Title: Book the Best North Central Florida LUXURY Hotels - Upscale Hotels in North Central Florida, FL | Expedia.ca [North Central Florida Travel Guide](https://expedia.ca/North-Central-Florida.dx6233773)[Hotels in North Central Florida](https://expedia.ca/North-Central-Florida-Hotels.d6233773.Travel-Guide-Hotels)[Vacation Rentals in North Central Florida](https://expedia.ca/North-Central-Florida-Vacation-Rentals.d6233773.Travel-Guide-VacationRentals)[Flights to North Central Florida](https://expedia.ca/Cheap-Flights-To-North-Central-Florida.d6233773.Travel-Guide-Flights)[Things to do in North Central Florida](https://expedia.ca/Things-To-Do-In-North-Central-Florida.d6233773.Travel-Guide-Activities)[North Central Florida Car Rentals](https://expedia.ca/Car-Rentals-In-North-Central-Florida.d6233773.Car-Rental-Guide)[North Central Florida Vacation Packages](https://expedia.ca/North-Central-Florida.d6233773.Destination-Travel-Guides) ![Gainesville featuring modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/61000/61913-Gainesville.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in North Central Florida, FL - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on North Central Florida Luxury Hotels Tonight [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-11-01&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-11-02&endDate=2025-11-03&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6233773&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top North Central Florida Luxury Hotels ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/2aec1127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/2eb44850.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/68797221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/19000/18915/147eb861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont By Wyndham Gainesville I-75 Gainesville 5.4/10 (1000) "Stay at your own risk" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lance CA $88 CA $114 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Gainesville-Hotels-Baymont-By-Wyndham-Gainesville.h18915.Hotel-Information) ![Premium bedding, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/c251e287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/62d30ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Living room](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/d6f46a2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/cd217d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palms Garden Inn Lake City 7.4/10 Good (570) "Nice clean room with a big bed Good AC" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mike horne CA $91 CA $102 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Lake-City-Hotels-Palms-Garden-Inn.h40753.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/1bfc5692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/ad8fe69d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/8ce5f9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/fddc9a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Lake City Lake City 8.8/10 Excellent (1001) "Reasonably priced, nice and clean, easy access to I 75" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dianne CA $99 CA $112 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Lake-City-Hotels-Americas-Best-Value-Inn-Lake-City.h1039754.Hotel-Information) ![Soundproofing, bed sheets](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/bf712c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/0453d1b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/6d118001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9730000/9724400/9724310/eb197530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Driftwood Inn Lake City 7.8/10 Good (747) "The stay and property was okay. The smell in the room was terrible. It smelled like cigarettes which made it had to sleep, but you get what you pay for." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emmanuel [](https://www.expedia.ca/Lake-City-Hotels-Driftwood-Inn.h9724310.Hotel-Information) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/d3372ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/ab5ce2f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/65c924d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/62b4db64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Gainesville University I-75 Gainesville 5.6/10 (1003) "This property was the worst hotel that I’ve ever stayed in. It was nasty. There’s absolutely nothing good to say about it. Do not stay here. There was literally a girl in a thong and a bra when we got off the elevator just standing there. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $94 CA $106 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Gainesville-Hotels-Days-Inn-By-Wyndham-Gainesville-University-I-75.h19555.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/0450f0b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/8fcede96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, 1 Double Bed, Kitchen](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/e8072106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3780000/3779400/3779376/89c63699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Gainesville I-75 Gainesville 6.2/10 (1006) "Decent hotel at best. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cody CA $96 CA $109 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Gainesville-Hotels-WoodSpring-Suites-Gainesville-I-75.h3779376.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/a1a33286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/8cb7bb5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/cecd35c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/9d1d7d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Waldo Inn and Suites Waldo 8.8/10 Excellent (935) "Very clean pet friendly hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald CA $119 CA $134 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) ![Deluxe Double Room](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/8b34842e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/581111fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/1827e91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/6e19cc8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gainesville Lodge Gainesville 7.4/10 Good (548) "Very easy remote check in, room was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert [](https://www.expedia.ca/Gainesville-Hotels-Gainesville-Lodge.h9724836.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/7dbdcf15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/58180c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/w3839h2551x0y3-310d80bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/50a7bef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton University of Florida Conference Center Gainesville Gainesville 8.4/10 Very good (1007) "Best hotel in Gainesville- great staff and service and amazing location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy CA $136 CA $154 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Gainesville-Hotels-Hilton-University-Of-Florida-Conference-Center-Gainesville.h475205.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1210da70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1c3421f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/2c633ddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/5c4d5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Gainesville I-75 Hospital University Area Gainesville 7.2/10 Good (1012) "The Staff was so Helpful and professional and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica CA $70 CA $79 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=6233773&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top North Central Florida Hotel Reviews ![Comfort Inn University](//images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85_y.jpg) ### Comfort Inn University 10/10 Excellent "Parking good. Room clean. Breakfast was ok. Check-in friendly. " [](https://expedia.ca/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ![Red Roof Inn PLUS+ Gainesville](//images.trvl-media.com/lodging/1000000/90000/82700/82677/5b4e3b0e_y.jpg) ### Red Roof Inn PLUS+ Gainesville 10/10 Excellent "Very clean nice room" [](https://expedia.ca/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information) ![Country Inn & Suites by Radisson, Gainesville, FL](//images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/8584a629_y.jpg) ### Country Inn & Suites by Radisson, Gainesville, FL 10/10 Excellent "Very nice front desk stagf" [](https://expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![Hilton Garden Inn Gainesville](//images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/1560249f_y.jpg) ### Hilton Garden Inn Gainesville 10/10 Excellent "Room was so clean and comfortable. Easy check in, accommodating and kind staff. " [](https://expedia.ca/Gainesville-Hotels-Hilton-Garden-Inn-Gainesville.h1631322.Hotel-Information) ![Sleep Inn & Suites University/Shands](//images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg) ### Sleep Inn & Suites University/Shands 10/10 Excellent "Friendly efficient staff, comfortable clean room, good location near college & have shuttle to game. Definitely would stay here again " [](https://expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Days Inn by Wyndham Ocala North](//images.trvl-media.com/lodging/1000000/10000/900/818/ffb5d22e_y.jpg) ### Days Inn by Wyndham Ocala North 10/10 Excellent "Parking area well lilt and the property was quite." [](https://expedia.ca/Ocala-Hotels-Days-Inn-By-Wyndham-Ocala-North.h818.Hotel-Information) ![DoubleTree by Hilton Gainesville](//images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg) ### DoubleTree by Hilton Gainesville 10/10 Excellent "The bathroom towels smell funny , only that be noted but the rest perfect thanks " [](https://expedia.ca/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![Red Roof Inn Ocala](//images.trvl-media.com/lodging/1000000/890000/889600/889568/0d7e45b2_y.jpg) ### Red Roof Inn Ocala 10/10 Excellent "The only issue was the AC was leaking, which could cause somebody to get electrocuted" [](https://expedia.ca/Ocala-Hotels-Red-Roof-Inn-Ocala.h889568.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - More ways to book - [Green Hotels in Daytona Beach](https://www.expedia.ca/Daytona-Beach-Hotels-Green-Sustainable.0-0-d6023995-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts and in Daytona Beach](https://www.expedia.ca/Daytona-Beach-Hotels-Honeymoon-Hotels.0-0-d6023995-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - 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