Title: Book the Best North Central Florida LUXURY Hotels - Upscale Hotels in North Central Florida, FL | Expedia.ca [North Central Florida Travel Guide](https://expedia.ca/North-Central-Florida.dx6233773)[Hotels in North Central Florida](https://expedia.ca/North-Central-Florida-Hotels.d6233773.Travel-Guide-Hotels)[Vacation Rentals in North Central Florida](https://expedia.ca/North-Central-Florida-Vacation-Rentals.d6233773.Travel-Guide-VacationRentals)[Flights to North Central Florida](https://expedia.ca/Cheap-Flights-To-North-Central-Florida.d6233773.Travel-Guide-Flights)[Things to do in North Central Florida](https://expedia.ca/Things-To-Do-In-North-Central-Florida.d6233773.Travel-Guide-Activities)[North Central Florida Car Rentals](https://expedia.ca/Car-Rentals-In-North-Central-Florida.d6233773.Car-Rental-Guide)[North Central Florida Vacation Packages](https://expedia.ca/North-Central-Florida.d6233773.Destination-Travel-Guides) ![Gainesville featuring modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/61000/61913-Gainesville.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in North Central Florida, FL ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on North Central Florida Luxury Hotels Tonight [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-09-26&endDate=2025-09-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-09-27&endDate=2025-09-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-09-26&endDate=2025-09-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top North Central Florida Luxury Hotels ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/2aec1127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/27b8f8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/147eb861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/2eb44850.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont By Wyndham Gainesville I-75 Gainesville 5.4/10 (1002) "Great" CA $80 CA $106 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Gainesville-Hotels-Baymont-By-Wyndham-Gainesville.h18915.Hotel-Information) ![Premium bedding, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/c251e287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/cd217d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/62d30ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/cb9a0faf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palms Garden Inn Lake City 7.4/10 Good (557) "Dated but clean and friendly." CA $91 CA $102 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Lake-City-Hotels-Palms-Garden-Inn.h40753.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/1bfc5692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/fddc9a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/ad8fe69d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/8ce5f9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Lake City Lake City 8.8/10 Excellent (1000) "Friendly staff. Clean and comfortable rooms!" CA $94 CA $106 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Lake-City-Hotels-Americas-Best-Value-Inn-Lake-City.h1039754.Hotel-Information) ![Soundproofing, bed sheets](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/bf712c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/eb197530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/8ac5b21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/6d118001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Driftwood Inn Lake City 7.8/10 Good (747) "Good location " CA $78 CA $88 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Lake-City-Hotels-Driftwood-Inn.h9724310.Hotel-Information) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/d3372ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/65c924d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/62b4db64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/ab5ce2f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Gainesville University I-75 Gainesville 5.6/10 (1006) "I enjoyed the stay" CA $94 CA $105 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Gainesville-Hotels-Days-Inn-By-Wyndham-Gainesville-University-I-75.h19555.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/0450f0b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/89c63699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, 1 Double Bed, Kitchen](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/e8072106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/8fcede96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Gainesville I-75 Gainesville 6.2/10 (1004) "Nice place" CA $88 CA $99 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Gainesville-Hotels-WoodSpring-Suites-Gainesville-I-75.h3779376.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/a1a33286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/cecd35c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/8cb7bb5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/9d1d7d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Waldo Inn and Suites Waldo 8.8/10 Excellent (918) "Great staff!! Room was clean and convenient. " CA $118 CA $133 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/30efa263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/1827e91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/6e19cc8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/1512c64c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gainesville Lodge Gainesville 7.4/10 Good (543) "Check in and check out was super easy and yhe staff was great. Very respondive to text and informative." CA $99 CA $112 total includes taxes & fees Sep 27 - Sep 28 [](https://www.expedia.ca/Gainesville-Hotels-Gainesville-Lodge.h9724836.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/7dbdcf15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/58180c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/50a7bef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/w3839h2551x0y3-310d80bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton University of Florida Conference Center Gainesville Gainesville 8.4/10 Very good (1008) "It was a wonderful stay and very clean. " CA $156 CA $175 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Gainesville-Hotels-Hilton-University-Of-Florida-Conference-Center-Gainesville.h475205.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1210da70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1c3421f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/c37dfd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/5c4d5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Gainesville I-75 Hospital University Area Gainesville 7.2/10 Good (1011) "A very good hotel, staff were friendly and welcoming. " CA $66 CA $75 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=6233773&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top North Central Florida Hotel Reviews ![Best Western Gateway Grand](//images.trvl-media.com/lodging/1000000/160000/151100/151041/9a241e09_y.jpg) ### Best Western Gateway Grand 10/10 Excellent "Best breakfast of all the motels I’ve been to " [](https://expedia.ca/Gainesville-Hotels-Best-Western-Gateway-Grand.h151041.Hotel-Information) ![Country Inn & Suites by Radisson, Gainesville, FL](//images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/8584a629_y.jpg) ### Country Inn & Suites by Radisson, Gainesville, FL 10/10 Excellent "Kept up very well " [](https://expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![DoubleTree by Hilton Gainesville](//images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg) ### DoubleTree by Hilton Gainesville 10/10 Excellent "The service was excellent. " [](https://expedia.ca/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![Days Inn by Wyndham Gainesville University I-75](//images.trvl-media.com/lodging/1000000/20000/19600/19555/d3372ae4_y.jpg) ### Days Inn by Wyndham Gainesville University I-75 10/10 Excellent "I enjoyed the stay" [](https://expedia.ca/Gainesville-Hotels-Days-Inn-By-Wyndham-Gainesville-University-I-75.h19555.Hotel-Information) ![Quality Inn & Suites Ocala I-75](//images.trvl-media.com/lodging/1000000/20000/13100/13021/a4abf0dd_y.jpg) ### Quality Inn & Suites Ocala I-75 10/10 Excellent "Excellent!!!" [](https://expedia.ca/Ocala-Hotels-Quality-Inn-Suites-I-75.h13021.Hotel-Information) ![Hilton Garden Inn Gainesville](//images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/1560249f_y.jpg) ### Hilton Garden Inn Gainesville 10/10 Excellent "The only way " [](https://expedia.ca/Gainesville-Hotels-Hilton-Garden-Inn-Gainesville.h1631322.Hotel-Information) ![Sleep Inn & Suites University/Shands](//images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg) ### Sleep Inn & Suites University/Shands 10/10 Excellent "Pretty nice place to stay" [](https://expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - More ways to book - [Green Hotels in Daytona Beach](https://www.expedia.ca/Daytona-Beach-Hotels-Green-Sustainable.0-0-d6023995-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts and in Daytona Beach](https://www.expedia.ca/Daytona-Beach-Hotels-Honeymoon-Hotels.0-0-d6023995-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - 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