Title: 5 Stars Hotels in Otay Mesa, San Diego from CA $260 - Find Cheap Otay Mesa Hotels With 5 Stars | Expedia.ca [Otay Mesa Travel Guide](https://expedia.ca/San-Diego-Otay-Mesa.dx6263723)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa.d6263723.Car-Rental-Guide)[Otay Mesa Vacations](https://expedia.ca/Otay-Mesa.d6263723.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Otay Mesa, San Diego from CA $260 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa 5 Star Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-24&endDate=2025-10-25&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-25&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Otay Mesa 5 Star Hotels ![3 restaurants, breakfast, lunch, dinner served; seafood](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/a2e0b6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/0c2ef40d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/ffc5e031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pendry San Diego Downtown San Diego 9.2/10 Wonderful (1002) "The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cyrus CA $315 CA $439 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/e71c0bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/10ea342c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/61ab8b94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/20000/10900/10802/d6c34b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The US Grant, a Luxury Collection Hotel, San Diego Downtown San Diego 9.0/10 Wonderful (1003) "The staff was excellent and attentive. It was centrally located to all we wished to visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $356 CA $412 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-THE-US-GRANT.h10802.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/fe94f9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium King with Orange Ave](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/c381e66d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/178c1eb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/2b448002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bower Coronado Glorietta Bay 9.2/10 Wonderful (123) "Fabulous customer service! Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) THERESA CA $260 CA $426 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Coronado-Hotels-The-Bower.h111958344.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/eaeb791a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/e17e30fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed (Horizon Suite) | Living area](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/bf3cf5a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with cable channels, fireplace, Netflix](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/w3836h2711x3y3-7839679e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beach Village at The Del, LXR Hotels & Resorts Historic Downtown Coronado 9.2/10 Wonderful (118) "Best place I’ve ever stayed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $1,033 CA $1,208 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Coronado-Hotels-Beach-Village-At-The-Del.h19656437.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Otay-Mesa-San-Diego-Hotels.s50-n6263723-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Otay-Mesa-San-Diego-Hotels.s50-n6263723-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Otay Mesa. ![Manchester Grand Hyatt San Diego](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Manchester Grand Hyatt San Diego 1 Market Pl, San Diego, CA CA $251 CA $367 total Nov 25 - Nov 26 includes taxes & fees 9/10 Wonderful! (2,857 reviews) [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![San Diego Marriott Gaslamp Quarter](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/04fbf5a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### San Diego Marriott Gaslamp Quarter 660 K St, San Diego, CA CA $225 CA $261 total Oct 28 - Oct 29 includes taxes & fees 8.6/10 Excellent! (1,580 reviews) [](https://expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Gaslamp-Quarter.h1466.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Wyndham San Diego Bayside 1355 N Harbor Drive, San Diego, CA CA $189 CA $260 total Oct 27 - Oct 28 includes taxes & fees 8.2/10 Very Good! (5,991 reviews) [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) Still don't see what you're looking for? [See all properties in Otay Mesa.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F10%2F2025&endDate=27%2F10%2F2025®ionId=6263723&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F10%2F2025&endDate=27%2F10%2F2025®ionId=6263723&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F10%2F2025&endDate=27%2F10%2F2025®ionId=6263723&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F10%2F2025&endDate=27%2F10%2F2025®ionId=6263723&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F10%2F2025&endDate=27%2F10%2F2025®ionId=6263723&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=26%2F10%2F2025&endDate=27%2F10%2F2025®ionId=6263723&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Otay Mesa Hotel Reviews ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel." [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ## Find out more about Otay Mesa ## Five Star Hotels in Otay Mesa There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Otay Mesa so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Otay Mesa and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Otay Mesa Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Otay Mesa The results are in, and Otay Mesa 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Otay Mesa! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Otay Mesa today and settle down in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Otay Mesa? > The amount you pay for a 5-star hotel in Otay Mesa depends on things like when you want to go and the length of your getaway. Our insider tip for landing an awesome deal? Use our pricing filters to compare all of the available accommodations for your selected dates. > > > > - Search for the lowest price per night from CA $260 ### What makes a hotel 5 stars in Otay Mesa? > From high-end dining venues and all-day gyms to swimming pools and premium bedding, the 5-star experience in Otay Mesa is all about luxury and relaxation. But it takes more than just top-notch perks to receive a 5-star rating. Hotels also have to deliver extraordinary guest services like beauty treatments, on-site laundry and 24-hour concierge services. ### Are there any 5-star all-inclusive resorts in Otay Mesa? > Find a luxury escape that includes your lodging, meals, drinks and entertainment in Otay Mesa with our filters. Search for resorts with a 5-star rating and click on the "All inclusive" filter. Have a look at what's included in the upfront price. This way, you'll be ready to maximize the many perks on offer from the moment you get there. ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [1 Star Hotels in San Diego](https://www.expedia.ca/1Star-San-Diego-Hotels.s10-0-d3073.Travel-Guide-Filter-Hotels) - [1 Star Hotels in San Miguel Ranch](https://www.expedia.ca/1Star-San-Miguel-Ranch-Chula-Vista-Hotels.s10-n553248635976480437-0.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Lincoln Park](https://www.expedia.ca/2Star-Lincoln-Park-San-Diego-Hotels.s20-n797413695373639680-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Chula Vista](https://www.expedia.ca/3Star-Chula-Vista-Hotels.s30-0-d7442.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Downtown San Diego](https://www.expedia.ca/3Star-Downtown-San-Diego-San-Diego-Hotels.s30-n800123-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Gaslamp Quarter](https://www.expedia.ca/3Star-Gaslamp-Quarter-San-Diego-Hotels.s30-n6130021-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Lomita](https://www.expedia.ca/3Star-Lomita-San-Diego-Hotels.s30-n797414701963595776-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Mid-City](https://www.expedia.ca/3Star-Mid-City-San-Diego-Hotels.s30-n553248635976388682-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in San Diego](https://www.expedia.ca/3Star-San-Diego-Hotels.s30-0-d3073.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Chula Vista](https://www.expedia.ca/4Star-Chula-Vista-Hotels.s40-0-d7442.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Coronado](https://www.expedia.ca/4Star-Coronado-Hotels.s40-0-d5917.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Downtown San Diego](https://www.expedia.ca/4Star-Downtown-San-Diego-San-Diego-Hotels.s40-n800123-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in La Mesa](https://www.expedia.ca/4Star-La-Mesa-Hotels.s40-0-d8484.Travel-Guide-Filter-Hotels) - [4 Star Hotels in San Diego](https://www.expedia.ca/4Star-San-Diego-Hotels.s40-0-d3073.Travel-Guide-Filter-Hotels) - [4 Star Hotels in South Bay](https://www.expedia.ca/4Star-South-Bay-Hotels.s40-0-d6056572.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Bankers Hill](https://www.expedia.ca/5Star-Bankers-Hill-San-Diego-Hotels.s50-n553248635976473812-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Chula Vista](https://www.expedia.ca/5Star-Chula-Vista-Hotels.s50-0-d7442.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Coronado](https://www.expedia.ca/5Star-Coronado-Hotels.s50-0-d5917.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Coronado Island](https://www.expedia.ca/5Star-Coronado-Island-Hotels.s50-0-d553248621532638598.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Downtown San Diego](https://www.expedia.ca/5Star-Downtown-San-Diego-San-Diego-Hotels.s50-n800123-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in El Cajon](https://www.expedia.ca/5Star-El-Cajon-Hotels.s50-0-d6632.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Gaslamp Quarter](https://www.expedia.ca/5Star-Gaslamp-Quarter-San-Diego-Hotels.s50-n6130021-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Historic Downtown Coronado](https://www.expedia.ca/5Star-Historic-Downtown-Coronado-Coronado-Hotels.s50-n855753908986241024-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Park](https://www.expedia.ca/5Star-North-Park-San-Diego-Hotels.s50-n6346499-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in San Diego Coast](https://www.expedia.ca/5Star-San-Diego-Coast-Hotels.s50-0-d553248633966884021.Travel-Guide-Filter-Hotels) - [5 Star Hotels in San Diego](https://www.expedia.ca/5Star-San-Diego-Hotels.s50-0-d3073.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Silver Strand](https://www.expedia.ca/5Star-Silver-Strand-Coronado-Hotels.s50-n855754614782734336-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in South Bay](https://www.expedia.ca/5Star-South-Bay-Hotels.s50-0-d6056572.Travel-Guide-Filter-Hotels) - [5 Star Hotels in South Park](https://www.expedia.ca/5Star-South-Park-San-Diego-Hotels.s50-n553248631819682469-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Tijuana River Valley](https://www.expedia.ca/5Star-Tijuana-River-Valley-San-Diego-Hotels.s50-n553248635976387572-0.Travel-Guide-Filter-Hotels) - [Hotels near Brown Field Municipal](https://www.expedia.ca/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Flights from Brown Field Municipal](https://www.expedia.ca/lp/airports/sdm/flights-from-brown-field-municipal-airport) - [Flights from Aspen (ASE) to San Diego (SDM)](https://www.expedia.ca/lp/flights/ase/sdm/aspen-to-san-diego) - [Flights from Barcelona (BCN) to San Diego (SDM)](https://www.expedia.ca/lp/flights/bcn/sdm/barcelona-to-san-diego) - [Flights from Bakersfield (BFL) to San Diego (SDM)](https://www.expedia.ca/lp/flights/bfl/sdm/bakersfield-to-san-diego) - [Flights from León (BJX) to San Diego (SDM)](https://www.expedia.ca/lp/flights/bjx/sdm/leon-to-san-diego) - [Flights from Bangkok (BKK) to San Diego (SDM)](https://www.expedia.ca/lp/flights/bkk/sdm/bangkok-to-san-diego) - [Flights from Bellingham (BLI) to San Diego (SDM)](https://www.expedia.ca/lp/flights/bli/sdm/bellingham-to-san-diego) - [Flights from Nashville (BNA) to San Diego (SDM)](https://www.expedia.ca/lp/flights/bna/sdm/nashville-to-san-diego) - [Flights from Burlington (BTV) to San Diego (SDM)](https://www.expedia.ca/lp/flights/btv/sdm/burlington-to-san-diego) - [Flights from Paris (CDG) to San Diego (SDM)](https://www.expedia.ca/lp/flights/cdg/sdm/paris-to-san-diego) - [Flights from Charlotte (CLT) to San Diego (SDM)](https://www.expedia.ca/lp/flights/clt/sdm/charlotte-to-san-diego) - [Flights from Compton (CPM) to San Diego (SDM)](https://www.expedia.ca/lp/flights/cpm/sdm/compton-to-san-diego) - [Flights from Cancun (CUN) to San Diego (SDM)](https://www.expedia.ca/lp/flights/cun/sdm/cancun-to-san-diego) - [Flights from Cincinnati (CVG) to San Diego (SDM)](https://www.expedia.ca/lp/flights/cvg/sdm/cincinnati-to-san-diego) - [Flights from Barstow (DAG) to San Diego (SDM)](https://www.expedia.ca/lp/flights/dag/sdm/barstow-to-san-diego) - [Flights from Denver (DEN) to San Diego (SDM)](https://www.expedia.ca/lp/flights/den/sdm/denver-to-san-diego) - [Flights from Dallas (DFW) to San Diego (SDM)](https://www.expedia.ca/lp/flights/dfw/sdm/dallas-to-san-diego) - [Flights from Detroit (DTW) to San Diego (SDM)](https://www.expedia.ca/lp/flights/dtw/sdm/detroit-to-san-diego) - [Flights from Ensenada (ESE) to San Diego (SDM)](https://www.expedia.ca/lp/flights/ese/sdm/ensenada-to-san-diego) - [Flights from Newark Liberty Intl. Airport (EWR) to San Diego (SDM)](https://www.expedia.ca/lp/flights/ewr/sdm/newark-liberty-intl-airport-to-san-diego) - [Flights from Fresno (FAT) to San Diego (SDM)](https://www.expedia.ca/lp/flights/fat/sdm/fresno-to-san-diego) - [Flights from Sierra Vista (FHU) to San Diego (SDM)](https://www.expedia.ca/lp/flights/fhu/sdm/sierra-vista-to-san-diego) - [Flights from Fort Lauderdale (FLL) to San Diego (SDM)](https://www.expedia.ca/lp/flights/fll/sdm/fort-lauderdale-to-san-diego) - [Flights from Hong Kong (HKG) to San Diego (SDM)](https://www.expedia.ca/lp/flights/hkg/sdm/hong-kong-to-san-diego) - [Flights from Hayward (HWD) to San Diego (SDM)](https://www.expedia.ca/lp/flights/hwd/sdm/hayward-to-san-diego) - [Flights from Houston (IAH) to San Diego (SDM)](https://www.expedia.ca/lp/flights/iah/sdm/houston-to-san-diego) - [Flights from Jacksonville (JAX) to San Diego (SDM)](https://www.expedia.ca/lp/flights/jax/sdm/jacksonville-to-san-diego) - [Flights from Las Vegas (LAS) to San Diego (SDM)](https://www.expedia.ca/lp/flights/las/sdm/las-vegas-to-san-diego) - [Flights from Long Beach (LGB) to San Diego (SDM)](https://www.expedia.ca/lp/flights/lgb/sdm/long-beach-to-san-diego) - [Flights from London (LHR) to San Diego (SDM)](https://www.expedia.ca/lp/flights/lhr/sdm/london-to-san-diego) - [Flights from Manchester (MAN) to San Diego (SDM)](https://www.expedia.ca/lp/flights/man/sdm/manchester-to-san-diego) - [Flights from Miami (MIA) to San Diego (SDM)](https://www.expedia.ca/lp/flights/mia/sdm/miami-to-san-diego) - [Flights from Minneapolis (MSP) to San Diego (SDM)](https://www.expedia.ca/lp/flights/msp/sdm/minneapolis-to-san-diego) - [Flights from New Orleans (MSY) to San Diego (SDM)](https://www.expedia.ca/lp/flights/msy/sdm/new-orleans-to-san-diego) - [Flights from Marysville (MYV) to San Diego (SDM)](https://www.expedia.ca/lp/flights/myv/sdm/marysville-to-san-diego) - [Flights from New York (NYC) to San Diego (SDM)](https://www.expedia.ca/lp/flights/nyc/sdm/new-york-to-san-diego) - [Flights from Oklahoma City (OKC) to San Diego (SDM)](https://www.expedia.ca/lp/flights/okc/sdm/oklahoma-city-to-san-diego) - [Flights from Oslo (OSL) to San Diego (SDM)](https://www.expedia.ca/lp/flights/osl/sdm/oslo-to-san-diego) - [Flights from Portland (PDX) to San Diego (SDM)](https://www.expedia.ca/lp/flights/pdx/sdm/portland-to-san-diego) - [Flights from Perth (PER) to San Diego (SDM)](https://www.expedia.ca/lp/flights/per/sdm/perth-to-san-diego) - [Flights from Phoenix (PHX) to San Diego (SDM)](https://www.expedia.ca/lp/flights/phx/sdm/phoenix-to-san-diego) - [Flights from Pasco (PSC) to San Diego (SDM)](https://www.expedia.ca/lp/flights/psc/sdm/pasco-to-san-diego) - [Flights from Provo (PVU) to San Diego (SDM)](https://www.expedia.ca/lp/flights/pvu/sdm/provo-to-san-diego) - [Flights from Richmond (RIC) to San Diego (SDM)](https://www.expedia.ca/lp/flights/ric/sdm/richmond-to-san-diego) - [Flights from Rochester (ROC) to San Diego (SDM)](https://www.expedia.ca/lp/flights/roc/sdm/rochester-to-san-diego) - [Flights from San Antonio (SAT) to San Diego (SDM)](https://www.expedia.ca/lp/flights/sat/sdm/san-antonio-to-san-diego) - [Flights from Seattle (SEA) to San Diego (SDM)](https://www.expedia.ca/lp/flights/sea/sdm/seattle-to-san-diego) - [Flights from San Francisco (SFO) to San Diego (SDM)](https://www.expedia.ca/lp/flights/sfo/sdm/san-francisco-to-san-diego) - [Flights from Shreveport (SHV) to San Diego (SDM)](https://www.expedia.ca/lp/flights/shv/sdm/shreveport-to-san-diego) - [Flights from San José del Cabo (SJD) to San Diego (SDM)](https://www.expedia.ca/lp/flights/sjd/sdm/san-jose-del-cabo-to-san-diego) - [Flights from Sacramento (SMF) to San Diego (SDM)](https://www.expedia.ca/lp/flights/smf/sdm/sacramento-to-san-diego) - [Flights from Orange County (SNA) to San Diego (SDM)](https://www.expedia.ca/lp/flights/sna/sdm/orange-county-to-san-diego) - [Flights from Sydney (SYD) to San Diego (SDM)](https://www.expedia.ca/lp/flights/syd/sdm/sydney-to-san-diego) - [Flights from Syracuse (SYR) to San Diego (SDM)](https://www.expedia.ca/lp/flights/syr/sdm/syracuse-to-san-diego) - [Flights from Tijuana (TIJ) to San Diego (SDM)](https://www.expedia.ca/lp/flights/tij/sdm/tijuana-to-san-diego) - [Flights from Tucson (TUS) to San Diego (SDM)](https://www.expedia.ca/lp/flights/tus/sdm/tucson-to-san-diego) - [Flights from Lake Tahoe (TVL) to San Diego (SDM)](https://www.expedia.ca/lp/flights/tvl/sdm/lake-tahoe-to-san-diego) - [Flights from Edmonton (YEG) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yeg/sdm/edmonton-to-san-diego) - [Flights from Halifax (YHZ) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yhz/sdm/halifax-to-san-diego) - [Flights from Sudbury (YSB) to San Diego (SDM)](https://www.expedia.ca/lp/flights/ysb/sdm/sudbury-to-san-diego) - [Flights from Toronto (YTO) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yto/sdm/toronto-to-san-diego) - [Flights from Montreal (YUL) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yul/sdm/montreal-to-san-diego) - [Flights from Vancouver (YVR) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yvr/sdm/vancouver-to-san-diego) - [Flights from Winnipeg (YWG) to San Diego (SDM)](https://www.expedia.ca/lp/flights/ywg/sdm/winnipeg-to-san-diego) - [Flights from Saskatoon (YXE) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yxe/sdm/saskatoon-to-san-diego) - [Flights from Calgary (YYC) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yyc/sdm/calgary-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (SDM)](https://www.expedia.ca/lp/flights/yyz/sdm/toronto-to-san-diego) - [Flights from Zürich (ZRH) to San Diego (SDM)](https://www.expedia.ca/lp/flights/zrh/sdm/zurich-to-san-diego) - [Rental cars Brown Field Municipal airport](https://www.expedia.ca/Car-Rentals-In-Brown-Field-Municipal.d6031787.Car-Rental-Guide) - [Book Hotels in Otay Mesa on Expedia.com](https://www.expedia.com/5Star-Otay-Mesa-San-Diego-Hotels.s50-n6263723-0.Travel-Guide-Filter-Hotels)