Title: 5 Stars Hotels in Mediterranean Region, from CA $174 - Find Cheap Mediterranean Region Hotels With 5 Stars | Expedia.ca [Mediterranean Region Travel Guide](https://expedia.ca/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Vacation Rentals in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Vacation-Rentals.d844522342175883264.Travel-Guide-VacationRentals)[Flights to Mediterranean Region](https://expedia.ca/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Rentals](https://expedia.ca/Car-Rentals-In-Mediterranean-Region.d844522342175883264.Car-Rental-Guide)[Mediterranean Region Vacation Packages](https://expedia.ca/Mediterranean-Region.d844522342175883264.Destination-Travel-Guides) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Mediterranean Region, from CA $174 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mediterranean Region 5 Star Hotels Tonight [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-11&endDate=2025-12-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-12&endDate=2025-12-13&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-12&endDate=2025-12-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mediterranean Region 5-star hotels ![Daily buffet breakfast (EUR 29 per person)](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/733dd395.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/w3837h2559x3y0-1cfc3e1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/595f7b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Level Suite with 1 King Bed | Living area](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/63a2a20d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt Athens [](https://www.expedia.ca/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) Neos Kosmos 8.8/10 Excellent (996) "Great place to stay with fabulous breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) wafa CA $147 CA $174 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/a07cf64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Spanish cuisine](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/9b2b1f33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/eb19c591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/7e696b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lamaro Hotel [](https://www.expedia.ca/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) Downtown Barcelona 9.6/10 Exceptional (1815) "Excellent location, staff and property." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suhail CA $301 CA $358 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/b9edc52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/3f36a705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/42518f16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/322115e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Barcelona Tower [](https://www.expedia.ca/Barcelona-Hotels-Hyatt-Regency-Barcelona-Tower.h1337977.Hotel-Information) Bellvitge 9.0/10 Wonderful (1004) "Fantastic hotel " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) John CA $212 CA $244 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Barcelona-Hotels-Hyatt-Regency-Barcelona-Tower.h1337977.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/cad83751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/1e22c978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/2e908d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/11000/10975/b4f3b599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Palace, a Luxury Collection Hotel, Madrid [](https://www.expedia.ca/Madrid-Hotels-The-Palace.h10975.Hotel-Information) Madrid Centro 9.2/10 Wonderful (1003) "Beautiful place to stay, great location, excellent breakfast under the glass dome, wonderful staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lotfi CA $509 CA $560 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/Madrid-Hotels-The-Palace.h10975.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/0feded01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/262ddecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Select Comfort beds, minibar, in-room safe](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/3794d1c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Select Comfort beds, minibar, in-room safe](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/9224efd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barceló Torre de Madrid [](https://www.expedia.ca/Madrid-Hotels-Barcelo-Torre-De-Madrid.h15371941.Hotel-Information) Madrid Centro 9.4/10 Exceptional (2251) "Great space, great location and amazing service! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Giovanni CA $253 CA $278 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Madrid-Hotels-Barcelo-Torre-De-Madrid.h15371941.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/w3602h2700x599y0-6dfb7d2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/w3792h2700x504y0-d801270f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/w4046h2700x377y0-ae0583c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11800/11761/a77935f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Only YOU Hotel Sevilla [](https://www.expedia.ca/Seville-Hotels-Ayre-Hotel-Sevilla.h11761.Hotel-Information) San Pablo-Santa Justa 9.8/10 Exceptional (572) "Absolutely loved the hotel. It was so beautiful, lovely staff, good location and breakfast was delicious!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Ana CA $198 CA $217 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Seville-Hotels-Ayre-Hotel-Sevilla.h11761.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/7d939125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/6546e4bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/c158956b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Mediterranean cuisine](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/807a8506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Athens Airport [](https://www.expedia.ca/Athens-Hotels-Sofitel-Athens-Airport.h688125.Hotel-Information) Spata-Artemida 9.4/10 Exceptional (2619) "It was a great place to stay and eat." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) susan CA $326 CA $377 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Athens-Hotels-Sofitel-Athens-Airport.h688125.Hotel-Information) ![Suite (Nobu Suite) | View from room](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/8f615dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/d588656c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Japanese cuisine](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/31d4ab03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/f8751bcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu Hotel Barcelona [](https://www.expedia.ca/Barcelona-Hotels-Nobu-Hotel-Barcelona.h39067368.Hotel-Information) Sants-Montjuïc 9.0/10 Wonderful (1184) "Excellent staff , great location, nice and clean set up " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marianna CA $324 CA $383 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Barcelona-Hotels-Nobu-Hotel-Barcelona.h39067368.Hotel-Information) ![Premium bedding, down comforters, memory foam beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/14674ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/6387935c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Mediterranean cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/f1261972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/eae3fb84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Majestic Hotel & Spa Barcelona [](https://www.expedia.ca/Barcelona-Hotels-Majestic-Hotel-Spa-Barcelona.h5002.Hotel-Information) Eixample 9.2/10 Wonderful (1000) "Great location. Wonderful hotel. Nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Myron CA $446 CA $518 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Barcelona-Hotels-Majestic-Hotel-Spa-Barcelona.h5002.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/ac18b570.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/1f398528.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/414c1ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/8c82f92a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eurostars Grand Marina [](https://www.expedia.ca/Barcelona-Hotels-Eurostars-Grand-Marina.h871862.Hotel-Information) Downtown Barcelona 9.0/10 Wonderful (1165) "Friendly staff and conveniy" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chung Hon Johann CA $216 CA $264 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Barcelona-Hotels-Eurostars-Grand-Marina.h871862.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/6275d23f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/e8e431b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/d5bbc84b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/639d39e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Athenaeum InterContinental by IHG [](https://www.expedia.ca/Athens-Hotels-Athenaeum-InterContinental.h19591.Hotel-Information) Neos Kosmos 9.0/10 Wonderful (1000) "Very nice hotel, clean and very helpful staff. An amazing breakfast buffet." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Patricia R CA $179 CA $210 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Athens-Hotels-Athenaeum-InterContinental.h19591.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/d3bf8dce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Separate tub and shower, rainfall showerhead, hair dryer, bathrobes](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/4f0db92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast for a fee](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/af3656b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83980000/83976200/83976194/91f4ad27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### UMusic Hotel Madrid [](https://www.expedia.ca/Madrid-Hotels-UMusic-Hotel-Madrid.h83976194.Hotel-Information) Madrid Centro 9.4/10 Exceptional (774) "Great overall experience and location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre CA $275 CA $303 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Madrid-Hotels-UMusic-Hotel-Madrid.h83976194.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/1d7b7940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Club Suite, 1 King Bed, Corner | Living room](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/3ac3b366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, lunch, dinner served; Japanese cuisine](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/4255d073.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/3800/3780/04010660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Arts Barcelona [](https://www.expedia.ca/Barcelona-Hotels-Hotel-Arts-Barcelona.h3780.Hotel-Information) Sant Martí 9.0/10 Wonderful (1000) "Fabulous hotel with a very friendly staff. I would definitely recommend it and get the city view, it’s fantastic." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bruce CA $567 CA $650 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Barcelona-Hotels-Hotel-Arts-Barcelona.h3780.Hotel-Information) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/w3840h2440x0y3-e37b92aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/w3836h2556x4y3-e85eda59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/07c628df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/392f6b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt Barcelona [](https://www.expedia.ca/Barcelona-Hotels-Hotel-SOFIA-Barcelona.h17348.Hotel-Information) Les Corts 9.2/10 Wonderful (1461) "Excellent stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandro CA $234 CA $283 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Barcelona-Hotels-Hotel-SOFIA-Barcelona.h17348.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/5675b645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/4a3c096b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds (Panoramic) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/aa158b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/54400/54350/f937abbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Lisbon by IHG [](https://www.expedia.ca/Lisbon-District-Hotels-InterContinental-Lisbon.h54350.Hotel-Information) Lisbon City Center 9.2/10 Wonderful (1002) "Overall a great experience at this property! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miguel CA $250 CA $294 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Lisbon-District-Hotels-InterContinental-Lisbon.h54350.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/07fc9253.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/58f9e357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/dd91ed2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room](https://images.trvl-media.com/lodging/1000000/10000/2100/2061/7d250134.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avenida Palace [](https://www.expedia.ca/Lisbon-District-Hotels-Avenida-Palace.h2061.Hotel-Information) Lisbon City Center 9.8/10 Exceptional (1002) "Great location and wonderful breakfast" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Robert CA $408 CA $446 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Lisbon-District-Hotels-Avenida-Palace.h2061.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/3cc9c093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/938b9906.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/2e74fe8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/2000000/1200000/1199100/1199013/e516e939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Puerta América [](https://www.expedia.ca/Madrid-Hotels-Hotel-Puerta-America.h1199013.Hotel-Information) Chamartín 8.8/10 Excellent (998) "Everything was perfect and the hotel is beautiful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaias [](https://www.expedia.ca/Madrid-Hotels-Hotel-Puerta-America.h1199013.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/3df12022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite (Botet Suite) | View from room](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/11cbde6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/f2b2726d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Homey)](https://images.trvl-media.com/lodging/1000000/30000/22100/22014/w4000h2663x0y4-15bdeb6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Only YOU Hotel Valencia [](https://www.expedia.ca/Valencia-Hotels-Only-YOU-Hotel-Valencia.h22014.Hotel-Information) Valencia City Centre 9.8/10 Exceptional (959) "Lovely hotel, great location " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Paul CA $244 CA $268 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Valencia-Hotels-Only-YOU-Hotel-Valencia.h22014.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/868bd67a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/w5755h3835x5y5-21e9755b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Terrace](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/w515h796x0y4-aa8f7725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/77000000/76580000/76579100/76579070/8ca5781e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Thompson Madrid, by Hyatt [](https://www.expedia.ca/Madrid-Hotels-Thompson-Madrid.h76579070.Hotel-Information) Madrid Centro 9.6/10 Exceptional (310) "Location is great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rehan CA $410 CA $451 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Madrid-Hotels-Thompson-Madrid.h76579070.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Mediterranean cuisine](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/7b699449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/9fb8dc07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/a0ddf3f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Mediterranean cuisine](https://images.trvl-media.com/lodging/1000000/530000/527600/527569/10abab93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Electra Palace Athens [](https://www.expedia.ca/Athens-Hotels-Electra-Palace-Athens.h527569.Hotel-Information) Athens City Centre 9.6/10 Exceptional (1004) "We loved our stay here. The breakfast at the roof top restaurant was excellent, with great views. The staff was helpful and attentive. The location was convenient for sight-seeing in the city." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $256 CA $298 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Athens-Hotels-Electra-Palace-Athens.h527569.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mediterranean-Region-Hotels.s50-0-d844522342175883264.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mediterranean-Region-Hotels.s50-0-d844522342175883264.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region. ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Barcelona Airport Hotel Plaza de la Volateria, 3 El Prat de Llobregat CA $187 CA $210 total Dec 12 - Dec 13 includes taxes & fees 8.6/10 Excellent! (5,150 reviews) [](https://expedia.ca/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Bettoja Hotel Mediterraneo](https://images.trvl-media.com/lodging/1000000/10000/8800/8711/05f1eca2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Bettoja Hotel Mediterraneo Via Cavour 15 Rome RM CA $269 CA $321 total Dec 16 - Dec 17 includes taxes & fees 8.6/10 Excellent! (995 reviews) [](https://expedia.ca/Rome-Hotels-Bettoja-Hotel-Mediterraneo.h8711.Hotel-Information) ![Hotel Emperador](https://images.trvl-media.com/lodging/1000000/10000/1000/915/2f47a159_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Emperador Gran Via 53 Madrid Madrid CA $203 CA $223 total Jan 11 - Jan 12, 2026 includes taxes & fees 9.2/10 Wonderful! (1,875 reviews) [](https://expedia.ca/Madrid-Hotels-Hotel-Emperador.h915.Hotel-Information) Still don't see what you're looking for? [See all properties in Mediterranean Region.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mediterranean Region During your stay in Mediterranean Region, you can discover things to see and do in the local area. [See all hotels in Mediterranean Region](https://www.expedia.ca/Hotel-Search?startDate=2025-12-25&endDate=2025-12-26&adults=2®ionId=844522342175883264) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ## Top Mediterranean Region Hotel Reviews ![Nobu Hotel Barcelona](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/de597f46_y.jpg) ### Nobu Hotel Barcelona 10/10 Excellent "Excellent staff , great location, nice and clean set up " [](https://expedia.ca/Barcelona-Hotels-Nobu-Hotel-Barcelona.h39067368.Hotel-Information) ![Lamaro Hotel](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/a07cf64a_y.jpg) ### Lamaro Hotel 10/10 Excellent "No the laundry services were too expensive. I had to go and do it in a laundry mat." [](https://expedia.ca/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) ## Find out more about Mediterranean Region Luxury is the name of the game at the best 5 Stars hotels in Mediterranean Region. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Mediterranean Region 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them. Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Mediterranean Region hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Mediterranean Region without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Mediterranean Region.