Title: Best Central San Diego Apart hotels | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![Balboa Park featuring aircraft and interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21283-Balboa-Park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Apart Hotels in Central San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-31&endDate=2025-11-02&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-11-07&endDate=2025-11-09&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-11-21&endDate=2025-11-23&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-19&endDate=2025-12-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Central San Diego Aparthotels ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/79e8f033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills Middletown 9.6/10 Exceptional (92) "Great place to stay with my family of 9!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica CA $178 CA $248 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/87b3eb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/84cf0a12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/12939858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel Hillcrest 8.2/10 Very good (242) "Convenient in a great walkable area of town. Staff was great from check-in to check-out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $135 CA $152 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b82a5191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/d0f0db5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/112e5b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/w2000h1293x0y90-00acac65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter Downtown San Diego 9.2/10 Wonderful (479) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $198 CA $271 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk)](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/0f983451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/26d61c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/10234b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Private kitchen](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/fbd31f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Gaslamp Quarter San Diego Downtown San Diego 8.0/10 Very good (140) "Plenty of restaurants all in walking distance. Given the area of the room could be quieter but other than that it was a very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melisa CA $132 CA $151 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) ![Queen Bed Studio with Patio | Terrace/patio](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/d0adc246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shared kitchen facilities](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/cab2e937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Bed Studio](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/6f1221b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/34f7fb43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Italy Inn - Limited Service Apart Hotel Downtown San Diego 8.2/10 Very good (83) "Loved my stay there! I will definitely be back :)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ramya alexis CA $147 CA $167 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Diego-Hotels-Little-Italy-Inn.h114912134.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87270000/87268900/87268820/2dd56f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/88000000/87270000/87268900/87268820/f84750bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/88000000/87270000/87268900/87268820/5da5be87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave](https://images.trvl-media.com/lodging/88000000/87270000/87268900/87268820/601dd29c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fully Furnished Style 2 BHK - 1 BATH Apt in San Diego Poway-Miramar with Parking Poway 8.8/10 Excellent (11) "It was a great experience was Jason was great. The hotel itself was great. Everything about it was awesome" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry C. CA $227 CA $303 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Poway-Hotels-Corporate-2-Bed-Room-Apt-In-San-Diego-Poway-Miramar.h87268820.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/aa0ca94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/9ea3f4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, 2 Bedrooms](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/ad340e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/7d574065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Little Italy San Diego Downtown San Diego 9.6/10 Exceptional (331) "The amenities are world-class!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander CA $188 CA $369 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04®ionId=6056570&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Apart-Hotels.d6056570-aaApartHotels.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Apart-Hotels.d6056570-aaApartHotels.Travel-Guide-Accommodation) ## Top Central San Diego Hotel Reviews ![Best Western Inn & Suites San Diego – Zoo/SeaWorld Area ](//images.trvl-media.com/lodging/1000000/50000/40800/40745/a5f33771_y.jpg) ### Best Western Inn & Suites San Diego – Zoo/SeaWorld Area 10/10 Excellent "Thank you " [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Super easy check in process, staff was extremely hospitable. My room was comfortable as well. Great job Hilton" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Great for the price" [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Legacy Resort Hotel & Spa](//images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Quick one night stay after a day at San Diego Zoo. Room was comfortable and quiet. Restaurant on site is absolutely delicious. Self parking @ $35 per night was more reasonable than most, and parking was easy. We would absolutely stay again. " [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](//images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "It was a quick over night stay. Did not use any additional amenities. Always enjoy the warm cookies!" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Clean room awesome staff and quiet space " [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Lafayette Hotel & Club](//images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "The decorative details within the rooms and around the property we incredible" [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Ramada Suites by Wyndham San Diego/Hotel Circle Area](//images.trvl-media.com/lodging/1000000/20000/11600/11553/43298e98_y.jpg) ### Ramada Suites by Wyndham San Diego/Hotel Circle Area 10/10 Excellent "Great place. Needs a renovation though…" [](https://expedia.ca/San-Diego-Hotels-Ramada-Suites-By-Wyndham-San-Diego.h11553.Hotel-Information) ![San Diego Marriott Mission Valley](//images.trvl-media.com/lodging/1000000/10000/8400/8332/21e561fb_y.jpg) ### San Diego Marriott Mission Valley 10/10 Excellent "Air conditioning Bed was very comfortable " [](https://expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Mission-Valley.h8332.Hotel-Information) ## Find out more about Central San Diego ## Central San Diego Aparthotels information | Number of reviews | | | --- | --- | | Accommodation | Aparthotels | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Aparthotels in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apart-Hotels.d800122-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apartments.d800122-aaApartments.Travel-Guide-Accommodation) - 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[Safari Tentalow in San Diego County](https://www.expedia.ca/San-Diego-County-Safari-Tentalow.d178304-aaSafariTentalow.Travel-Guide-Accommodation) - [San Diego Hotels](https://www.expedia.ca/San-Diego-Hotels.d3073.Travel-Guide-Hotels) - [Flights to San Diego](https://www.expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights) - [Flights from Montgomery Field](https://www.expedia.ca/lp/airports/myf/flights-from-montgomery-field-airport) - [Flights from Bishop (BIH) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bih/myf/bishop-to-san-diego) - [Flights from Bellingham (BLI) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bli/myf/bellingham-to-san-diego) - [Flights from Boston (BOS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bos/myf/boston-to-san-diego) - [Flights from Burlington (BTV) to San Diego (MYF)](https://www.expedia.ca/lp/flights/btv/myf/burlington-to-san-diego) - [Flights from Borrego Springs (BXS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bxs/myf/borrego-springs-to-san-diego) - 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