Title: 4 Stars Hotels in Southern Indiana, United States of America from CA $136 - Find Cheap Southern Indiana Hotels With 4 Stars | Expedia.ca

[Southern Indiana Travel Guide](https://expedia.ca/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.ca/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Southern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# 4 Stars Hotels in Southern Indiana, United States of America from CA $136

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## Check availability on Southern Indiana 4 Star Hotels

Tonight

[Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-12-17&endDate=2025-12-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-12-18&endDate=2025-12-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southern Indiana 4-star hotels

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/e725185b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Bedrooms, Non Smoking (East Twr, Waterview, 2 Queens, 1 King)](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/38ee770d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(3866)

"Beautiful room and great hospitality. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chase

CA $183

CA $216 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/78105fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free toiletries, hair dryer, bathrobes, towels](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/326a55bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 6:30 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omni Louisville Hotel

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1734)

"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bonnie

CA $230

CA $271 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/edc62f96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/408d438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1117)

"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shunskis

CA $157

CA $184 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1155)

"Staff and breakfast was exceptional! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alicia

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/1b9613a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, rooftop bar](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/8178d3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/9764f52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w3836h2558x4y3-11fbb096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Genevieve part of JdV by Hyatt

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1016)

"Great location and accommodations."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steve

CA $175

CA $206 total

includes taxes & fees

Dec 24 - Dec 25

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1000)

"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

CA $191

CA $232 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/e017e8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/ecfda21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/06086a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/1a50697e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Louisville

[](https://www.expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

Downtown Louisville

8.8/10

Excellent

(1002)

"Enjoyed our stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jedediah

CA $138

CA $162 total

includes taxes & fees

Dec 27 - Dec 28

[](https://www.expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e116c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f5558cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/765b8556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Single Room, 1 King Bed, City View](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f924fe21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Grady

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1002)

"Such an amazing hotel...restaurant is delicious! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig

CA $199

CA $235 total

includes taxes & fees

Dec 24 - Dec 25

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/6f6867fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/19be2c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/14a187ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Louisville Marriott Downtown

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1000)

"Very nice hotel. Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brad

CA $233

CA $274 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/ac66f01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/8fba23fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/cf849375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/16484a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Distil, Autograph Collection

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(428)

"Great location. Great restraunt, great staff. Pleasurable experience!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Harrison

CA $241

CA $283 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/cea1a8d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/1eebe4a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/1b6f8c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/954cf753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Evansville

[](https://www.expedia.ca/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information)

Downtown Evansville

8.6/10

Excellent

(1000)

"The staff were extremely friendly "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jill

CA $134

CA $154 total

includes taxes & fees

Jan 18 - Jan 19, 2026

[](https://www.expedia.ca/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/5c616865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/cb95631e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, American cuisine](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/12fca7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Corner](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/c93e1deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Bourré Bonne Louisville, Curio Collection by Hilton

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(54)

"Lovely hotel in downtown Louisville. Well appointed room, comfy bed and outstanding dining. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michelle

CA $232

CA $272 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/d22f4bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hilton, Deluxe Suite, 1 Queen Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/83bc3758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/w3839h2557x0y0-ff0d1f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seelbach Hilton Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

Downtown Louisville

8.6/10

Excellent

(1004)

"Excellent location and a great lobby bar with a top notch bourbon selection. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

vincent

CA $176

CA $207 total

includes taxes & fees

Dec 25 - Dec 26

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/3f80acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/d0d55041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/89d26e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stellar Suites

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(117)

"Clean and great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Greg

CA $136

CA $230 total

includes taxes & fees

Jan 9 - Jan 10, 2026

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/ee4c1d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor wedding area](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/19f1cd24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/3ff12f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/5cef01cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Pepin Mansion Historic B&B

[](https://www.expedia.ca/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

New Albany

9.8/10

Exceptional

(648)

"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kathy

CA $120

CA $136 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/2e0c62b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Non Smoking | In-room dining](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/57a6d9c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Non Smoking](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/48d338aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/w2493h1667x0y0-491d9ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### CozySuites at Nulu

[](https://www.expedia.ca/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

Downtown Louisville

8.2/10

Very good

(26)

"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $95

CA $270 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/bb9c61a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/6ec16319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e4c43211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e576ef26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### stayAPT Suites Louisville North-Clarksville

[](https://www.expedia.ca/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

Clarksville

9.8/10

Exceptional

(43)

"Excellent stay. One of my favorite hotels in the area. They never disappoint "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Julia

CA $205

CA $232 total

includes taxes & fees

Dec 20 - Dec 21

[](https://www.expedia.ca/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/a0c5fbcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/eec2d0c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Reserve on Main

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

Downtown Louisville

10/10

Exceptional

(1)

"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

georgios

CA $227

CA $332 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

![Family House, Multiple Beds | Private kitchen](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/3b698b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/8410ecaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/aebabcae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Multiple Beds | Living area](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/b618c806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

[](https://www.expedia.ca/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

Sellersburg

9.4/10

Exceptional

(10)

"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

[](https://www.expedia.ca/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/bdbbecb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/98663241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/19300/19261/66f2648f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Evansville Airport

[](https://www.expedia.ca/Evansville-Hotels-Holiday-Inn-Evansville-Airport.h19261.Hotel-Information)

Evansville

8.0/10

Very good

(604)

"Nice hotel but it doesn’t have a fridge in the room or microwave."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.ca/Evansville-Hotels-Holiday-Inn-Evansville-Airport.h19261.Hotel-Information)

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## Learn more about Southern Indiana

Live music, casinos, and sights from Patoka Lake Swimming Beach to Patoka Lake—discover it all in Southern Indiana.

[See all hotels in Southern Indiana](https://www.expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02&adults=2&regionId=6059635)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Southern Indiana Hotel Reviews

![DoubleTree by Hilton Evansville](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/b1976648_y.jpg)

### DoubleTree by Hilton Evansville

10/10 Excellent

"I've stayed at this hotel many times for the Thanksgiving weekend. This is the first year that I have had to pay for parking in the deck behind the hotel. I'm not clear if it is the hotel parking lot, but I was charged $17.50 to stay overnight. I wish this had been made clear when I booked as the room might not have seemed such a bargain. When I inquired about it I was told that they are now charging to park and that there were two free parking lots/decks within walking distance. Please add that info to your website for the mobility impaired!"

[](https://expedia.ca/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information)

## Find out more about Southern Indiana

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Southern Indiana are calling your name. Known for providing first-rate service in amazing locations, each of the Southern Indiana 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Southern Indiana. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Southern Indiana, United States of America, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Southern Indiana hotels with 4 Stars provide everything you need to unwind in style.

## Frequently asked questions

### What are the best 4-star hotels in Southern Indiana?

### How much does it cost to stay in a 4-star hotel in Southern Indiana?

> - Search for the lowest price from CA $136

### What's the difference between 5-star and 4-star hotels in Southern Indiana?

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