Title: Central San Diego Guest Houses | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![Balboa Park featuring aircraft and interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21283-Balboa-Park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in Central San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-11-21&endDate=2025-11-23&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-19&endDate=2025-12-21&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Central San Diego Guest Houses ![Fridge, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/aca60f31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/20fea243.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/12d034a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/3f572155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart of SD | Zoo Nearby | Private Patio | Central Mid-City 8.0/10 Very good (4) "Such a great spot for a little getaway! A Cozy room with everything you need to enjoy your vacation stressfree. I would definitely stay here again in the future!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zackery B. CA $126 CA $280 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/da8f2406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/6d6bdbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/f6cdb0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/aea9aa0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Hacienda Spring Valley 9.2/10 Wonderful (525) "Beautiful place, kind staff. We are glad we found this place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allison CA $174 CA $188 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40601c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/06ca5233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/665db20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/1dcb5057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Primero Hotel Chula Vista 9.2/10 Wonderful (1001) "Cozy family style " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felipe CA $131 CA $144 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/e31fedb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/3c17e09a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/244ce47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/b4f1d918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 1-bed, 1-bath, kitchenette Guest House in San Diego. Mount Hope 10/10 Exceptional (43) "It was in a convenient location, clean and had everything we needed. Perfect for two people! We would stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dillon H. CA $120 CA $265 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/San-Diego-Hotels-Cozy-1-Bed.h97071912.Hotel-Information) ![TV, offices](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/e9768cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/w1194h673x3y0-99cf01e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/cf0454ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/aca5b4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Little Oasis Summ Country Club CA $113 CA $418 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Escondido-Hotels-The-Little-Oasis-Summ.h113902265.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/0fc89a86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/1b5262f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/fb7f9bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, wheelchair access](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/f64903ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage On The Greens - Stunning Golf Course Views Rancho Bernardo 10/10 Exceptional (8) "Mark made us feel welcome and was responsive to our needs. The studio apartment was perfect for us as we visited with grandkids and family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven W. CA $190 CA $725 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/San-Diego-Hotels-Cottage-On-The-Greens-Studio.h99223393.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w902h683x61y0-c090cafe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w4000h2662x0y0-3e9c584a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w4000h2662x0y0-eda5a9de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/aa12fb27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Encinitas - The Leucadia Beach Grotto - Pet-Friendly & Steps to Everything! Leucadia 10/10 Exceptional (13) "Great place and very accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas P. CA $232 CA $432 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Encinitas-Hotels-Few-Blocks-From-The-Beach-Restaurants-Steps-Away-From-Private-Poolside.h95355923.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/198e6a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/505cfdc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books, streaming services](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/ab7e7ec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/3706623f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockaway North - Family Friendly, Garage Parking & Laundry Mission Beach 9.8/10 Exceptional (26) "We absolutely love the location of this VRBO. 1 minute to the ocean and 2 minutes to the bay side. Many great restaurants a short walk from the condo. The condo itself is as described. The communication between Keeley and I was really quick. It was so nice having the beach chairs and umbrella available to us at all times. The bed was super comfy and so many pillow types to choice from which was amazing. We will definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlene R. CA $238 CA $548 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/San-Diego-Hotels-Rockaway-North-Family-Friendly.h92449548.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/5afb3714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/a8221a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/514bc114.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/6e926ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly Built Guest Home Mira Mesa 10/10 Exceptional (35) "Spotless, nice location, and great host." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Akiko J. CA $379 CA $744 total includes taxes & fees Nov 18 - Nov 19 [](https://www.expedia.ca/San-Diego-Hotels-Newly-Built-Guest-Home.h91135120.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-08&endDate=2025-11-09®ionId=6056570&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation) ## Top Central San Diego Hotel Reviews ![Lafayette Hotel & Club](//images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Such a cool, retro vibe Hotel, beautiful bedroom, with a Diner, bowling alley, bar and swimming pool all on site. Great experience! " [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Country Inn & Suites by Radisson, San Diego North, CA](//images.trvl-media.com/lodging/1000000/20000/16600/16546/abd318f6_y.jpg) ### Country Inn & Suites by Radisson, San Diego North, CA 10/10 Excellent "Hotel was clean and conveniently located near restaurants and such. " [](https://expedia.ca/San-Diego-Hotels-Country-Inn-Suites-By-Radisson.h16546.Hotel-Information) ![Ramada Suites by Wyndham San Diego/Hotel Circle Area](//images.trvl-media.com/lodging/1000000/20000/11600/11553/43298e98_y.jpg) ### Ramada Suites by Wyndham San Diego/Hotel Circle Area 10/10 Excellent "AC was good room was clean 80% Just OLD" [](https://expedia.ca/San-Diego-Hotels-Ramada-Suites-By-Wyndham-San-Diego.h11553.Hotel-Information) ![Town and Country San Diego](//images.trvl-media.com/lodging/1000000/30000/21400/21394/bbee5f13_y.jpg) ### Town and Country San Diego 10/10 Excellent "Be back soon" [](https://expedia.ca/San-Diego-Hotels-Town-And-Country-San-Diego.h21394.Hotel-Information) ![Courtyard by Marriott San Diego Mission Valley/Hotel Circle](//images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/43ae1d02_y.jpg) ### Courtyard by Marriott San Diego Mission Valley/Hotel Circle 10/10 Excellent "Had no complications at all, very happy with the stay, didn't get to try the pool, although I had to find somewhere else to park because it's $30 a night at the building." [](https://expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Mission-ValleyHotel-Circle.h1987617.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](//images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "Easy check in and great office staff. Clean rooms and there is a microwave/ fridge in every room. Free parking is definitely a plus." [](https://expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Kings Inn San Diego](//images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Our hotel floor felt like there was sand all over the ground. " [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Sheraton Mission Valley San Diego Hotel](//images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Comfortable room, very quiet, nice amenities " [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](//images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Dennis at the front desk was jus fantastic! He was so helpful and efficient…great customer service! Best ive had so far from many hotels" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ## Find out more about Central San Diego ## Central San Diego Guest Houses information | Number of reviews | | | --- | --- | | Accommodation | Guest Houses | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Aparthotels in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apart-Hotels.d800122-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apartments.d800122-aaApartments.Travel-Guide-Accommodation) - [Condo Resorts in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Condominium-Resort.d800122-aaCondominiumResort.Travel-Guide-Accommodation) - [Inns in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Inns.d800122-aaInns.Travel-Guide-Accommodation) - 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