Title: Central San Diego Guest Houses from CA $120 | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in Central San Diego from CA $120 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-02&endDate=2026-01-04&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-16&endDate=2026-01-18&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-02-13&endDate=2026-02-15&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Central San Diego guest houses ![Fridge, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/158cade6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/08361f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/f7196783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/075d2a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart of SD | Zoo Nearby | Private Patio | Central [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) Mid-City 8.0/10 Very good (4) "Such a cute and perfect spot! Had all the thoughtful touches. Was very cozy, bed was comfy and little patio was great. I would definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanya R. CA $110 CA $261 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/d4d636ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/eb794f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/0d3d76b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/d544292c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio [](https://www.expedia.ca/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) University City 10/10 Exceptional (1) "Great place,near my son so was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) noel o. CA $282 CA $595 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/da8f2406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed (Wedgewood) | Living area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/6988f242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/aea9aa0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/f6cdb0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Hacienda [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) Spring Valley 9.2/10 Wonderful (538) "Great room. Fun staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $222 CA $240 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40601c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/06ca5233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/1dcb5057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/665db20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Primero Hotel [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) Downtown Chula Vista 9.2/10 Wonderful (1001) "Well maintained and the staff are great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Junzky CA $109 CA $120 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) ![TV, offices](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/e9768cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/cf0454ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/aca5b4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/86755ec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Little Oasis Summ [](https://www.expedia.ca/Escondido-Hotels-The-Little-Oasis-Summ.h113902265.Hotel-Information) Country Club CA $101 CA $395 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Escondido-Hotels-The-Little-Oasis-Summ.h113902265.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/0fc89a86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/ddb692db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, wheelchair access](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/f64903ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/1b5262f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage On The Greens - Stunning Golf Course Views [](https://www.expedia.ca/San-Diego-Hotels-Cottage-On-The-Greens-Studio.h99223393.Hotel-Information) Rancho Bernardo 10/10 Exceptional (8) "It all went smoothly! The owners were very nice people, that made us feel welcome!A lovely location! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard S. CA $188 CA $707 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/San-Diego-Hotels-Cottage-On-The-Greens-Studio.h99223393.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/35000000/34120000/34110700/34110608/647e06ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/35000000/34120000/34110700/34110608/c0a78e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34120000/34110700/34110608/48961c30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34120000/34110700/34110608/14da40a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Beach gem. Enjoy Ocean breezes and sunsets from this darling get-a-way [](https://www.expedia.ca/San-Diego-Hotels-Ocean-Beach-Gem-Enjoy-Ocean-Breezes-And-Sunsets-From-This-Darling-Get-A-Way.h34110608.Hotel-Information) Point Loma 9.8/10 Exceptional (90) "Convenient and comfortable for our short stay. Lovely neighborhood!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathy D. CA $200 CA $562 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/San-Diego-Hotels-Ocean-Beach-Gem-Enjoy-Ocean-Breezes-And-Sunsets-From-This-Darling-Get-A-Way.h34110608.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w902h683x61y0-c090cafe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w4000h2662x0y0-3e9c584a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w905h683x59y0-0e1b8717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/aa12fb27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Encinitas - The Leucadia Beach Grotto - Pet-Friendly & Steps to Everything! [](https://www.expedia.ca/Encinitas-Hotels-Few-Blocks-From-The-Beach-Restaurants-Steps-Away-From-Private-Poolside.h95355923.Hotel-Information) Leucadia 10/10 Exceptional (15) "Great place and very accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas P. CA $254 CA $452 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/Encinitas-Hotels-Few-Blocks-From-The-Beach-Restaurants-Steps-Away-From-Private-Poolside.h95355923.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/5afb3714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/514bc114.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/6e926ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/a8221a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly Built Guest Home [](https://www.expedia.ca/San-Diego-Hotels-Newly-Built-Guest-Home.h91135120.Hotel-Information) Mira Mesa 10/10 Exceptional (36) "I would highly recommended to stay this property. It’s super close to everything! Brian super responsive to everything you need during your stays. It’s perfect for our family! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberta C. CA $414 CA $784 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Newly-Built-Guest-Home.h91135120.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-04&endDate=2026-01-05®ionId=6056570&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation) ## Top Central San Diego Hotel Reviews ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Very clean and tidy, super beautiful." [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![DoubleTree by Hilton San Diego - Hotel Circle](https://images.trvl-media.com/lodging/1000000/30000/25600/25536/983f923b_y.jpg) ### DoubleTree by Hilton San Diego - Hotel Circle 10/10 Excellent "All are good I don’t use the restaurant or pool " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Hotel-Circle.h25536.Hotel-Information) ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Easy access to where I needed to be & lots of food options nearby at the mall. Clean & comfortable!" [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Sheraton Mission Valley San Diego Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Excellent service, great breakfast selection. Staff as always, very helpful, pleasant. Always enjoy our stay." [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![Four Points by Sheraton San Diego](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d216d27d_y.jpg) ### Four Points by Sheraton San Diego 10/10 Excellent "Great stay" [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego.h23651.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Staff was friendly room was very clean " [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Nice room, good ambiance, central location " [](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Great service " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Nice staff, clean and spacious room. Waffle restaurant 100-200 feet away. Had a lovely stay!" [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ## Find out more about Central San Diego ## Central San Diego Guest Houses information | Number of reviews | 1,542 | | ----------------- | --------------- | | Accommodation | 19 Guest Houses | | Lowest Price | CA $120 | | Highest Price | CA $784 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Aparthotels in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apart-Hotels.d800122-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apartments.d800122-aaApartments.Travel-Guide-Accommodation) - [Condo Resorts in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Condominium-Resort.d800122-aaCondominiumResort.Travel-Guide-Accommodation) - [Inns in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Inns.d800122-aaInns.Travel-Guide-Accommodation) - 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