Title: 5 Stars Hotels in Niagara Wine Region, Niagara-on-the-Lake from CA $146 - Find Cheap Niagara Wine Region Hotels With 5 Stars | Expedia.ca [Niagara Wine Region Travel Guide](https://expedia.ca/Niagara-Wine-Region.dx6186545)[Hotels in Niagara Wine Region](https://expedia.ca/Niagara-Wine-Region-Hotels.d6186545.Travel-Guide-Hotels)[Vacation Rentals in Niagara Wine Region](https://expedia.ca/Niagara-Wine-Region-Vacation-Rentals.d6186545.Travel-Guide-VacationRentals)[Flights to Niagara Wine Region](https://expedia.ca/Cheap-Flights-To-Niagara-Wine-Region.d6186545.Travel-Guide-Flights)[Niagara Wine Region Car Rentals](https://expedia.ca/Car-Rentals-In-Niagara-Wine-Region.d6186545.Car-Rental-Guide)[Niagara Wine Region Vacation Packages](https://expedia.ca/Niagara-Wine-Region.d6186545.Destination-Travel-Guides) ![Niagara-on-the-Lake showing landscape views and heritage architecture](https://images.trvl-media.com/place/8957/6c99dba4-89db-4bee-aa64-d81630a4712a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Niagara Wine Region, Niagara-on-the-Lake from CA $146 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Niagara Wine Region 5 Star Hotels Tonight [Nov 25 - Nov 26](https://www.expedia.ca/Hotel-Search?regionId=6186545&startDate=2025-11-25&endDate=2025-11-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 26 - Nov 27](https://www.expedia.ca/Hotel-Search?regionId=6186545&startDate=2025-11-26&endDate=2025-11-27&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6186545&startDate=2025-11-28&endDate=2025-11-30&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6186545&startDate=2025-12-05&endDate=2025-12-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Niagara Wine Region 5 Star Hotels ![1 bedroom, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/1000000/450000/444600/444572/48d54ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/450000/444600/444572/4c72b7a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/450000/444600/444572/1a0bdc92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444600/444572/8390df10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White Oaks Resort & Spa Glendale 9.6/10 Exceptional (2247) "Great spot, friendly staff and good location.. meets all the points!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Geoffrey CA $170 CA $217 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Niagara-Falls-Hotels-White-Oaks-Resort-Spa.h444572.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Niagara-Wine-Region-Hotels.s50-0-d6186545.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Niagara-Wine-Region-Hotels.s50-0-d6186545.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Niagara Wine Region. ![Wyndham Grand Fallsview Hotel](https://images.trvl-media.com/lodging/1000000/10000/6300/6226/cd163145_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Wyndham Grand Fallsview Hotel 6455 Fallsview Blvd Niagara Falls ON CA $110 CA $146 total Nov 30 - Dec 1 includes taxes & fees 8/10 Very Good! (5,105 reviews) [](https://expedia.ca/Niagara-Falls-Hotels-Four-Points-By-Sheraton-Niagara-Falls-Fallsview.h6226.Hotel-Information) ![Hilton Niagara Falls/Fallsview Hotel & Suites](https://images.trvl-media.com/lodging/1000000/470000/463200/463153/242dc0c0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Niagara Falls/Fallsview Hotel & Suites 6361 Fallsview Blvd Niagara Falls ON CA $152 CA $198 total Nov 26 - Nov 27 includes taxes & fees 7.8/10 Good! (12,819 reviews) [](https://expedia.ca/Niagara-Falls-Hotels-Hilton-Niagara-FallsFallsview-Hotel-Suites.h463153.Hotel-Information) ![Marriott Niagara Falls Fallsview Hotel & Spa](https://images.trvl-media.com/lodging/1000000/130000/120200/120155/4844e098_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Marriott Niagara Falls Fallsview Hotel & Spa 6740 Fallsview Blvd Niagara Falls ON CA $170 CA $243 total Dec 2 - Dec 3 includes taxes & fees 8.4/10 Very Good! (3,586 reviews) [](https://expedia.ca/Niagara-Falls-Hotels-Marriott-Niagara-Falls-Fallsview-Hotel-Spa.h120155.Hotel-Information) Still don't see what you're looking for? [See all properties in Niagara Wine Region.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F11%2F2025&endDate=27%2F11%2F2025®ionId=6186545&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F11%2F2025&endDate=27%2F11%2F2025®ionId=6186545&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F11%2F2025&endDate=27%2F11%2F2025®ionId=6186545&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F11%2F2025&endDate=27%2F11%2F2025®ionId=6186545&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F11%2F2025&endDate=27%2F11%2F2025®ionId=6186545&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F11%2F2025&endDate=27%2F11%2F2025®ionId=6186545&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Niagara Wine Region Wineries, lake views, and sights from Jackson-Triggs Winery to Peller Estates Winery—discover it all in Niagara Wine Region. [See all hotels in Niagara Wine Region](https://www.expedia.ca/Hotel-Search?startDate=2025-12-09&endDate=2025-12-10&adults=2®ionId=6186545) ![Niagara-on-the-Lake showing landscape views and heritage architecture](https://images.trvl-media.com/place/8957/6c99dba4-89db-4bee-aa64-d81630a4712a.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Niagara Wine Region Hotel Reviews ## Find out more about Niagara Wine Region ## Five Star Hotels in Niagara Wine Region There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Niagara Wine Region so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Niagara Wine Region and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Niagara Wine Region Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Niagara Wine Region The results are in, and Niagara Wine Region 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Niagara Wine Region! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Niagara Wine Region today and settle down in the lap of luxury tomorrow. ## Explore a world of travel with Expedia - Flights - Packages - Cars - Other - [Flights to Toronto](https://www.expedia.ca/Cheap-Flights-To-Toronto.d178314.Travel-Guide-Flights) - [Flights from Niagara District](https://www.expedia.ca/lp/airports/ycm/flights-from-niagara-district-airport) - [Flights from Toronto](https://www.expedia.ca/lp/flights/178314/flights-from-toronto) - [Flights from Buffalo (BUF) to St. Catharines (YCM)](https://www.expedia.ca/lp/flights/buf/ycm/buffalo-to-st-catharines) - [Flights from Delhi (DEL) to Toronto (YYZ)](https://www.expedia.ca/lp/flights/del/yyz/delhi-to-toronto) - [Flights from Philadelphia (PHL) to St. Catharines (YCM)](https://www.expedia.ca/lp/flights/phl/ycm/philadelphia-to-st-catharines) - [Flights from Sault Ste. 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