Title: 5 Stars Hotels in Lower Keys, Florida  - Find Cheap Lower Keys Hotels With 5 Stars | Expedia.ca

  

[Lower Keys Travel Guide](https://expedia.ca/Lower-Keys.dx553248621593965863)[Hotels in Lower Keys](https://expedia.ca/Lower-Keys-Hotels.d553248621593965863.Travel-Guide-Hotels)[Vacation Rentals in Lower Keys](https://expedia.ca/Lower-Keys-Vacation-Rentals.d553248621593965863.Travel-Guide-VacationRentals)[Flights to Lower Keys](https://expedia.ca/Cheap-Flights-To-Lower-Keys.d553248621593965863.Travel-Guide-Flights)[Things to do in Lower Keys](https://expedia.ca/Things-To-Do-In-Lower-Keys.d553248621593965863.Travel-Guide-Activities)[Lower Keys Car Rentals](https://expedia.ca/Car-Rentals-In-Lower-Keys.d553248621593965863.Car-Rental-Guide)[Lower Keys Vacation Packages](https://expedia.ca/Lower-Keys.d553248621593965863.Destination-Travel-Guides)

![Big Pine Key featuring a bay or harbour, general coastal views and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63852-Big-Pine-Key.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# 5 Stars Hotels in Lower Keys, Florida

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## Check availability on Lower Keys 5 Star Hotels

Tonight

[Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=553248621593965863&startDate=2025-10-23&endDate=2025-10-24&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=553248621593965863&startDate=2025-10-24&endDate=2025-10-25&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248621593965863&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248621593965863&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Lower Keys 5 Star Hotels

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Keys.

![3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly](https://images.trvl-media.com/lodging/72000000/71750000/71747700/71747663/9b8c25e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### 3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

Big Pine Key

[Get rates](https://expedia.ca/Hotel-Search?startDate=06%2F11%2F2025&endDate=07%2F11%2F2025&selected=71747663&PinnedHotelID=71747663&HadPinnedHotel=true&regionId=553248621593965863)

[](https://expedia.ca/Big-Pine-Key-Hotels-3-Bedroom-House-In-Lower-Keys-With-Hot-Tub.h71747663.Hotel-Information)

Still don't see what you're looking for?

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You can also use these popular filters to refine your search.

[Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025&regionId=553248621593965863&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025&regionId=553248621593965863&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025&regionId=553248621593965863&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025&regionId=553248621593965863&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F10%2F2025&endDate=25%2F10%2F2025&regionId=553248621593965863&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Lower Keys

Explore the relaxing area of Lower Keys—parks, boating, and sights from Sugarloaf Beach to Calusa Beach.

[See all hotels in Lower Keys](https://www.expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07&adults=2&regionId=553248621593965863)

![Sugarloaf Shores showing a bay or harbor and a sunset](https://images.trvl-media.com/place/6270983/d55f2489-0176-4d5a-82e3-d6afdd04d6e6.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Lower Keys Hotel Reviews

## Find out more about Lower Keys

Luxury is the name of the game at the best 5 Stars hotels in Lower Keys. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Lower Keys 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Lower Keys hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Lower Keys without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Lower Keys.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Lower Keys?

> How much you pay for a 5-star hotel in Lower Keys can vary depending on when you want to travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to find the best deal on a high-end stay.
> 
>   
> 
> -   Search for the lowest price per night

### What makes a hotel 5 stars in Lower Keys?

> Exemplary guest service characterizes every 5-star hotel in Lower Keys. From the minute you step through the door, staff cater to your every need, whether arranging valet parking or providing in-room massage treatments. On top of that, hotels have to feature superior amenities to be considered for a 5-star rating. These can include luxury bathrooms, on-site spa facilities, pools, fine dining restaurants and knowledgeable concierge.

### Are there any 5-star all-inclusive resorts in Lower Keys?

> Find a luxury retreat that includes your lodging, meals, bar and entertainment in Lower Keys with the help of Expedia's filter tool. Search for hotels with a 5-star rating and select the "All inclusive" filter. Make sure you check what's included in the upfront price. This way, you'll be ready to maximize the many perks on offer when you get there.

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