Title: Book the Best Anna SPA Resorts from CA $146 - Spa Hotels in Anna, IL | Expedia.ca [Hotels in Anna](https://expedia.ca/Anna-Hotels.d6406.Travel-Guide-Hotels)[Vacation Rentals in Anna](https://expedia.ca/Anna-Vacation-Rentals.d6406.Travel-Guide-VacationRentals)[Anna Car Rentals](https://expedia.ca/Car-Rentals-In-Anna.d6406.Car-Rental-Guide)[Anna Vacation Packages](https://expedia.ca/Anna.d6406.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/pool.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/pool.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Anna Spa Hotels Tonight [Feb 14 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2026-02-14&endDate=2026-02-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 15 - Feb 16](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2026-02-15&endDate=2026-02-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2026-02-20&endDate=2026-02-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2026-02-27&endDate=2026-03-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Anna hotels with a spa ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/182edc95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature)](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,001 reviews) "Breakfast was very good and staff was extremely friendly and rooms were very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rex CA $129 CA $146 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-28&endDate=2026-03-01®ionId=6406&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Anna Pool Breakfast included Hot tub 4 stars 5 stars ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AFFINITY_SPRING_PROMO_6406) ## Top Anna Hotel Reviews ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "The staff was ver accommodating love the remodel stayed 4 days could have stayed 4 more. staff is always heplful and friendly 5 \*\*\*\*\*. One issue. Its been 10 since i checked out, have not got the $50 deposit bk into my account. Thank You I will be coming bk soon" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg) ### Drury Inn & Suites Marion 10/10 Excellent "Very clean. Great social hour and breakfast. Staff was very friendly and welcoming. " [](https://expedia.ca/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The room was great. The facility was excellent. The people were excellent. Definitely going back." [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Best Western Marion Hotel](https://images.trvl-media.com/lodging/1000000/100000/98000/97975/86964c5d_y.jpg) ### Best Western Marion Hotel 10/10 Excellent "clean room, great service, and breakfast was good (biscuits and gravy, sausage, and eggs). Night-time staff was excellent, very nice, accommodating, and made the check in process painless. Would recommend to anyone travelling to stay here. " [](https://expedia.ca/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Anna? ### What's there to see and do in Anna? ### What is a Anna spa hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in West Vienna ](https://www.expedia.ca/3Star-West-Vienna-Hotels.s30-0-d553248635975864465.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Pomona ](https://www.expedia.ca/5Star-Pomona-Hotels.s50-0-d553248635592817265.Travel-Guide-Filter-Hotels) - [Apartments in Alto Pass ](https://www.expedia.ca/Alto-Pass-Apartments.d73449-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Alto Pass ](https://www.expedia.ca/Alto-Pass-Cabins.d73449-aaCabins.Travel-Guide-Accommodation) - [Alto Pass Hotels ](https://www.expedia.ca/Alto-Pass-Hotels.d73449.Travel-Guide-Hotels) - [Resorts in Alto Pass ](https://www.expedia.ca/Alto-Pass-Resort-Hotels.d73449-aaResortHotels.Travel-Guide-Accommodation) - [Belknap Hotels ](https://www.expedia.ca/Belknap-Hotels.d3000346121.Travel-Guide-Hotels) - [Cheap Hotels in Bloomfield ](https://www.expedia.ca/Bloomfield-Hotels-Cheap-Hotels.0-0-d553248635975848050-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Bloomfield ](https://www.expedia.ca/Bloomfield-Hotels-Luxury-Hotel.0-0-d553248635975848050-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Hotels near Blue Sky Vineyards ](https://www.expedia.ca/Blue-Sky-Vineyards-Hotels.0-l553248621532655803-0.Travel-Guide-Filter-Hotels) - [B&B in Carbondale ](https://www.expedia.ca/Carbondale-Bed-And-Breakfast.d2248-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Adults Only Resorts & in Carbondale ](https://www.expedia.ca/Carbondale-Hotels-Adults-Only-Resorts.0-0-d2248-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Carbondale ](https://www.expedia.ca/Carbondale-Hotels-Cheap-Hotels.0-0-d2248-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Carbondale ](https://www.expedia.ca/Carbondale-Hotels-Hotel-With-Pool.0-0-d2248-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Carbondale ](https://www.expedia.ca/Carbondale-Hotels-Hotels-With-Free-Breakfast.0-0-d2248-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Carbondale ](https://www.expedia.ca/Carbondale-Hotels-Hotels-With-Kitchenettes.0-0-d2248-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Carbondale ](https://www.expedia.ca/Carbondale-Hotels-Luxury-Hotel.0-0-d2248-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Carbondale Hotels ](https://www.expedia.ca/Carbondale-Hotels.d2248.Travel-Guide-Hotels) - [Resorts in Carbondale ](https://www.expedia.ca/Carbondale-Resort-Hotels.d2248-aaResortHotels.Travel-Guide-Accommodation) - [Hotels near Carbondale Station ](https://www.expedia.ca/Carbondale-Station-Hotels.d6194368.Travel-Guide-Hotels) - [Cheap Hotels in Carterville ](https://www.expedia.ca/Carterville-Hotels-Cheap-Hotels.0-0-d6283910-tCheapHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Carterville ](https://www.expedia.ca/Carterville-Hotels-Pet-Friendly-Hotel.0-0-d6283910-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [B&B in Cobden ](https://www.expedia.ca/Cobden-Bed-And-Breakfast.d3000433811-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Chalets in Cobden ](https://www.expedia.ca/Cobden-Chalets.d3000433811-aaChalets.Travel-Guide-Accommodation) - [Family Hotels in Cobden ](https://www.expedia.ca/Cobden-Hotels-Family-Hotel.0-0-d3000433811-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Cobden ](https://www.expedia.ca/Cobden-Hotels-Hotel-With-Pool.0-0-d3000433811-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Cobden ](https://www.expedia.ca/Cobden-Hotels-Hotels-With-Hot-Tubs.0-0-d3000433811-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Cobden ](https://www.expedia.ca/Cobden-Hotels-Luxury-Hotel.0-0-d3000433811-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Cobden ](https://www.expedia.ca/Cobden-Hotels-Waterpark-Hotels.0-0-d3000433811-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in Cobden ](https://www.expedia.ca/Cobden-Hotels-Winery-Hotel.0-0-d3000433811-tWineryHotel.Travel-Guide-Filter-Hotels) - [Cobden Hotels ](https://www.expedia.ca/Cobden-Hotels.d3000433811.Travel-Guide-Hotels) - [Lodges in Cobden ](https://www.expedia.ca/Cobden-Lodges.d3000433811-aaLodges.Travel-Guide-Accommodation) - [Motels in Cobden ](https://www.expedia.ca/Cobden-Motels.d3000433811-aaMotels.Travel-Guide-Accommodation) - [Resorts in Cobden ](https://www.expedia.ca/Cobden-Resort-Hotels.d3000433811-aaResortHotels.Travel-Guide-Accommodation) - [B&B in Dongola ](https://www.expedia.ca/Dongola-Bed-And-Breakfast.d3000346219-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Dongola ](https://www.expedia.ca/Dongola-Guest-Houses.d3000346219-aaGuestHouses.Travel-Guide-Accommodation) - [Dongola Hotels ](https://www.expedia.ca/Dongola-Hotels.d3000346219.Travel-Guide-Hotels) - [Motels in Dongola ](https://www.expedia.ca/Dongola-Motels.d3000346219-aaMotels.Travel-Guide-Accommodation) - [Hotels near Ferne Clyffe State Park ](https://www.expedia.ca/Ferne-Clyffe-State-Park-Hotels.0-l553248635944111208-0.Travel-Guide-Filter-Hotels) - [Hotels near Giant City State Park ](https://www.expedia.ca/Giant-City-State-Park-Hotels.0-l553248621532655802-0.Travel-Guide-Filter-Hotels) - [Farmstay in Goreville ](https://www.expedia.ca/Goreville-Agritourism.d3000434209-aaAgritourism.Travel-Guide-Accommodation) - [Chalets in Goreville ](https://www.expedia.ca/Goreville-Chalets.d3000434209-aaChalets.Travel-Guide-Accommodation) - [Luxury Hotels in Goreville ](https://www.expedia.ca/Goreville-Hotels-Luxury-Hotel.0-0-d3000434209-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Goreville Hotels ](https://www.expedia.ca/Goreville-Hotels.d3000434209.Travel-Guide-Hotels) - [Luxury Hotels in Grand Chain ](https://www.expedia.ca/Grand-Chain-Hotels-Luxury-Hotel.0-0-d3000434218-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Grand Chain Hotels ](https://www.expedia.ca/Grand-Chain-Hotels.d3000434218.Travel-Guide-Hotels) - [Lodges in Grand Chain ](https://www.expedia.ca/Grand-Chain-Lodges.d3000434218-aaLodges.Travel-Guide-Accommodation) - [Lodges in Grand Tower ](https://www.expedia.ca/Grand-Tower-Lodges.d553248634983520694-aaLodges.Travel-Guide-Accommodation) - [Jonesboro Hotels ](https://www.expedia.ca/Jonesboro-Hotels.d3000434361.Travel-Guide-Hotels) - [Motels in Jonesboro ](https://www.expedia.ca/Jonesboro-Motels.d3000434361-aaMotels.Travel-Guide-Accommodation) - [Karnak Hotels ](https://www.expedia.ca/Karnak-Hotels.d3000346358.Travel-Guide-Hotels) - [Aparthotels in Makanda ](https://www.expedia.ca/Makanda-Apart-Hotels.d129194-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Makanda ](https://www.expedia.ca/Makanda-Bed-And-Breakfast.d129194-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Luxury Hotels in Makanda ](https://www.expedia.ca/Makanda-Hotels-Luxury-Hotel.0-0-d129194-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Makanda Hotels ](https://www.expedia.ca/Makanda-Hotels.d129194.Travel-Guide-Hotels) - [Resorts in Makanda ](https://www.expedia.ca/Makanda-Resort-Hotels.d129194-aaResortHotels.Travel-Guide-Accommodation) - [Cheap Hotels in McClure ](https://www.expedia.ca/McClure-Hotels-Cheap-Hotels.0-0-d553248634983484559-tCheapHotels.Travel-Guide-Filter-Hotels) - [Rv Parks in McClure ](https://www.expedia.ca/McClure-RV-Parks.d553248634983484559-aaRVParks.Travel-Guide-Accommodation) - [Cheap Hotels in Mounds ](https://www.expedia.ca/Mounds-Hotels-Cheap-Hotels.0-0-d553248634983401107-tCheapHotels.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Murphysboro ](https://www.expedia.ca/Murphysboro-Hotels-Cheap-Hotels.0-0-d55857-tCheapHotels.Travel-Guide-Filter-Hotels) - [Farmstay in Pomona ](https://www.expedia.ca/Pomona-Agritourism.d553248635592817265-aaAgritourism.Travel-Guide-Accommodation) - [Pomona Hotels ](https://www.expedia.ca/Pomona-Hotels.d553248635592817265.Travel-Guide-Hotels) - [Pulaski Hotels ](https://www.expedia.ca/Pulaski-Hotels.d553248634983234866.Travel-Guide-Hotels) - [Pulleys Mill Hotels ](https://www.expedia.ca/Pulleys-Mill-Hotels.d553248635975872309.Travel-Guide-Hotels) - [Hotels near Southern Illinois University ](https://www.expedia.ca/Southern-Illinois-University-Hotels.0-l6091413-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Tamms ](https://www.expedia.ca/Tamms-Hotels-Luxury-Hotel.0-0-d3000346607-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Tamms Hotels ](https://www.expedia.ca/Tamms-Hotels.d3000346607.Travel-Guide-Hotels) - [Aparthotels in Ullin ](https://www.expedia.ca/Ullin-Apart-Hotels.d168251-aaApartHotels.Travel-Guide-Accommodation) - [Guest Houses in Ullin ](https://www.expedia.ca/Ullin-Guest-Houses.d168251-aaGuestHouses.Travel-Guide-Accommodation) - [Hotels & Resorts for Couples in Ullin ](https://www.expedia.ca/Ullin-Hotels-Couples-Resorts-Hotels.0-0-d168251-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Ullin ](https://www.expedia.ca/Ullin-Hotels-Golf-Hotel.0-0-d168251-tGolfHotel.Travel-Guide-Filter-Hotels) - [Ullin Hotels ](https://www.expedia.ca/Ullin-Hotels.d168251.Travel-Guide-Hotels) - [Villas in Ullin ](https://www.expedia.ca/Ullin-Villas.d168251-aaVillas.Travel-Guide-Accommodation) - [Cheap Hotels in Vienna ](https://www.expedia.ca/Vienna-Hotels-Cheap-Hotels.0-0-d56022-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Vienna ](https://www.expedia.ca/Vienna-Hotels-Golf-Hotel.0-0-d56022-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Vienna ](https://www.expedia.ca/Vienna-Hotels-Hotel-With-Pool.0-0-d56022-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Vienna ](https://www.expedia.ca/Vienna-Hotels-Hotels-With-Indoor-Pool.0-0-d56022-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [B&B in Wolf Creek ](https://www.expedia.ca/Wolf-Creek-Bed-And-Breakfast.d553248635544019054-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Wolf Creek ](https://www.expedia.ca/Wolf-Creek-Cabins.d553248635544019054-aaCabins.Travel-Guide-Accommodation) - [Chalets in Wolf Creek ](https://www.expedia.ca/Wolf-Creek-Chalets.d553248635544019054-aaChalets.Travel-Guide-Accommodation) - [Hotels with a Pool in Wolf Creek ](https://www.expedia.ca/Wolf-Creek-Hotels-Hotel-With-Pool.0-0-d553248635544019054-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Lodges in Wolf Creek ](https://www.expedia.ca/Wolf-Creek-Lodges.d553248635544019054-aaLodges.Travel-Guide-Accommodation) - [Motels in Wolf Creek ](https://www.expedia.ca/Wolf-Creek-Motels.d553248635544019054-aaMotels.Travel-Guide-Accommodation) - [Resorts in Wolf Creek ](https://www.expedia.ca/Wolf-Creek-Resort-Hotels.d553248635544019054-aaResortHotels.Travel-Guide-Accommodation) - [Flights to Carbondale ](https://www.expedia.ca/Cheap-Flights-To-Carbondale.d2248.Travel-Guide-Flights) - [Flights to Ullin ](https://www.expedia.ca/Cheap-Flights-To-Ullin.d168251.Travel-Guide-Flights) - [Flights from Carbondale ](https://www.expedia.ca/lp/flights/2248/flights-from-carbondale) - [Flights from Cobden ](https://www.expedia.ca/lp/flights/3000433811/flights-from-cobden) - [Flights from Goreville ](https://www.expedia.ca/lp/flights/3000434209/flights-from-goreville) - [Flights from Cypress ](https://www.expedia.ca/lp/flights/553248634983556233/flights-from-cypress) - [Flights from Alto Pass ](https://www.expedia.ca/lp/flights/73449/flights-from-alto-pass) - [Visit Cobden ](https://www.expedia.ca/Cobden.dx3000433811) - [Visit Jonesboro ](https://www.expedia.ca/Jonesboro.dx3000434361) - [Makanda Vacations ](https://www.expedia.ca/Makanda.d129194.Destination-Travel-Guides) - [Visit Pulaski County ](https://www.expedia.ca/Pulaski-County.dx553248635976433096) - [Shawnee Community College ](https://www.expedia.ca/Shawnee-Community-College-Anna.d6183446.Vacation-Attraction) - [Avis Rental Cars in Goreville ](https://www.expedia.ca/Avis-Car-Rentals-In-Goreville.d3000434209-c41.Car-Rental-Guide-Suppliers) - [Car rental Carbondale ](https://www.expedia.ca/Car-Rentals-In-Carbondale.d2248.Car-Rental-Guide) - [Car rental Cobden ](https://www.expedia.ca/Car-Rentals-In-Cobden.d3000433811.Car-Rental-Guide) - [Hertz Rental Cars in Carbondale ](https://www.expedia.ca/Hertz-Car-Rentals-In-Carbondale.d2248-c40.Car-Rental-Guide-Suppliers) - [Book Spa Hotels in Anna on Expedia.com ](https://www.expedia.com/Anna-Hotels-Spa-Hotel.0-0-d6406-tSpaHotel.Travel-Guide-Filter-Hotels)