-Information) Downtown Biloxi 9.6/10 Exceptional (2,593 reviews) "The rooms kept very clean and staff excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $132 CA $163 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Biloxi-Hotels-The-Hotel-Legends.h44550296.Hotel-Information) ![Mini-golf](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/a73e79ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/66bb8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/d724a90b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 8:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/7ef5d4eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scarlet Pearl Casino Resort [](https://www.expedia.ca/Biloxi-Hotels-Scarlet-Pearl-Casino-Resort.h19661502.Hotel-Information) D'Iberville 9.4/10 Exceptional (1,606 reviews) "Beautiful place and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicholas CA $110 CA $123 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Biloxi-Hotels-Scarlet-Pearl-Casino-Resort.h19661502.Hotel-Information) ![Seasonal outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/3568a8ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/17a63a9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/e5486226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/aabb4188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centennial Plaza Resort Gulfport [](https://www.expedia.ca/Biloxi-Hotels-Grand-Centennial-Hotel-Gulfport.h37075152.Hotel-Information) Gulfport 9.2/10 Wonderful (1,002 reviews) "Beautiful place. Convenient location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra CA $147 CA $192 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Biloxi-Hotels-Grand-Centennial-Hotel-Gulfport.h37075152.Hotel-Information) ![Deep-tissue massages, Swedish massages, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/2c58a908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/338f5585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/c562b74d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/0c261a2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Casino Resort [](https://www.expedia.ca/Biloxi-Hotels-Palace-Casino-Resort.h1652862.Hotel-Information) Summerville 9.2/10 Wonderful (3,052 reviews) "Clean, staff nice, amenities awesome, great food!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bryan CA $104 CA $117 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Biloxi-Hotels-Palace-Casino-Resort.h1652862.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/w5757h3835x3y5-43ed1385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/w5758h3835x0y5-8cda01b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/w5755h3835x5y5-45c21c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/w5760h3835x0y5-6d77deb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Biloxi [](https://www.expedia.ca/Biloxi-Hotels-Hyatt-Place-Biloxi.h16127483.Hotel-Information) Biloxi 8.8/10 Excellent (1,209 reviews) "Amazing facility and stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ly CA $121 CA $136 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Biloxi-Hotels-Hyatt-Place-Biloxi.h16127483.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/5a7f80d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/f7937ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![8 restaurants, breakfast, lunch, dinner served; local cuisine](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/420464c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/bd85f7b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harrah’s Gulf Coast – A Caesars Rewards Destination [](https://www.expedia.ca/Biloxi-Hotels-Harrahs-Gulf-Coast.h67068.Hotel-Information) Summerville 7.6/10 Good (1,418 reviews) "Room was great and the staff was awesome" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roberta CA $69 CA $106 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Biloxi-Hotels-Harrahs-Gulf-Coast.h67068.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/4c2332ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/w1998h2492x0y8-c9ab34b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/7ffb817a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/ff7d4212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White House Hotel [](https://www.expedia.ca/Biloxi-Hotels-White-House-Hotel.h8751651.Hotel-Information) Biloxi 8.8/10 Excellent (1,015 reviews) "Very pleasant stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colton CA $144 CA $162 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Biloxi-Hotels-White-House-Hotel.h8751651.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/b4a284f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/e1c21b30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking (Deluxe Executive Room)](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/1c2c475c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/7ee5474d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Hattiesburg - I-59 [](https://www.expedia.ca/Hattiesburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Hattiesburg-I-59.h9127721.Hotel-Information) Hattiesburg 8.6/10 Excellent (1,536 reviews) "Room was very clean and staff very friendly and nice. Great breakfast - hot and cold choices!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara Margaret CA $100 CA $110 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Hattiesburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Hattiesburg-I-59.h9127721.Hotel-Information) ![Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/2000000/1680000/1676200/1676200/539d4e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/2000000/1680000/1676200/1676200/6e20d174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1680000/1676200/1676200/dc9eb814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1680000/1676200/1676200/d4363200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Hattiesburg [](https://www.expedia.ca/Hattiesburg-Hotels-Microtel-Inn-Suites-By-Wyndham-Hattiesburg.h1676200.Hotel-Information) Hattiesburg 8.6/10 Excellent (1,005 reviews) "Amazing stay and staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $92 CA $101 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Hattiesburg-Hotels-Microtel-Inn-Suites-By-Wyndham-Hattiesburg.h1676200.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-10&endDate=2026-02-11®ionId=6058666&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Mississippi Gulf Coast Hotel Reviews ![White House Hotel](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/w1998h2492x0y8-c9ab34b7_y.jpg) ### White House Hotel 10/10 Excellent "Room was very nice. Bar and restaurant was good and convenient. " [](https://expedia.ca/Biloxi-Hotels-White-House-Hotel.h8751651.Hotel-Information) ![Comfort Suites Gulfport](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958794/5de09bb8_y.jpg) ### Comfort Suites Gulfport 10/10 Excellent "Super clean and the staff was so helpful and friendly. Great location. Lots of places to eat super close. Only about 10-12 minutes from the beach area/casino We would highly recommend " [](https://expedia.ca/Biloxi-Hotels-Comfort-Suites-Gulfport.h2958794.Hotel-Information) ![Hard Rock Hotel & Casino Biloxi](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731566/7e1bb110_y.jpg) ### Hard Rock Hotel & Casino Biloxi 10/10 Excellent "Yes" [](https://expedia.ca/Biloxi-Hotels-Hard-Rock-Hotel-Casino-Biloxi.h1731566.Hotel-Information) ![Harrah’s Gulf Coast – A Caesars Rewards Destination](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/5a7f80d4_y.jpg) ### Harrah’s Gulf Coast – A Caesars Rewards Destination 10/10 Excellent "Everything was great" [](https://expedia.ca/Biloxi-Hotels-Harrahs-Gulf-Coast.h67068.Hotel-Information) ![Best Western Seaway Inn](https://images.trvl-media.com/lodging/1000000/10000/2300/2257/b670a344_y.jpg) ### Best Western Seaway Inn 10/10 Excellent "We stayed here 5 nights in June and were so impreesed with the cleanliness and the wonderful hot breakfasts!" [](https://expedia.ca/Biloxi-Hotels-Best-Western-Seaway-Inn.h2257.Hotel-Information) ![Palace Casino Resort](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/6049152a_y.jpg) ### Palace Casino Resort 10/10 Excellent "Great hotel and casino! Nice room and smoke free, great food options, great service! The café has good cakes and this is the best casino to watch the horse races! " [](https://expedia.ca/Biloxi-Hotels-Palace-Casino-Resort.h1652862.Hotel-Information) ![Beau Rivage](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/b66654c5_y.jpg) ### Beau Rivage 10/10 Excellent "Yes" [](https://expedia.ca/Biloxi-Hotels-Beau-Rivage.h199634.Hotel-Information) ![IP Casino Resort Spa - Biloxi](https://images.trvl-media.com/lodging/1000000/90000/85100/85080/e0a1ead8_y.jpg) ### IP Casino Resort Spa - Biloxi 10/10 Excellent "Room was great. Decent view if the window had not been so filthy. Very disappointing in that respect. " [](https://expedia.ca/Biloxi-Hotels-IP-Casino-Resort-Spa-Biloxi.h85080.Hotel-Information) ![Treasure Bay Casino and Hotel - Adults Only](https://images.trvl-media.com/lodging/1000000/490000/483500/483470/601c9588_y.jpg) ### Treasure Bay Casino and Hotel - Adults Only 10/10 Excellent "The Room was spottless and the staff was very polite and helpful. The regular noise from the casino was 1 issues in the room and door leading to the pation could be a solid to help out with the outside noise." [](https://expedia.ca/Biloxi-Hotels-Treasure-Bay-Casino-And-Hotel-Adults-Only.h483470.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Mississippi Gulf Coast cost? ### What are the best business-friendly hotels in Mississippi Gulf Coast? ### How many business-friendly hotels are there in Mississippi Gulf Coast? ### What are the best cheap business-friendly hotels in Mississippi Gulf Coast? ### Are there any family-friendly hotels in Mississippi Gulf Coast that are also business friendly? ### Are there any 5-star business-friendly hotels in Mississippi Gulf Coast? ### Why book your business-friendly hotel in Mississippi Gulf Coast with Expedia? ### How can I find cheap business-friendly hotels in Mississippi Gulf Coast? ### What is there to do in Mississippi Gulf Coast near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Adults Only Resorts & in Bayou View ](https://www.expedia.ca/Bayou-View-Gulfport-Hotels-Adults-Only-Resorts.0-n553248635976473839-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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