Title: 4 Stars Hotels in Southern Indiana, United States of America from CA $131 - Find Cheap Southern Indiana Hotels With 4 Stars | Expedia.ca

[Southern Indiana Travel Guide](https://expedia.ca/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.ca/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Southern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Southern Indiana 4 Star Hotels

Tonight

[Mar 21 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-03-21&endDate=2026-03-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 22 - Mar 23](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-03-22&endDate=2026-03-23&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southern Indiana 4-star hotels

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/aa5bcd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/63654a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/0261f02d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9d86b349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(4,079 reviews)

"Room was great, hotel was clean"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jordan

CA $171

CA $202 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Corner | Living area](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/07f1fa14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/408d438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1,172 reviews)

"Great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $157

CA $185 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/764d3439.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,179 reviews)

"Awesome staff, beautiful hotel, great food and bar"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jason

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/1b9613a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w2691h3837x0y3-df7daefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w3836h2558x4y3-11fbb096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/9764f52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Genevieve part of JdV by Hyatt

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1,061 reviews)

"Love this hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gina

CA $185

CA $218 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/1c073add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/14a187ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/19be2c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Louisville Marriott Downtown

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1,000 reviews)

"We had a great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacob

CA $230

CA $271 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,003 reviews)

"Lovely hotel. Would stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kristin Woxland

CA $246

CA $296 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/e017e8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/ecfda21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/06086a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (VIP)](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/b7d53e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Louisville

[](https://www.expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

Downtown Louisville

8.8/10

Excellent

(1,000 reviews)

"Nice property, friendly staff, great downtown location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew

CA $188

CA $221 total

includes taxes & fees

Apr 4 - Apr 5

[](https://www.expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/ac66f01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/8fba23fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/939655b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/16484a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Distil, Autograph Collection

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(456 reviews)

"Great hotel & location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ana

CA $240

CA $283 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e116c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f5558cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e68de90e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/765b8556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Grady

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,001 reviews)

"The decor was so charming and the Wild Swann was fabulous! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kelly

CA $221

CA $260 total

includes taxes & fees

Apr 1 - Apr 2

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/cea1a8d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/1b6f8c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/60d711ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/954cf753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Evansville

[](https://www.expedia.ca/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information)

Downtown Evansville

8.6/10

Excellent

(1,003 reviews)

"The entire stay was perfect from check in to check out"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephen

CA $168

CA $193 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/5c616865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/f1158083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/cb95631e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, American cuisine](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/12fca7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Bourré Bonne Louisville, Curio Collection by Hilton

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(85 reviews)

"Very friendly and helpful staff. Hotel is clean and wonderful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emily

CA $197

CA $232 total

includes taxes & fees

Apr 3 - Apr 4

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/d22f4bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/w3839h2557x0y0-ff0d1f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/12e6fe89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hilton, Deluxe Suite, 1 Queen Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/83bc3758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seelbach Hilton Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

Downtown Louisville

8.6/10

Excellent

(1,001 reviews)

"All over very well maintained rooms very clean and comfortable, bathrooms very small room by elevator very loud, bartender very good! Over all great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amber

CA $201

CA $236 total

includes taxes & fees

Apr 3 - Apr 4

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/3f80acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/89d26e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/af58ac58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stellar Suites

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(128 reviews)

"Easy check in and check out process and very convenient location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

CA $159

CA $257 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/ee4c1d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/5cef01cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/3ff12f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor wedding area](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/19f1cd24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Pepin Mansion Historic B&B

[](https://www.expedia.ca/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

New Albany

9.8/10

Exceptional

(673 reviews)

"It was wonderful. I would stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chassity

CA $115

CA $131 total

includes taxes & fees

Mar 23 - Mar 24

[](https://www.expedia.ca/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/2e0c62b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/af73a8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Non Smoking](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/48d338aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Non Smoking | In-room dining](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/57a6d9c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### CozySuites at Nulu

[](https://www.expedia.ca/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

Downtown Louisville

8.0/10

Very good

(27 reviews)

"Wonderful stay - great spot and lots of great dining options and bars nearby "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roy

CA $95

CA $269 total

includes taxes & fees

Mar 23 - Mar 24

[](https://www.expedia.ca/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/116000000/115470000/115461100/115461013/bf5e8466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/116000000/115470000/115461100/115461013/34303805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/116000000/115470000/115461100/115461013/w1080h710x0y0-5253aa5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/116000000/115470000/115461100/115461013/0378b689.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bourbon Barrel Inn Bed & Breakfast

[](https://www.expedia.ca/Louisville-Hotels-Bourbon-Barrel-Inn-Bed-Breakfast.h115461013.Hotel-Information)

Old Louisville

10/10

Exceptional

(4 reviews)

"Inn Keepers were wonderful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jonathan

[](https://www.expedia.ca/Louisville-Hotels-Bourbon-Barrel-Inn-Bed-Breakfast.h115461013.Hotel-Information)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/a0c5fbcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Reserve on Main

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

Downtown Louisville

10/10

Exceptional

(1 review)

"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

georgios

CA $226

CA $331 total

includes taxes & fees

Mar 23 - Mar 24

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/bb9c61a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e576ef26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/6ec16319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e4c43211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### stayAPT Suites Louisville North-Clarksville

[](https://www.expedia.ca/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

Clarksville

9.8/10

Exceptional

(46 reviews)

"room very good i love hotel ❤️"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kartar

[](https://www.expedia.ca/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

![Family House, Multiple Beds | Private kitchen](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/3b698b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/8410ecaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Multiple Beds | View from room](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/fa524ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Multiple Beds | Living area](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/b618c806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

[](https://www.expedia.ca/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

Sellersburg

9.4/10

Exceptional

(10 reviews)

"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

[](https://www.expedia.ca/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/bdbbecb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/66f2648f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/98663241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Evansville Airport

[](https://www.expedia.ca/Evansville-Hotels-Holiday-Inn-Evansville-Airport.h19261.Hotel-Information)

Evansville

8.0/10

Very good

(604 reviews)

"Nice hotel but it doesn’t have a fridge in the room or microwave."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.ca/Evansville-Hotels-Holiday-Inn-Evansville-Airport.h19261.Hotel-Information)

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## Learn more about Southern Indiana

Live music, casinos, and sights from Patoka Lake Swimming Beach to Patoka Lake—discover it all in Southern Indiana.

[See all hotels in Southern Indiana](https://www.expedia.ca/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06&adults=2&regionId=6059635)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Southern Indiana Hotel Reviews

![DoubleTree by Hilton Evansville](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/cea1a8d7_y.jpg)

### DoubleTree by Hilton Evansville

2/10 Terrible

"Be aware! Cleaning poor, bugs!! Staff seemed nice but wouldn't refund fully because I didn't give required notice for check out. Had to toss stuff in addition to lost money from bugs!!!!! Hotels.com offered me $50 to replace my thrown out items. Obviously no clue things aren't priced like 1950 anymore! I didn’t spend 1 night, only checked in prior to event. Should have had full refund! I'm never using this site or hotel brand again. "

[](https://expedia.ca/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information)

## Find out more about Southern Indiana

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Southern Indiana are calling your name. Known for providing first-rate service in amazing locations, each of the Southern Indiana 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Southern Indiana. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Southern Indiana, United States of America, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Southern Indiana hotels with 4 Stars provide everything you need to unwind in style.

## Frequently asked questions

### What are the best 4-star hotels in Southern Indiana?

### How much does it cost to stay in a 4-star hotel in Southern Indiana?

> - Search for the lowest price from CA $131

### What's the difference between 5-star and 4-star hotels in Southern Indiana?

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