Title: Book the Best Central San Diego LUXURY Hotels - Upscale Hotels in Central San Diego, CA | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![Balboa Park featuring aircraft and interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21283-Balboa-Park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Central San Diego, CA ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central San Diego Luxury Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-30&endDate=2025-10-31&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-31&endDate=2025-11-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Central San Diego Luxury Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2557x3y3-6971afdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3840h2556x0y3-1f0ee309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/a6c5898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seven Seas Mission Valley 7.8/10 Good (2982) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $118 CA $136 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a73644b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/c007c44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/8104aff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kings Inn San Diego Mission Valley 8.8/10 Excellent (3505) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $105 CA $121 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 2 Queen Beds, Accessible, Non Smoking (Mobility/Hearing Impaired)](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/30557300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3456147f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/c491024e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego Hotel Circle Mission Valley 8.0/10 Very good (2369) "Not a bad place to stay, and was clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Seth CA $116 CA $134 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/4be20fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/ed8e473b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/7c177216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/bda1d22b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pleasant Inn Clairemont 8.4/10 Very good (1201) "Great place to stay for the price. Would definitely stay again when in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $130 CA $150 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/0a66ad12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/724f034d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/b197cd41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/8399b5a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency La Jolla University City 8.8/10 Excellent (1003) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brendan R CA $222 CA $306 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information) ![Hot springs](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/d27fd38e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/87f93e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/d2b2734e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Atwood Hotel San Diego - SeaWorld/Zoo Mission Valley 8.0/10 Very good (1779) "Clean, Nice staff, Convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashlee CA $111 CA $128 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/ed3f3759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/66a1c9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/4093c285.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/56300/56212/31240634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham San Diego Hotel Circle Mission Valley 7.2/10 Good (551) "Business friendly, great staff good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) angelica CA $101 CA $116 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Super-8-By-Wyndham-San-Diego-Hotel-Circle.h56212.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/eb7ba8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/96ca9e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/def5a1aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/c47d4d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Town Western Inn & Suites Old Town San Diego 7.4/10 Good (1024) "This was a cute stay in a cute area for so much to do! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $133 CA $150 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/e1f8ca63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/567b3048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/15f7656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996100/996099/ec648405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Diego, CA - Hotel Circle - Mission Valley Mission Valley 6.8/10 (1485) "Clean, Easy check in, quite" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $106 CA $121 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h996099.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/804dc72b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/584e67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/bc796e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/e2b8ef1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Hotel & Conference Center by Wyndham San Diego North Kearny Mesa 8.0/10 Very good (942) "Very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=6056570&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Central San Diego Hotel Reviews ![DoubleTree by Hilton Hotel San Diego - Mission Valley](//images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "The staff was friendly. The rooms were clean. It had a great bar and outdoor area to relax. " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Kings Inn San Diego](//images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "All of the above" [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](//images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Na" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "standard room, only thing we kind of have issues with was our key wasn't working properly when leaving the parking, so we would just press on the call button then they'll eventually open the gate." [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](//images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "Amazing Stay at Embassy Suites La Jolla! My experience at Embassy Suites La Jolla was absolutely fantastic from start to finish. The staff went above and beyond—friendly, professional, and always ready to help with a smile. The suites were spotless, spacious, and comfortable, with everything you need for a relaxing stay. The complimentary breakfast was one of the best I’ve had at any hotel—fresh, hot, and plenty of variety. The made-to-order omelets were a great touch! I also loved the evening reception; it’s a nice way to unwind with drinks and snacks in a comfortable setting. The location couldn’t be better—right across from Westfield UTC Mall, close to great restaurants, and just a short drive to the beach. The hotel feels modern, safe, and well-maintained, with a great indoor pool and fitness area. Overall, Embassy Suites La Jolla exceeded my expectations in every way. Whether you’re visiting for business, family, or a quick getaway, this place is a winner. I’ll definitely be coming back!" [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ![Country Inn & Suites by Radisson, San Diego North, CA](//images.trvl-media.com/lodging/1000000/20000/16600/16546/abd318f6_y.jpg) ### Country Inn & Suites by Radisson, San Diego North, CA 10/10 Excellent "The hotel is very clean and comfortable. Very quick and friendly service every time I needed assistance. The breakfast is great! Lots of options for food, and the breakfast area is spacious, bright, and clean. " [](https://expedia.ca/San-Diego-Hotels-Country-Inn-Suites-By-Radisson.h16546.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](//images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "Very clean everywhere and room spotless. Staff very friendly. " [](https://expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Town and Country San Diego](//images.trvl-media.com/lodging/1000000/30000/21400/21394/bbee5f13_y.jpg) ### Town and Country San Diego 10/10 Excellent "We love it here at Town and Country. We come atleast once a year. Rooms are always very clean. The kids love the pools especially the water slide and entertainment they offer. We love the accessibility of the coffee shop and restaurants near by. As well as the shopping center right behind the resort. " [](https://expedia.ca/San-Diego-Hotels-Town-And-Country-San-Diego.h21394.Hotel-Information) ![DoubleTree by Hilton San Diego - Hotel Circle](//images.trvl-media.com/lodging/1000000/30000/25600/25536/983f923b_y.jpg) ### DoubleTree by Hilton San Diego - Hotel Circle 10/10 Excellent "Yes" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Hotel-Circle.h25536.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - More ways to book - [Cheap Hotels in Birdland](https://www.expedia.ca/Birdland-San-Diego-Hotels-Cheap-Hotels.0-n553248635976479135-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - 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