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Our top choices for Buffalo hotels

A modern hotel lobby with a coffee station, seating area, and a large screen.
A hotel entrance with a clear view of the greenery outside, a doormat with the hotel name, and emergency instructions on the glass doors.
A reception area with a brick counter, a framed certificate on the wall, and a sign indicating hotel ownership.
A hotel room with two beds, each with a headboard and a lamp.

1. Quality Inn Union US Hwy 176

Quality Inn Union US Hwy 176
Union
United States
Mary
CA $120
CA $133 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Union US Hwy 176
A hotel room with a bed, a sofa, a nightstand, and a small table.
A reception area with a blue wall, a wooden counter, a glass door leading outside, and a potted plant.
A rectangular pool with a blue border, surrounded by a black fence. There are lounge chairs and a small table with chairs along the poolside.
A row of residential buildings with a blue door, a white window, and a vent on the wall.

2. Rodeway Inn Union

Rodeway Inn Union
Union
United States
Dejuana
CA $91
CA $99 total
includes taxes & fees
Nov 3 - Nov 4
Rodeway Inn Union
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A building with a sign for "The Night Inn" featuring a stylized 'N' logo.
A reception area with a counter, seating, a clock, and a sign for 'The Night'.
A hotel room with a wooden table, a black office chair, a black refrigerator, and a large mirror on the wall.

3. The Night Inn

The Night Inn
Union
United States
Robert
CA $93
CA $109 total
includes taxes & fees
Oct 13 - Oct 14
The Night Inn
A hotel with a central entrance, multiple floors, and a flag display.
A breakfast buffet with various food items, coffee machines, and a toaster.
A hotel room with a desk, chair, bed, and a bathroom with a sink and mirror.
A hotel reception area with a modern reception desk, seating area, and large windows.

4. Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College
Clinton
United States
alberto
CA $128
CA $148 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Suites Clinton near Presbyterian College
A breakfast area with a coffee station, a sign indicating breakfast starts here, and a wall with framed artwork.
A Hampton Inn & Suites hotel with a modern facade, a welcoming entrance, and a landscaped front yard.
A compact living space with a kitchenette, a blue sofa, and a window with curtains.
A gym with treadmills, weight machines, and a mirror reflecting the space.

5. Hampton Inn & Suites Clinton - I-26

Hampton Inn & Suites Clinton - I-26
Clinton
United States
Andrea
CA $188
CA $210 total
includes taxes & fees
Nov 11 - Nov 12
Hampton Inn & Suites Clinton - I-26
A modern lobby with a reception desk, seating area, and a television screen.
A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.
A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.
A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

6. Best Western Spartanburg I-26

Best Western Spartanburg I-26
Spartanburg
United States
Santhosh
CA $132
CA $147 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Spartanburg I-26
A modern living room with a sofa, armchairs, a patterned rug, and a Buddha statue.
A swimming pool with a lifeguard chair, a shallow water sign, and a no diving allowed sign.
A conference room with tables and chairs, a television, and a whiteboard.
A laundry room with a washing machine, dryer, chair, and table.

7. Days Inn by Wyndham Clinton / Laurens I-26

Days Inn by Wyndham Clinton / Laurens I-26
Clinton
United States
Julian
CA $96
CA $108 total
includes taxes & fees
Oct 18 - Oct 19
Days Inn by Wyndham Clinton / Laurens I-26
A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.
An indoor swimming pool with clear water, a blue border, and a lifeguard station. There are lounge chairs and a covered seating area.
A Holiday Inn Express hotel with a covered entrance, brick facade, and large windows.
A hotel room with a kitchenette, two beds, a red sofa, and a dining area.

8. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Spartanburg
United States
Amy
CA $150
CA $166 total
includes taxes & fees
Oct 31 - Nov 1
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
An outdoor seating area with sofas, a fire pit, and string lights.
A modern interior with hanging chairs, tables, and a view of the parking lot.
A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.
A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

9. Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
Spartanburg
United States
Anthony
CA $151
CA $167 total
includes taxes & fees
Nov 1 - Nov 2
Tru by Hilton Spartanburg
A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.
A modern kitchen with marble countertops, wooden shelves, and a wine station.
A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.
A lobby with a stone fireplace, sofas, a TV mounted on the wall, and a bar area in the background.

10. Spartanburg Marriott

Spartanburg Marriott
Spartanburg
United States
Daniel
CA $168
CA $187 total
includes taxes & fees
Oct 25 - Oct 26
Spartanburg Marriott
A hotel room with two beds, a desk, a bathroom, and a TV.
A modern hotel lobby with a seating area, a dining space, and a reception desk.
A restaurant with multiple tables and chairs, a kitchen area, and a wall with food images.
A modern hotel with a covered entrance, multiple balconies, and a parking area.

11. Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26
Clinton
United States
Tyiesha
CA $113
CA $131 total
includes taxes & fees
Oct 13 - Oct 14
Quality Inn Clinton - Laurens I-26
A bar area with a long counter, multiple stools, and shelves stocked with bottles.
A restaurant with a central island seating area, multiple tables, and a large mural on the wall.
A spacious lobby with a bar area, seating, and large windows.
A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.

12. Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg
Spartanburg
United States
Yuliya
CA $175
CA $194 total
includes taxes & fees
Nov 1 - Nov 2
Hilton Garden Inn Spartanburg
A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.
A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.
A modern living room with a dark-colored sofa, armchairs, a coffee table, and a bookshelf filled with decorative items.
A swimming pool with steps leading up to a building entrance, surrounded by lounge chairs and umbrellas.

13. AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
Spartanburg
United States
Willow
CA $227
CA $252 total
includes taxes & fees
Oct 18 - Oct 19
AC Hotel by Marriott Spartanburg
A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.
A modern lobby with blue sofas, a reception desk, and a glass coffee table.
A hotel room with a desk, office chair, sofa, and a large wall art piece.
A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

14. Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
Spartanburg
United States
Willie
CA $130
CA $144 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Suites At WestGate Mall
A modern living room with a stone accent wall, a flat-screen TV, and a blue abstract rug.
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A modern lobby with a sofa, armchairs, and a coffee table. There is a reception desk and a dining area in the background.
A modern hotel with a prominent Fairfield sign, multiple floors, and a well-lit entrance.

15. Fairfield by Marriott Inn & Suites Spartanburg Downtown

Fairfield by Marriott Inn & Suites Spartanburg Downtown
Spartanburg
United States
Zachary
CA $187
CA $207 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield by Marriott Inn & Suites Spartanburg Downtown
A modern kitchen with a central island, bar stools, and pendant lighting.
A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.
A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.
A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

16. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Spartanburg
United States
Melinda
CA $162
CA $180 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
A hotel reception area with a red sign indicating free Wi-Fi in all rooms, a control panel, a laptop, and a payment terminal.
A hotel with a red sign reading 'Red Roof Inn & Suites' and a two-story structure with multiple windows and balconies.
A hotel room with two beds, a bathroom, and a hallway.
A vending machine with snacks and a drink dispenser.

17. Red Roof Inn Spartanburg - I-85

Red Roof Inn Spartanburg - I-85
Spartanburg
United States
Walker
CA $83
CA $93 total
includes taxes & fees
Oct 19 - Oct 20
Red Roof Inn Spartanburg - I-85
A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.
A food service counter with a sign that reads "EXPRESS START".
A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.
A hotel reception area with a wooden reception desk, a receptionist, and a revolving door.

18. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Spartanburg
United States
Nephie
CA $163
CA $180 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
A dining area with tables and chairs, a television mounted on the wall, and a kitchen area with appliances.
A hotel lobby with a reception desk, seating area, and a television.
A hotel room with a bed, a desk with a computer, a chair, a lamp, and a view of the outdoors through a window.
A Rodeway Inn with a two-story building, a parking lot, and a few cars parked in front.

19. Rodeway Inn Laurens

Rodeway Inn Laurens
Laurens
United States
Ellamae
CA $99
CA $111 total
includes taxes & fees
Nov 3 - Nov 4
Rodeway Inn Laurens
A hotel room with a bed, a desk with a computer, a television, and a microwave.
A single-story motel with a flat roof, large windows, and a small porch area.
A room with two beds, each with a wooden headboard and a floral bedspread. There is a small wooden table beside the beds.
A bathroom with a bathtub, shower curtain, and marble wall tiles.

20. SUN AND SAND MOTEL

SUN AND SAND MOTEL
Spartanburg
United States
Jeffrey
CA $84
CA $94 total
includes taxes & fees
Nov 1 - Nov 2
SUN AND SAND MOTEL
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Top Buffalo Hotel Reviews

Fairfield by Marriott Inn & Suites Spartanburg Downtown

Fairfield by Marriott Inn & Suites Spartanburg Downtown

10/10 Excellent
"Very hospitable, amazing service, clean room"
Emma 1-night trip
Posted 6 hours ago
Fairfield by Marriott Inn & Suites Spartanburg Downtown
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

8/10 Good
"Out side had trash everywhere"
Bruce 2-night trip
Posted 7 hours ago
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Best Western Spartanburg I-26

Best Western Spartanburg I-26

10/10 Excellent
"Super place. We’ll be back!"
Arch 1-night trip
Posted 1 day ago
Best Western Spartanburg I-26
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

10/10 Excellent
"Just all around exceptional ! Will stay again when ever I pass through!"
Mary 1-night trip
Posted 1 day ago
Hilton Garden Inn Spartanburg
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

10/10 Excellent
"Parking some times hard with all the truck try to finding spots"
rose 8-night trip
Posted 2 days ago
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College

10/10 Excellent
"x"
KARL 2-night trip
Posted 3 days ago
Comfort Suites Clinton near Presbyterian College
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

10/10 Excellent
"The front desk staff was exceptionally pleasant. The hotel was clean and smelled amazing. Very comfortable and relaxing. Breakfast was good! Had a great stay and we will be back!"
aprelle 1-night trip
Posted 8 days ago
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

More cheap stays in Buffalo

Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

501 South Blackstock Rd Spartanburg SC
CA $106
CA $118 total
Nov 8 - Nov 9
includes taxes & fees
Sleep Inn Spartanburg Southwest
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

458 West Blackstock Road Spartanburg SC
CA $130
CA $144 total
Nov 8 - Nov 9
includes taxes & fees
Comfort Suites At WestGate Mall
Best Western Spartanburg I-26

Best Western Spartanburg I-26

488 South Blackstock Road Spartanburg SC
CA $132
CA $147 total
Nov 1 - Nov 2
includes taxes & fees
9.2/10 Wonderful! (67 reviews)
Best Western Spartanburg I-26
Comfort Suites Clinton near Presbyterian College

Comfort Suites Clinton near Presbyterian College

12865 Hwy 56 N Clinton SC
CA $128
CA $148 total
Nov 1 - Nov 2
includes taxes & fees
8/10 Very good! (818 reviews)
Comfort Suites Clinton near Presbyterian College
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

103 Franklin Avenue Spartanburg SC
CA $151
CA $167 total
Nov 1 - Nov 2
includes taxes & fees
Tru by Hilton Spartanburg
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Ln Spartanburg SC
CA $163
CA $180 total
Oct 25 - Oct 26
includes taxes & fees
8.6/10 Excellent! (1,007 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Hotels in Buffalo with star rating

Frequently asked questions

What is the best area to stay in Buffalo?
The best area to stay in Buffalo, South Carolina, is near the intersection of Main Street and South Carolina Highway 215, as this is the most developed part of the town.This central area offers the most convenience for visitors. You'll find the Buffalo Post Office and a few local shops and eateries clustered around this junction. It's a small, rural community, and this intersection serves as its commercial heart.For solo travellers or couples looking for a quiet retreat, staying in this area provides easy access to the local amenities and a sense of the community.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Buffalo.
How much is the nightly rate at a Buffalo hotel?
Prices for hotels in Buffalo often vary, but you can find a great deal from CA $93 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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